KEGG   ENZYME: 3.4.24.66Help
Entry
EC 3.4.24.66                Enzyme                                 

Name
choriolysin L;
teleost hatching enzyme (component);
low choriolytic enzyme (LCE)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of the inner layer of fish egg envelope. Also hydrolysis of casein and small molecule substrates such as succinyl-Leu-Leu-Val-Tyr!7-(4-methyl)coumarylamide
Comment
Known from the teleost fish Oryzias latipes (medaka). Efficient dissolution of the egg membrane requires concerted action with choriolysin H. A 24 kDa peptidase family M12 (astacin family)
History
EC 3.4.24.66 created 1995
Orthology
K18542  
choriolysin L
Genes
TRU: 
777973(fglce)
MZE: 
OLA: 
Taxonomy
Reference
1
  Authors
Yasumasu, S., Iuchi, I. and Yamagami, K.
  Title
Medaka hatching enzyme consists of two kinds of proteases which act cooperatively.
  Journal
Zool. Sci. 5 (1988) 191-195.
Reference
2  [PMID:2656665]
  Authors
Yasumasu S, Iuchi I, Yamagami K.
  Title
Isolation and some properties of low choriolytic enzyme (LCE), a component of the hatching enzyme of the teleost, Oryzias latipes.
  Journal
J. Biochem. (Tokyo). 105 (1989) 212-8.
Reference
3  [PMID:1730389]
  Authors
Yasumasu S, Katow S, Hamazaki TS, Iuchi I, Yamagami K.
  Title
Two constituent proteases of a teleostean hatching enzyme: concurrent syntheses and packaging in the same secretory granules in discrete arrangement.
  Journal
Dev. Biol. 149 (1992) 349-56.
Reference
4  [PMID:1397682]
  Authors
Yasumasu S, Yamada K, Akasaka K, Mitsunaga K, Iuchi I, Shimada H, Yamagami K.
  Title
Isolation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development.
  Journal
Dev. Biol. 153 (1992) 250-8.
  Sequence
[ola:100049451]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
177529-15-6

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