KEGG   ENZYME: 3.2.1.130Help
Entry
EC 3.2.1.130                Enzyme                                 

Name
glycoprotein endo-alpha-1,2-mannosidase;
glucosylmannosidase;
endo-alpha-D-mannosidase;
endo-alpha-mannosidase;
endomannosidase;
glucosyl mannosidase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
glycoprotein glucosylmannohydrolase
Reaction(IUBMB)
Hydrolysis of the terminal alpha-D-glucosyl-(1,3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide component of the glycoprotein produced in the Golgi membrane
Comment
Involved in the synthesis of glycoproteins.
History
EC 3.2.1.130 created 1990
Orthology
K15538  
glycoprotein endo-alpha-1,2-mannosidase
Genes
HSA: 
79694(MANEA)
PTR: 
472074(MANEA)
PPS: 
100996027(MANEA)
GGO: 
101153501(MANEA)
PON: 
100174316(MANEA)
MCC: 
MCF: 
102131103(MANEA)
MMU: 
242362(Manea)
RNO: 
140808(Manea)
CGE: 
100682532(Manea)
HGL: 
101724745(Manea)
TUP: 
102470618(MANEA)
CFA: 
481925(MANEA)
AML: 
FCA: 
101101567(MANEA)
PTG: 
102953225(MANEA)
BTA: 
512853(MANEA)
BOM: 
102266362(MANEA)
PHD: 
102325762(MANEA)
CHX: 
102190879(MANEA)
OAS: 
101106778(MANEA)
SSC: 
100154996(MANEA)
CFR: 
102505037(MANEA)
BACU: 
LVE: 
103075786(MANEA)
ECB: 
100065922(MANEA)
MYB: 
MYD: 
102761757(MANEA)
PALE: 
102881260(MANEA)
MDO: 
100026589(MANEA)
SHR: 
100925449(MANEA)
OAA: 
100073892(MANEA)
GGA: 
421807(MANEA)
MGP: 
100538669(MANEA)
TGU: 
100227255(MANEA)
FAB: 
101815462(MANEA)
PHI: 
102108129(MANEA)
APLA: 
101799379(MANEA)
FPG: 
101917050(MANEA)
FCH: 
102050839(MANEA)
CLV: 
102091008(MANEA)
ASN: 
102374994(MANEA)
AMJ: 
102571324(MANEA)
PSS: 
102444522(MANEA)
CMY: 
102943683(MANEA)
ACS: 
100561214(manea)
PBI: 
103065662(MANEA)
XLA: 
446517(maneal)
XTR: 
DRE: 
447827(manea) 566679(maneal)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102347276(MANEA)
CMK: 
103178280(manea) 103179587(maneal)
BFO: 
SPU: 
NVI: 
PHU: 
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
CRE: 
VCN: 
CVR: 
ACAN: 
EHX: 
GTT: 
NGR: 
 » show all
Taxonomy
Reference
1  [PMID:3818665]
  Authors
Lubas WA, Spiro RG.
  Title
Golgi endo-alpha-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme.
  Journal
J. Biol. Chem. 262 (1987) 3775-81.
Reference
2  [PMID:2407194]
  Authors
Tulsiani DR, Coleman VD, Touster O.
  Title
Asparagine-linked glycoprotein biosynthesis in rat brain: identification of glucosidase I, glucosidase II, and and endomannosidase (glucosyl mannosidase).
  Journal
Arch. Biochem. Biophys. 277 (1990) 114-21.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
108022-16-8

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