KEGG   ENZYME: 3.4.24.19Help
Entry
EC 3.4.24.19                Enzyme                                 

Name
procollagen C-endopeptidase;
procollagen C-terminal proteinase;
carboxyprocollagen peptidase;
procollagen C-terminal peptidase;
procollagen C-proteinase;
procollagen C-terminal proteinase;
procollagen carboxypeptidase;
procollagen carboxy-terminal proteinase;
procollagen peptidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Cleavage of the C-terminal propeptide at Ala!Asp in type I and II procollagens and at Arg!Asp in type III
Comment
A 100 kDa endopeptidase the activity of which is increased by Ca2+ and by an enhancer glycoprotein. In peptidase family M12 (astacin family)
History
EC 3.4.24.19 created 1992
Orthology
K05502  
bone morphogenetic protein 1
Genes
HSA: 
649(BMP1)
PTR: 
464042(BMP1)
PPS: 
100979179(BMP1)
GGO: 
101145590(BMP1)
PON: 
100453093(BMP1)
MCC: 
707596(BMP1)
MCF: 
102116822(BMP1)
MMU: 
12153(Bmp1)
RNO: 
83470(Bmp1)
CGE: 
100751120(Bmp1)
HGL: 
101713810(Bmp1)
TUP: 
102480045(BMP1)
CFA: 
100856514(BMP1)
AML: 
100477539(BMP1)
FCA: 
101093350(BMP1)
BTA: 
510360(BMP1)
BOM: 
102266088(BMP1)
PHD: 
102317127(BMP1)
CHX: 
102179476(BMP1)
SSC: 
100156461(BMP1)
CFR: 
102521071(BMP1)
ECB: 
100056914(BMP1)
MYB: 
102239069(BMP1)
MDO: 
SHR: 
100932831(BMP1)
PHI: 
102099474(BMP1)
FPG: 
101918385(BMP1)
ASN: 
102376631(BMP1)
PSS: 
102460646(BMP1)
XLA: 
397872(bmp1-b) 399093(bmp1-a)
XTR: 
733960(bmp1)
DRE: 
572452(bmp1a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102357697(BMP1)
SPU: 
373360(BMP1)
 » show all
Taxonomy
Reference
1  [PMID:3905801]
  Authors
Hojima Y, van der Rest M, Prockop DJ.
  Title
Type I procollagen carboxyl-terminal proteinase from chick embryo tendons. Purification and characterization.
  Journal
J. Biol. Chem. 260 (1985) 15996-6003.
  Organism
Gallus gallus [GN:gga]
Reference
2  [PMID:2689170]
  Authors
Kessler E, Adar R.
  Title
Type I procollagen C-proteinase from mouse fibroblasts. Purification and demonstration of a 55-kDa enhancer glycoprotein.
  Journal
Eur. J. Biochem. 186 (1989) 115-21.
  Organism
Mus musculus [GN:mmu]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
68651-95-6

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