KEGG   ENZYME: 3.2.1.170Help
Entry
EC 3.2.1.170                Enzyme                                 

Name
mannosylglycerate hydrolase;
2-O-(6-phospho-mannosyl)-D-glycerate hydrolase;
alpha-mannosidase (ambiguous);
mngB (gene name)
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate acylhydrolase
Reaction(IUBMB)
2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate + H2O = D-mannose 6-phosphate + D-glycerate [RN:R09645]
Reaction(KEGG)
Substrate
2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate [CPD:C16699];
H2O [CPD:C00001]
Product
D-mannose 6-phosphate [CPD:C00275];
D-glycerate [CPD:C00258]
Comment
The enzyme participates in the mannosylglycerate degradation pathway of some bacteria. Mannosylglycerate is phosphorylated during transport into the cell, and the phosphorylated form is hydrolysed by this enzyme.
History
EC 3.2.1.170 created 2011
Orthology
K15524  
mannosylglycerate hydrolase
Genes
ECO: 
b0732(mngB)
ECJ: 
Y75_p0711(mngB)
ECD: 
EBW: 
BWG_0590(mngB)
ECOK: 
EOJ: 
EOI: 
EOH: 
ECW: 
ECY: 
ECR: 
ECK: 
ELH: 
ESE: 
ESO: 
ESM: 
ESL: 
ECL: 
EBR: 
ECB_00691(ybgG)
EBD: 
EKO: 
EKF: 
EDH: 
EDJ: 
ENA: 
EUN: 
ELW: 
ECW_m0786(mngB)
ELL: 
WFL_03835(mngB)
ELP: 
EBL: 
ECD_00691(ybgG)
EBE: 
B21_00680(mngB)
ECOA: 
ECOL: 
ECOJ: 
EFE: 
EFER_2372(mngB)
SBG: 
SBG_0635(mngB)
SBZ: 
SFL: 
SF0565(ybgG)
SFX: 
S0578(ybgG)
SFV: 
SFV_0604(ybgG)
SFE: 
SFxv_0623(mngB)
SSJ: 
ENC: 
ENO: 
ECLO: 
EEC: 
ESC: 
EAS: 
EAU: 
ESA: 
CSK: 
ES15_2698(mngB)
CSZ: 
CTU: 
CTU_13380(mngB)
CKO: 
PAM: 
PANA_2342(ybgG)
PLF: 
PAJ: 
PAJ_1642(ybgG)
PAQ: 
RAQ: 
EBF: 
VSP: 
VEJ: 
VFU: 
AVR: 
GAP: 
BPU: 
BPUM: 
GYC: 
GYA: 
LMO: 
LMF: 
LMH: 
LMC: 
LMN: 
LMY: 
LMT: 
LMG: 
LMS: 
LMJ: 
LMQ: 
LML: 
LMP: 
LMW: 
LMX: 
LMZ: 
LMON: 
LMOC: 
LMOS: 
LMOO: 
LMOY: 
LMOT: 
LMOA: 
LMOL: 
LMOG: 
LMOE: 
LMOB: 
LMOJ: 
LMOZ: 
LMOD: 
LMOW: 
LMOX: 
LMOQ: 
LMR: 
LIN: 
LWE: 
PPOL: 
PPQ: 
PTA: 
LLK: 
LGR: 
LGV: 
SGA: 
SGG: 
STB: 
LCB: 
LCZ: 
LCS: 
LCE: 
LCW: 
LCL: 
LRH: 
LRG: 
LRL: 
LRA: 
LRC: 
LPI: 
LPQ: 
ECAS: 
EMU: 
THL: 
CML: 
CPE: 
CPR: 
CDF: 
CDC: 
CDL: 
CDG: 
TIT: 
TOC: 
HOR: 
SCR: 
SSYR: 
SCQ: 
SSAB: 
RXY: 
CGO: 
TAZ: 
SLR: 
IPO: 
STR: 
DSL: 
HAO: 
IAL: 
DPD: 
 » show all
Taxonomy
Reference
1  [PMID:14645248]
  Authors
Sampaio MM, Chevance F, Dippel R, Eppler T, Schlegel A, Boos W, Lu YJ, Rock CO
  Title
Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor.
  Journal
J. Biol. Chem. 279 (2004) 5537-48.
  Sequence
[eco:b0732]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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