KEGG   ENZYME: 3.2.1.132Help
Entry
EC 3.2.1.132                Enzyme                                 

Name
chitosanase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
chitosan N-acetylglucosaminohydrolase
Reaction(IUBMB)
Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan
Reaction(KEGG)
(other) R02833 R06175(G)
Show
Comment
A whole spectrum of chitosanases are now known (for more details, see {http://rbrzezinski.recherche.usherbrooke.ca/::http://rbrzezinski.recherche.usherbrooke.ca/}). They can hydrolyse various types of links in chitosan. The only constant property is the endohydrolysis of GlcN-GlcN links, which is common to all known chitosanases. One known chitosanase is limited to this link recognition [4], while the majority can also recognize GlcN-GlcNAc links or GlcNAc-GlcN links but not both. They also do not recognize GlcNAc-GlcNAc links in partly acetylated chitosan.
History
EC 3.2.1.132 created 1990, modified 2004
Pathway
Amino sugar and nucleotide sugar metabolism
Biosynthesis of secondary metabolites
Orthology
K01233  
chitosanase
Genes
AFM: 
ACT: 
NFI: 
PCS: 
CJA: 
CVI: 
BRH: 
BGD: 
JAG: 
GJA_1109(csn) GJA_1110(csn) GJA_1111(csn) GJA_1112(csn) GJA_1802(csn) GJA_1803(csn)
NII: 
DAR: 
TMZ: 
MSD: 
CCX: 
PLA: 
HNI: 
BSU: 
BSR: 
BSL: 
BSH: 
BSY: 
BST: 
BSO: 
BSN: 
BSQ: 
BSUB: 
BSX: 
BSP: 
BAO: 
BAY: 
BAQ: 
BYA: 
BAMP: 
BAML: 
BAMA: 
BAMN: 
BAMB: 
BAMT: 
BAZ: 
BQL: 
BXH: 
BQY: 
BAMI: 
BAMC: 
BAMF: 
BAE: 
BJS: 
PPM: 
PPO: 
PPOL: 
PPQ: 
PCE: 
CBE: 
CSH: 
SCO: 
SCO0677(csn) SCO2024(SC3A3.02)
SMA: 
SAV_6191(csn2)
SSX: 
SVL: 
SCT: 
SCY: 
SFA: 
SBH: 
SHY: 
SHO: 
SDV: 
SALB: 
STRP: 
SFI: 
SCI: 
SRC: 
SALU: 
KSK: 
KSE_15150(csn1) KSE_40860(csn2) KSE_40930(csn3)
RSA: 
SRO: 
AMD: 
AMN: 
AMM: 
AMZ: 
AOI: 
AMI: 
KAL: 
AMS: 
ASE: 
ACPL_2150(csn) ACPL_7579(csn2)
ACTN: 
AFS: 
 » show all
Taxonomy
Reference
1
  Authors
Fenton, D.M. and Eveleigh, D.E.
  Title
Purification and mode of action of a chitosanase from Penicillium islandicum.
  Journal
J. Gen. Microbiol. 126 (1981) 151-165.
Reference
2  [PMID:10521473]
  Authors
Saito J, Kita A, Higuchi Y, Nagata Y, Ando A, Miki K.
  Title
Crystal structure of chitosanase from Bacillus circulans MH-K1 at 1.6-A resolution and its substrate recognition mechanism.
  Journal
J. Biol. Chem. 274 (1999) 30818-25.
  Organism
Bacillus circulans
  Sequence
[up:P33673]
Reference
3  [PMID:1368330]
  Authors
Izume M, Nagae S, Kawagishi H, Mitsutomi M, Ohtakara A.
  Title
Action pattern of Bacillus sp. no. 7-M chitosanase on partially N-acetylated chitosan.
  Journal
Biosci. Biotechnol. Biochem. 56 (1992) 448-53.
  Organism
Bacillus sp.
Reference
4  [PMID:8564542]
  Authors
Marcotte EM, Monzingo AF, Ernst SR, Brzezinski R, Robertus JD.
  Title
X-ray structure of an anti-fungal chitosanase from streptomyces N174.
  Journal
Nat. Struct. Biol. 3 (1996) 155-62.
  Organism
Streptomyces sp.
  Sequence
[up:P33665]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51570-20-8

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