KEGG   ENZYME: 3.4.21.20Help
Entry
EC 3.4.21.20                Enzyme                                 

Name
cathepsin G;
chymotrypsin-like proteinase;
neutral proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Specificity similar to chymotrypsin C
Comment
From azurophil granules of polymorphonuclear leukocytes. In peptidase family S1 (trypsin family)
History
EC 3.4.21.20 created 1978
Orthology
K01319  
cathepsin G
Genes
HSA: 
1511(CTSG)
PTR: 
467413(CTSG)
PPS: 
100986490(CTSG)
GGO: 
101132145(CTSG)
PON: 
100436066(CTSG)
MCC: 
716440(CTSG)
MCF: 
102128983(CTSG)
MMU: 
13035(Ctsg)
RNO: 
290257(Ctsg) 408207(Mcpt8l3) 408240(Mcpt8l2)
CGE: 
HGL: 
TUP: 
102471354(CTSG)
AML: 
FCA: 
101098719(CTSG)
BTA: 
505658(CTSG) 509956(CTSG)
BOM: 
PHD: 
CHX: 
SSC: 
CFR: 
102517784(CTSG)
ECB: 
100053921(CTSG)
MYB: 
GGA: 
426049(CTSG)
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
ACS: 
 » show all
Taxonomy
Reference
1  [PMID:7341917]
  Authors
Barrett AJ.
  Title
Cathepsin G.
  Journal
Methods. Enzymol. 80 Pt C (1981) 561-5.
Reference
2  [PMID:4016099]
  Authors
Tanaka T, Minematsu Y, Reilly CF, Travis J, Powers JC.
  Title
Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors.
  Journal
Biochemistry. 24 (1985) 2040-7.
  Organism
Homo sapiens [GN:hsa]
Reference
3  [PMID:2569462]
  Authors
Hohn PA, Popescu NC, Hanson RD, Salvesen G, Ley TJ.
  Title
Genomic organization and chromosomal localization of the human cathepsin G gene.
  Journal
J. Biol. Chem. 264 (1989) 13412-9.
  Organism
Homo sapiens [GN:hsa]
  Sequence
[hsa:1511]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
56645-49-9

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