KEGG   ENZYME: 3.4.22.16Help
Entry
EC 3.4.22.16                Enzyme                                 

Name
cathepsin H;
cathepsin B3;
benzoylarginine-naphthylamide (BANA) hydrolase (obsolete);
cathepsin Ba, aleurain;
N-benzoylarginine-beta-naphthylamide hydrolase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg! bonds) as well as an endopeptidase
Comment
Present in lysosomes of mammalian cells. In peptidase family C1 (papain family)
History
EC 3.4.22.16 created 1981, modified 1989
Orthology
K01366  
cathepsin H
Genes
HSA: 
1512(CTSH)
PTR: 
740462(CTSH)
PPS: 
100994578(CTSH)
GGO: 
101144312(CTSH)
PON: 
100460564(CTSH)
MCC: 
711437(CTSH)
MCF: 
102115935(CTSH)
MMU: 
13036(Ctsh)
RNO: 
25425(Ctsh)
CGE: 
HGL: 
101700582(Ctsh)
TUP: 
102483972(CTSH)
CFA: 
479065(CTSH)
AML: 
FCA: 
101092687(CTSH)
BTA: 
510524(CTSH)
BOM: 
102281958(CTSH)
PHD: 
102321273(CTSH)
CHX: 
102170638(CTSH)
SSC: 
396969(CTSH)
CFR: 
102524291(CTSH)
ECB: 
100059835(CTSH)
MYD: 
102754763(CTSH)
PALE: 
102897634(CTSH)
MDO: 
SHR: 
100926518(CTSH)
GGA: 
770109(CTSH)
MGP: 
TGU: 
100232804(CTSH)
FAB: 
101811077(CTSH)
PHI: 
102108387(CTSH)
APLA: 
101804912(CTSH)
FPG: 
101922144(CTSH)
FCH: 
102057998(CTSH)
CLV: 
102087477(CTSH)
ASN: 
102384797(CTSH)
PSS: 
102458148(CTSH)
CMY: 
102938471(CTSH)
DRE: 
324818(ctsh)
TRU: 
MZE: 
XMA: 
LCM: 
102358878(CTSH)
BFO: 
CIN: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os09t0442300-01(Os09g0442300)
OBR: 
BDI: 
SBI: 
SORBI_02g025920(SORBIDRAFT_02g025920)
ZMA: 
542451(ccp2)
SITA: 
ATR: 
s00024p00241140(AMTR_s00024p00241140)
SMO: 
PPP: 
TET: 
PIF: 
EHX: 
GTT: 
 » show all
Taxonomy
Reference
1  [PMID:7043200]
  Authors
Barrett AJ, Kirschke H.
  Title
Cathepsin B, Cathepsin H, and cathepsin L.
  Journal
Methods. Enzymol. 80 Pt C (1981) 535-61.
Reference
2  [PMID:3663163]
  Authors
Bromme D, Bescherer K, Kirschke H, Fittkau S.
  Title
Enzyme-substrate interactions in the hydrolysis of peptides by cathepsins B and H from rat liver.
  Journal
Biochem. J. 245 (1987) 381-5.
  Organism
Rattus norvegicus
Reference
3  [PMID:2849458]
  Authors
Fuchs R, Machleidt W, Gassen HG.
  Title
Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H.
  Journal
Biol. Chem. Hoppe. Seyler. 369 (1988) 469-75.
  Organism
Homo sapiens
  Sequence
[hsa:1512]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
60748-73-4

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