KEGG   ENZYME: 3.4.22.14Help
Entry
EC 3.4.22.14                Enzyme                                 

Name
actinidain;
actinidin;
Actinidia anionic protease;
proteinase A2 of Actinidia chinensis
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Similar to that of papain
Comment
From the kiwi fruit or Chinese gooseberry (Actinidia chinensis). In peptidase family C1 (papain family)
History
EC 3.4.22.14 created 1978
Reference
1  [PMID:7002215]
  Authors
Baker EN, Boland MJ, Calder PC, Hardman MJ.
  Title
The specificity of actinidin and its relationship to the structure of the enzyme.
  Journal
Biochim. Biophys. Acta. 616 (1980) 30-4.
Reference
2  [PMID:3889350]
  Authors
Kamphuis IG, Drenth J, Baker EN.
  Title
Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain.
  Journal
J. Mol. Biol. 182 (1985) 317-29.
  Organism
Actinidia chinensis, Carica papaya
Reference
3
  Authors
Baker, E.N. and Drenth, J.
  Title
The thiol proteases: stucture and mechanism.
  Journal
In: Jurnak, F.A. and McPherson, A. (Eds.), Biological Macromolecules and Assemblies: Active Sites of Enzymes, vol. 3, John Wiley and Sons, New York, 1987, p. 314-368.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
39279-27-1

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