KEGG   ENZYME: 3.4.21.80Help
Entry
EC 3.4.21.80                Enzyme                                 

Name
streptogrisin A;
Streptomyces griseus protease A;
protease A;
proteinase A;
Streptomyces griseus proteinase A;
Streptomyces griseus serine proteinase 3;
Streptomyces griseus serine proteinase A
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Serine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins with specificity similar to chymotrypsin
Comment
From Streptomyces griseus. A component of Pronase, in family S1 (trypsin family). Not inhibited by Tos-Phe-CH2Cl or ovomucoid
History
EC 3.4.21.80 created 1993
Reference
1  [PMID:5575653]
  Authors
Johnson P, Smillie LB.
  Title
The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus.
  Journal
Can. J. Biochem. 49 (1971) 548-62.
  Organism
Streptomyces griseus
Reference
2  [PMID:119870]
  Authors
Sielecki AR, Hendrickson WA, Broughton CG, Delbaere LT, Brayer GD, James MN.
  Title
Protein structure refinement: Streptomyces griseus serine protease A at 1.8 A resolution.
  Journal
J. Mol. Biol. 134 (1979) 781-804.
  Organism
Streptomyces griseus
  Sequence
[sgr:SGR_370]
Reference
3  [PMID:6783761]
  Authors
James MN, Sielecki AR, Brayer GD, Delbaere LT, Bauer CA.
  Title
Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis.
  Journal
J. Mol. Biol. 144 (1980) 43-88.
  Organism
Streptomyces griseus
Reference
4  [PMID:3892018]
  Authors
Delbaere LT, Brayer GD.
  Title
The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates.
  Journal
J. Mol. Biol. 183 (1985) 89-103.
  Organism
Streptomyces griseus
Reference
5  [PMID:3112129]
  Authors
Henderson G, Krygsman P, Liu CJ, Davey CC, Malek LT.
  Title
Characterization and structure of genes for proteases A and B from Streptomyces griseus.
  Journal
J. Bacteriol. 169 (1987) 3778-84.
  Organism
Streptomyces griseus
  Sequence
[sgr:SGR_370]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
55326-50-6

DBGET integrated database retrieval system