KEGG   ENZYME: 3.4.22.10Help
Entry
EC 3.4.22.10                Enzyme                                 
Name
streptopain;
Streptococcus peptidase A;
streptococcal cysteine proteinase;
Streptococcus protease
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Preferential cleavage with hydrophobic residues at P2, P1 and P1'
Comment
From the bacterium, group A Streptococcus. Formed from the proenzyme by limited proteolysis. Type example of peptidase family C10.
Orthology
K01364  
streptopain
Genes
SPY: 
SPy_2039(speB)
SPZ: 
SPM: 
SPG: 
SPS: 
SPH: 
SPI: 
SPJ: 
SPK: 
SPF: 
SpyM51698(speB)
SPA: 
M6_Spy1735
SPB: 
M28_Spy1721(speB)
SOZ: 
Spy49_1690c(speB)
FBR: 
FBFL15_0520
 » show all
Taxonomy
Reference
1
  Authors
Elliott, S.D. and Liu, T.-Y.
  Title
Streptococcal proteinase.
  Journal
Methods Enzymol. 19 (1970) 252-261.
Reference
2
  Authors
Liu, T.-Y. and Elliott, S.D.
  Title
Streptococcal proteinase.
  Journal
In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., Academic Press, New York, 1971, p. 609-647.
Reference
3  [PMID:1270417]
  Authors
Tai JY, Kortt AA, Liu TY, Elliott SD.
  Title
Primary structure of streptococcal proteinase. III. Isolation of cyanogen bromide peptides: complete covalent structure of the polypeptide chain.
  Journal
J. Biol. Chem. 251 (1976) 1955-9.
  Organism
Streptococcus sp.
Reference
4  [PMID:6381494]
  Authors
Lo SS, Fraser BA, Liu TY.
  Title
The mixed disulfide in the zymogen of streptococcal proteinase. Characterization and implication for its biosynthesis.
  Journal
J. Biol. Chem. 259 (1984) 11041-5.
  Organism
Streptococcus sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9025-51-8
DBGET integrated database retrieval system