KEGG   ENZYME: 3.4.22.6Help
Entry
EC 3.4.22.6                 Enzyme                                 

Name
chymopapain;
chymopapain A;
chymopapain B;
chymopapain S
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Similar to that of papain
Comment
The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family).
History
EC 3.4.22.6 created 1961 as EC 3.4.4.11, transferred 1972 to EC 3.4.22.6
Reference
1
  Authors
Brocklehurst, K., Willenbrock, F. and Salih, E.
  Title
Cysteine proteinases.
  Journal
In: Neuberger, A. and Brocklehurst, K. (Eds.), New Comprehensive Biochemistry: Hydrolytic Enzymes, Elsevier, Amsterdam, 1987, p. 39-158.
Reference
2  [PMID:2500950]
  Authors
Jacquet A, Kleinschmidt T, Schnek AG, Looze Y, Braunitzer G.
  Title
The thiol proteinases from the latex of Carica papaya L. III. The primary structure of chymopapain.
  Journal
Biol. Chem. Hoppe. Seyler. 370 (1989) 425-34.
  Sequence
[up:P14080]
Reference
3  [PMID:2085414]
  Authors
Buttle DJ, Dando PM, Coe PF, Sharp SL, Shepherd ST, Barrett AJ.
  Title
The preparation of fully active chymopapain free of contaminating proteinases.
  Journal
Biol. Chem. Hoppe. Seyler. 371 (1990) 1083-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9001-09-6

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