| Entry |
|
|---|
| Name |
NAD(P)+ nucleosidase;
nicotinamide adenine dinucleotide (phosphate) nucleosidase;
triphosphopyridine nucleotidase;
NAD(P) nucleosidase;
NAD(P)ase;
nicotinamide adenine dinucleotide (phosphate) glycohydrolase |
|---|
| Class |
Hydrolases;
Glycosylases;
Hydrolysing N-glycosyl compounds
 |
|---|
| Sysname |
NAD(P)+ glycohydrolase |
|---|
| Reaction(IUBMB) |
NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide [RN:R00102 R00119] |
|---|
| Reaction(KEGG) |
R00102 R00119
 |
|---|
| Substrate |
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Product |
ADP-ribose [CPD:C00301];
nicotinamide [CPD:C00153] |
|---|
| Comment |
Also catalyses transfer of ADP-ribose(P) residues. |
|---|
| Pathway |
PATH: ec00760 Nicotinate and nicotinamide metabolism
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13319302]
ALIVISATOS SG, WOOLLEY DW.
Solubilization and purification of the diphosphopyridine
nucleotidase from beef spleen.
J. Biol. Chem. 219 (1956) 823-32.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13034774]
ZATMAN LJ, KAPLAN NO, COLOWICK SP.
Inhibition of spleen diphosphopyridine nucleotidase by nicotinamide,
an exchange reaction.
J. Biol. Chem. 200 (1953) 197-212.
Neurospora crassa [GN:ncr] |
|---|
Reference
Authors
Title
Journal
|
3
Zatman, L.J., Kaplan, N.O., Colowick, S.P. and Ciotti, M.M.
Formation of the isonicotinic acid hydrazide analog of DPN.
J. Am. Chem. Soc. 75 (1953) 3293-3294. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.2.2.6
IUBMB Enzyme Nomenclature: 3.2.2.6
ExPASy - ENZYME nomenclature database: 3.2.2.6
BRENDA, the Enzyme Database: 3.2.2.6
CAS: 9025-46-1 |
|---|
