KEGG   ENZYME: 3.2.1.96Help
Entry
EC 3.2.1.96                 Enzyme                                 

Name
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase;
N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase;
endo-beta-N-acetylglucosaminidase;
mannosyl-glycoprotein endo-beta-N-acetylglucosamidase;
di-N-acetylchitobiosyl beta-N-acetylglucosaminidase;
endo-beta-acetylglucosaminidase;
endo-beta-(1->4)-N-acetylglucosaminidase;
mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase;
endoglycosidase S;
endo-N-acetyl-beta-D-glucosaminidase;
endo-N-acetyl-beta-glucosaminidase;
endo-beta-N-acetylglucosaminidase D;
endo-beta-N-acetylglucosaminidase F;
endo-beta-N-acetylglucosaminidase H;
endo-beta-N-acetylglucosaminidase L;
glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase;
endoglycosidase H
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase
Reaction(IUBMB)
Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn- structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact
Comment
A group of related enzymes.
History
EC 3.2.1.96 created 1978
Pathway
Other glycan degradation
Orthology
K01227  
mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
K13714  
bifunctional autolysin
Genes
HSA: 
64772(ENGASE)
PTR: 
741918(ENGASE)
PPS: 
100973178(ENGASE)
GGO: 
101150692(ENGASE)
PON: 
100454020(ENGASE)
MCF: 
102133743(ENGASE)
MMU: 
217364(Engase)
RNO: 
303702(Engase)
CGE: 
100754028(Engase)
HGL: 
101711000(Engase)
TUP: 
102480939(ENGASE)
CFA: 
483347(ENGASE)
AML: 
FCA: 
101084586(ENGASE)
PTG: 
102954302(ENGASE)
BTA: 
100847654(ENGASE)
BOM: 
102273299(ENGASE)
PHD: 
102332440(ENGASE)
CHX: 
102187164(ENGASE)
OAS: 
101112239(ENGASE)
SSC: 
100620304(ENGASE)
CFR: 
102521905(ENGASE)
BACU: 
103014781(ENGASE)
LVE: 
103079880(ENGASE)
ECB: 
100057280(ENGASE)
MYB: 
102251109(ENGASE)
MYD: 
102768955(ENGASE)
PALE: 
102895333(ENGASE)
MDO: 
100030963(ENGASE)
SHR: 
100933583(ENGASE)
OAA: 
103167700(ENGASE)
GGA: 
430102(ENGASE)
TGU: 
100218273(ENGASE)
FAB: 
101806132(ENGASE)
APLA: 
101797822(ENGASE)
CLV: 
102091638(ENGASE)
ASN: 
102387987(ENGASE)
AMJ: 
102558652(ENGASE)
CMY: 
102948233(ENGASE)
ACS: 
100563201(engase)
PBI: 
103052676(ENGASE)
XTR: 
100496567(engase)
DRE: 
561239(engase)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102356083(ENGASE)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
725194(GB15391)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG09066(Cbr-eng-1)
BMY: 
LOA: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
POPTR_0008s07300g POPTR_0010s19160g(POPTRDRAFT_880340) POPTR_0010s19170g(POPTRDRAFT_880057)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os05t0346500-01(Os05g0346500)
OBR: 
BDI: 
SBI: 
SORBI_09g016230(SORBIDRAFT_09g016230)
SITA: 
ATR: 
s00153p00087330(AMTR_s00153p00087330)
SMO: 
PPP: 
VCN: 
CME: 
GSL: 
TML: 
PPL: 
LBC: 
MPR: 
CCI: 
SCM: 
UMA: 
MGL: 
MBR: 
DDI: 
DFA: 
PIF: 
TBR: 
TCR: 
LMA: 
LBZ: 
BSU: 
BSU35780(lytD)
BSR: 
I33_3707(lytD)
BSL: 
BSH: 
BSY: 
BSS: 
BST: 
