KEGG   ENZYME: 3.4.22.71Help
Entry
EC 3.4.22.71                Enzyme                                 

Name
sortase B;
SrtB
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
The enzyme catalyses a cell wall sorting reaction in which a surface protein with a sorting signal containing a NXTN motif is cleaved. The resulting threonine carboxyl end of the protein is covalently attached to a pentaglycine cross-bridge of peptidoglycan.
Comment
In peptidase family C60.
History
EC 3.4.22.71 created 2009
Reference
1  [PMID:14725770]
  Authors
Zong Y, Mazmanian SK, Schneewind O, Narayana SV
  Title
The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall.
  Journal
Structure. 12 (2004) 105-12.
Reference
2  [PMID:15028680]
  Authors
Bierne H, Garandeau C, Pucciarelli MG, Sabet C, Newton S, Garcia-del Portillo F, Cossart P, Charbit A
  Title
Sortase B, a new class of sortase in Listeria monocytogenes.
  Journal
J. Bacteriol. 186 (2004) 1972-82.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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