| Entry |
|
| Name |
glucan 1,4-alpha-glucosidase;
glucoamylase;
amyloglucosidase;
gamma-amylase;
lysosomal alpha-glucosidase;
acid maltase;
exo-1,4-alpha-glucosidase;
glucose amylase;
gamma-1,4-glucan glucohydrolase;
acid maltase;
1,4-alpha-D-glucan glucohydrolase
|
| Class |
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
 |
| Sysname |
4-alpha-D-glucan glucohydrolase
|
| Reaction(IUBMB) |
Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose
|
| Reaction(KEGG) |
|
| Comment |
Most forms of the enzyme can rapidly hydrolyse 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyse 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides. This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. EC 3.2.1.20 alpha-glucosidase, from mammalian intestine, can catalyse similar reactions.
|
| Pathway |
| Starch and sucrose metabolism | | Metabolic pathways |
|
| Orthology |
| glucoamylase | | maltase-glucoamylase |
|
| Genes |
HSA: | | PTR: | | PPS: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XTR: | | DRE: | | TRU: | | OLA: | | CIN: | | SPU: | | TSP: | | TAD: | | SCE: | | AGO: | | KLA: | | LTH: | | PPA: | | ZRO: | | CGR: | | DHA: | | PIC: | | PGU: | | LEL: | | CAL: | | CTP: | | CDU: | | YLI: | | CLU: | | NCR: | | SMP: | | PAN: | | MGR: | | FGR: | | NHE: | | SSL: | | BFU: | | ANI: | | NFI: | | AFM: | | AOR: | | ANG: | | AFV: | | ACT: | | PCS: | | CIM: | | CPW: | | URE: | | ABE: | | TVE: | | PNO: | | PTE: | | TML: | | SPO: | | CNE: | | CNB: | | PPL: | | LBC: | | MPR: | | CCI: | | SCM: | | UMA: | | MBR: | | PAM: | | PLF: | | PAJ: | | PAQ: | | PSI: | | PSD: | | CJA: | | AVN: | | SON: | | SDN: | | SFR: | | SAZ: | | SBL: | | SBM: | | SBN: | | SBP: | | SBT: | | SBB: | | SLO: | | SHE: | | SHM: | | SHN: | | SWD: | | SWP: | | PSM: | | SDE: | | LPN: | | LPF: | | LPP: | | LPC: | | LPA: | | LPE: | | LLO: | | AFE: | | AFR: | | ACU: | | AFI: | | CVI: | | BPS: | | BPM: | | BPL: | | BPD: | | BPZ: | | BTE: | | VAP: | | NII: | | SLT: | | SUR: | | SCL: | | MLO: | | MCI: | | MOP: | | SMQ: | | SMD: | | ATU: | | AVI: | | AGR: | | RET: | | REC: | | BBT: | | NHA: | | SNO: | | MEA: | | BID: | | MSL: | | RVA: | | CCR: | | CCS: | | CAK: | | CSE: | | BSB: | | AEX: | | GBE: | | RRU: | | RRF: | | TTE: | | TTM: | | TXY: | | TSH: | | MAS: | | SEN: | | AMD: | | AMN: | | AMS: | | CAI: | | PUV: | | ABA: | | ACA: | | ACM: | | GMA: | | TSA: | | TRS: | | CTM: | | CHU: | | CAO: | | ZGA: | | PHM: | | CYP: | | CYH: | | CYJ: | | ANA: | | NPU: | | AVA: | | DLY: | | RCA: | | CAG: | | DGE: | | DGO: | | TSC: | | MSV: | | MMA: | | HMA: | | PTO: | | SSO: | | STO: | | » show all
 |
| Reference |
|
| Authors |
FRENCH D, KNAPP DW. |
| Title |
The maltase of Clostridium acetobutylicum; its specificity range and mode of action. |
| Journal |
J. Biol. Chem. 187 (1950) 463-71. |
| Organism |
Clostridium acetobutylicum [GN: cac] |
| Reference |
|
| Authors |
Brown BI, Brown DH. |
| Title |
The subcellular distribution of enzymes in type II glycogenosis and the occurrence of an oligo-alpha-1,4-glucan glucohydrolase in human tissues. |
| Journal |
Biochim. Biophys. Acta. 110 (1965) 124-33. |
| Organism |
|
| Reference |
|
| Authors |
Jeffrey PL, Brown DH, Brown BI. |
| Title |
Studies of lysosomal alpha-glucosidase. I. Purification and properties of the rat liver enzyme. |
| Journal |
Biochemistry. 9 (1970) 1403-15. |
| Organism |
Rattus norvegicus [GN: rno] |
| Reference |
|
| Authors |
Kelly JJ, Alpers DH. |
| Title |
Properties of human intestinal glucoamylase. |
| Journal |
Biochim. Biophys. Acta. 315 (1973) 113-22. |
| Organism |
|
| Reference |
|
| Authors |
COPELAND WH, MILLER KD. |
| Title |
A blood trans-alpha-glucosylase. |
| Journal |
Biochim. Biophys. Acta. 22 (1956) 193-4. |
| Reference |
|
| Authors |
TSUJISAKA Y, FUKUMOTO J, YAMAMCTO T. |
| Title |
Specificity of crystalline saccharogenic amylase of moulds. |
| Journal |
Nature. 181 (1958) 770-1. |
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9032-08-0 |