GYO_3937(lytD)
BSO: 
BSN: 
BSQ: 
BSUB: 
BSX: 
C663_3472(lytD)
BLI: 
BL02465(lytD)
BLD: 
BLi03821(lytD)
BLH: 
BAO: 
BAMF_3416(lytD)
BAY: 
BAQ: 
BYA: 
BAMP: 
BAML: 
BAMA: 
RBAU_3430(lytD)
BAMN: 
BASU_3208(lytD)
BAZ: 
BQL: 
LL3_03711(lytD)
BXH: 
BQY: 
MUS_3918(lytD)
BAMI: 
BAE: 
BCL: 
BPU: 
BPUM_3233(lytD)
BCO: 
BCK: 
BJS: 
BLE: 
OIH: 
GTH: 
GMC: 
AXL: 
VIR: 
SAU: 
SA0905(atl)
SAV: 
SAW: 
SAH: 
SAJ: 
SAM: 
MW0936(atl)
SAS: 
SAR: 
SAR1026(atl)
SAC: 
SAX: 
SAA: 
SAO: 
SAE: 
SAD: 
SUU: 
SUV: 
SUH: 
SUE: 
SUJ: 
SUK: 
SUC: 
SUT: 
SUQ: 
SUZ: 
SUD: 
SUX: 
SUW: 
SUG: 
SUF: 
SAUA: 
SAUE: 
SAUN: 
SAUS: 
SAUU: 
SAUZ: 
SAB: 
SUY: 
SAUB: 
SAUM: 
SAUC: 
SAUR: 
SAUI: 
SAUT: 
SAUJ: 
SAUK: 
SAUQ: 
SAUV: 
SAUW: 
SAUX: 
SAUY: 
SEP: 
SER: 
SERP0636(atlE)
SHA: 
SH1911(atl)
SSP: 
SCA: 
SLG: 
SLN: 
SSD: 
SDT: 
SPSE_1762(spsC)
SWA: 
SPAS: 
LIV: 
ESI: 
EAT: 
EAN: 
GYM: 
LLK: 
LLKF_1605(ypcCD)
LLM: 
llmg_1087(acmC) llmg_2165(acmB)
SPZ: 
SPH: 
SPI: 
SPJ: 
SPK: 
SPF: 
SPA: 
SPB: 
SPN: 
SPD: 
SPD_0853(lytB) SPD_1403(lytC)
SPR: 
spr0867(lytB)
SPW: 
SPCG_0941(lytB)
SPX: 
SPG_0889(lytB)
SNE: 
SPV: 
SNM: 
SJJ: 
SPP: 
SNT: 
SNC: 
SNB: 
SNP: 
SNI: 
SNV: 
SNX: 
SND: 
SNU: 
SPNG: 
SPNE: 
SPNU: 
SPNM: 
SPNO: 
SEQ: 
SZO_16140(ndoS)
SEZ: 
Sez_0364(endOF2)
SEU: 
SMB: 
smi_0966(lytB)
SOR: 
SOR_1204(lytB)
STD: 
LPL: 
LPS: 
LBR: 
LBK: 
LRU: 
LRT: 
LBH: 
LBN: 
OOE: 
CNO: 
PAC: 
SRO: 
CHU: 
CHU_1472(flgJ)
 » show all
Taxonomy
Reference
1
  Authors
Chien, S., Weinburg, R., Li, S. and Li, Y.
  Title
Endo-beta-N-acetylglucosaminidase from fig latex.
  Journal
Biochem. Biophys. Res. Commun. 76 (1977) 317-323.
Reference
2  [PMID:4152561]
  Authors
Koide N, Muramatsu T.
  Title
Endo-beta-N-acetylglucosaminidase acting on carbohydrate moieties of glycoproteins. Purification and properties of the enzyme from Diplococcus pneumoniae.
  Journal
J. Biol. Chem. 249 (1974) 4897-904.
Reference
3  [PMID:486141]
  Authors
Pierce RJ, Spik G, Montreuil J.
  Title
Cytosolic location of an endo-N-acetyl-beta-D-glucosaminidase activity in rat liver and kidney.
  Journal
Biochem. J. 180 (1979) 673-76.
Reference
4  [PMID:7378051]
  Authors
Pierce RJ, Spik G, Montreuil J.
  Title
Demonstration and cytosolic location of an endo-N-acetyl-beta-D-glucosaminidase activity towards an asialo-N-acetyl-lactosaminic-type substrate in rat liver.
  Journal
Biochem. J. 185 (1980) 261-4.
Reference
5  [PMID:389]
  Authors
Tai T, Yamashita K, Ogata-Arakawa M, Koide N, Muramatsu T, Iwashita S, Inoue Y, Kobata A.
  Title
Structural studies of two ovalbumin glycopeptides in relation to the endo-beta-N-acetylglucosaminidase specificity.
  Journal
J. Biol. Chem. 250 (1975) 8569-75.
Reference
6  [PMID:4204553]
  Authors
Tarentino AL, Plummer TH Jr, Maley F.
  Title
The release of intact oligosaccharides from specific glycoproteins by endo-beta-N-acetylglucosaminidase H.
  Journal
J. Biol. Chem. 249 (1974) 818-24.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37278-88-9

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