| Entry |
|
|---|
| Name |
chitosanase |
|---|
| Class |
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl
compounds
 |
|---|
| Sysname |
chitosan N-acetylglucosaminohydrolase |
|---|
| Reaction(IUBMB) |
Endohydrolysis of beta-(1->4)-linkages between D-glucosamine
residues in a partly acetylated chitosan |
|---|
| Reaction(KEGG) |
(other) R02833 R06175(G)
 |
|---|
| Comment |
A whole spectrum of chitosanases are now known (for more details,
see http://pages.usherbrooke.ca/rbrzezinski/). They can hydrolyse
various types of links in chitosan. The only constant property is
the endohydrolysis of GlcN-GlcN links, which is common to all known
chitosanases. One known chitosanase is limited to this link
recognition [4], while the majority can also recognize GlcN-GlcNAc
links or GlcNAc-GlcN links but not both. They also do not recognize
GlcNAc-GlcNAc links in partly acetylated chitosan. |
|---|
| Pathway |
PATH: ec00520 Amino sugar and nucleotide sugar metabolism |
|---|
| Orthology |
KO: K01233 chitosanase |
|---|
| Genes |
AFM: AFUA_3G14980 AFUA_4G01290 AFUA_6G00500 AFUA_8G00930
ANG: An03g05260
CVI: CV_3931
BSU: BSU26890(csn)
 |
|---|
| Structures |
PDB: 1QGI 1V5C 1V5D 2D05 |
|---|
Reference
Authors
Title
Journal
|
1
Fenton, D.M. and Eveleigh, D.E.
Purification and mode of action of a chitosanase from Penicillium
islandicum.
J. Gen. Microbiol. 126 (1981) 151-165. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:10521473]
Saito J, Kita A, Higuchi Y, Nagata Y, Ando A, Miki K.
Crystal structure of chitosanase from Bacillus circulans MH-K1 at
1.6-A resolution and its substrate recognition mechanism.
J. Biol. Chem. 274 (1999) 30818-25.
Bacillus circulans |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:1368330]
Izume M, Nagae S, Kawagishi H, Mitsutomi M, Ohtakara A.
Action pattern of Bacillus sp. no. 7-M chitosanase on partially
N-acetylated chitosan.
Biosci. Biotechnol. Biochem. 56 (1992) 448-53.
Bacillus sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:8564542]
Marcotte EM, Monzingo AF, Ernst SR, Brzezinski R, Robertus JD.
X-ray structure of an anti-fungal chitosanase from streptomyces
N174.
Nat. Struct. Biol. 3 (1996) 155-62.
Streptomyces sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.2.1.132
IUBMB Enzyme Nomenclature: 3.2.1.132
ExPASy - ENZYME nomenclature database: 3.2.1.132
BRENDA, the Enzyme Database: 3.2.1.132
CAS: 51570-20-8 |
|---|
