KEGG   ENZYME: 3.4.22.30Help
Entry
EC 3.4.22.30                Enzyme                                 

Name
caricain;
papaya peptidase A;
papaya peptidase II;
papaya proteinase ;
papaya proteinase III;
papaya proteinase 3;
proteinase omega;
papaya proteinase A;
chymopapain S;
Pp
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain
Comment
From papaya plant, Carica papaya. In peptidase family C1 (papain family)
History
EC 3.4.22.30 created 1992
Reference
1  [PMID:6043136]
  Authors
Schack P.
  Title
Fractionation of proteolytic enzymes of dried papaya latex. Isolation and preliminary characterization of a new proteolytic enzyme.
  Journal
C. R. Trav. Lab. Carlsberg. 36 (1967) 67-83.
Reference
2  [PMID:240390]
  Authors
Robinson GW.
  Title
Isolation and characterization of papaya peptidase A from commercial chymopapain.
  Journal
Biochemistry. 14 (1975) 3695-700.
Reference
3  [PMID:6383350]
  Authors
Polgar L.
  Title
Problems of classification of papaya latex proteinases.
  Journal
Biochem. J. 221 (1984) 555-6.
Reference
4  [PMID:4015629]
  Authors
Brocklehurst K, Salih E, McKee R, Smith H.
  Title
Fresh non-fruit latex of Carica papaya contains papain, multiple forms of chymopapain A and papaya proteinase omega.
  Journal
Biochem. J. 228 (1985) 525-7.
Reference
5  [PMID:3919769]
  Authors
Zucker S, Buttle DJ, Nicklin MJ, Barrett AJ.
  Title
The proteolytic activities of chymopapain, papain, and papaya proteinase III.
  Journal
Biochim. Biophys. Acta. 828 (1985) 196-204.
Reference
6  [PMID:3063283]
  Authors
Dubois T, Kleinschmidt T, Schnek AG, Looze Y, Braunitzer G.
  Title
The thiol proteinases from the latex of Carica papaya L. II. The primary structure of proteinase omega.
  Journal
Biol. Chem. Hoppe. Seyler. 369 (1988) 741-54.
  Sequence
[up:P10056]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
39307-22-7

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