KEGG   ENZYME: 3.5.1.10Help
Entry
EC 3.5.1.10                 Enzyme                                 
Name formyltetrahydrofolate deformylase
Class Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname 10-formyltetrahydrofolate amidohydrolase
Reaction(IUBMB) 10-formyltetrahydrofolate + H2O = formate + tetrahydrofolate
[RN:R00944]
Reaction(KEGG) R00944
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Substrate 10-formyltetrahydrofolate [CPD:C00234];
H2O [CPD:C00001]
Product formate [CPD:C00058];
tetrahydrofolate [CPD:C00101]
Pathway PATH: ec00630  Glyoxylate and dicarboxylate metabolism
PATH: ec00670  One carbon pool by folate
Orthology KO: K01433  formyltetrahydrofolate deformylase
Genes ATH: AT4G17360
POP: POPTR_646120
RCU: RCOM_1388550
OSA: 4331294(Os03g0102100)
SBI: SORBI_01g050510(SORBIDRAFT_01g050510)
ZMA: 100286111
PPP: PHYPADRAFT_140138
NCR: NCU09911
MGR: MGG_08008
FGR: FG08971.1
ANI: AN0495.2
AFM: AFUA_6G11620
AOR: AO090023000412
ANG: An01g11650
AFV: AFLA_108270
PCS: Pc20g01960
NFI: NFIA_057310
SSL: SS1G_06272
UMA: UM00231.1
ECO: b1232(purU)
ECJ: JW1220(purU)
ECD: ECDH10B_1292(purU)
EBW: BWG_1058(purU)
ECE: Z2008(purU)
ECS: ECs1734(purU)
ECF: ECH74115_1717(purU)
ETW: ECSP_1624(purU)
ECG: E2348C_1359(purU)
ECC: c1696(purU)
ECI: UTI89_C1428(purU)
ECP: ECP_1279(purU)
ECV: APECO1_346(purU)
ECW: EcE24377A_1381(purU)
ECX: EcHS_A1340(purU)
ECM: EcSMS35_1909(purU)
ECY: ECSE_1282(purU)
ECL: EcolC_2395(purU)
ECK: EC55989_1327(purU)
ECQ: ECED1_1383(purU)
ECR: ECIAI1_1252(purU)
ECT: ECIAI39_1567(purU)
ECZ: ECS88_1300(purU)
EUM: ECUMN_1529(purU)
ELF: LF82_1786(purU)
EBL: B21_01218(purU)
EBD: ECBD_2390
EBR: ECB_01208(purU)
EOH: ECO103_1334(purU)
EOI: ECO111_1560(purU)
EOJ: ECO26_1744(purU)
EFE: EFER_1723(purU)
STY: STY1294(purU)
STT: t1667(purU)
SPT: SPA1122(purU)
SEK: SSPA1041(purU)
SPQ: SPAB_01485
SEI: SPC_1973(purU)
SEC: SC1751(purU)
SEH: SeHA_C1946(purU)
SEE: SNSL254_A1883(purU)
SEW: SeSA_A1889(purU)
SEA: SeAg_B1389(purU)
SED: SeD_A1572(purU)
SEG: SG1360(purU)
SET: SEN1280(purU)
SES: SARI_01197(purU)
STM: STM1756(purU)
YPK: y2150(purU)
YPM: YP_1970(purU)
YPA: YPA_1529(purU)
YPN: YPN_1638(purU)
YPG: YpAngola_A2334(purU)
YPP: YPDSF_0963(purU)
YPS: YPTB2097(purU)
YPI: YpsIP31758_1971(purU)
YPY: YPK_2080(purU)
YPB: YPTS_2163(purU)
YEN: YE2247(purU)
SFL: SF1232(purU)
SFX: S1318(purU)
SFV: SFV_1245(purU)
SSN: SSON_1947(purU)
SBO: SBO_1837(purU)
SBC: SbBS512_E1397(purU)
SDY: SDY_1284(purU)
ECA: ECA2333(purU)
PCT: PC1_1976
PWA: Pecwa_2277
ETA: ETA_15730(purU)
PLU: plu2504(purU)
PAY: PAU_02022(purU)
WBR: WGLp370(purU)
SGL: SG1364(purU)
ENT: Ent638_2311(purU)
ESA: ESA_01530(purU)
CTU: Ctu_23920(purU)
KPN: KPN_02206(purU)
KPE: KPK_2102(purU)
KPU: KP1_3319(purU)
CKO: CKO_01310(purU)
SPE: Spro_2713(purU)
PMR: PMI1493(purU)
EIC: NT01EI_1659
ETR: ETAE_1499(purU)
HDE: HDEF_2061(purU)
DDA: Dd703_1962
DDC: Dd586_2151
DZE: Dd1591_2204
HIN: HI1588(purU)
HIT: NTHI1463(purU)
HIP: CGSHiEE_05545(purU)
HIQ: CGSHiGG_10175(purU)
HAP: HAPS_1120(purU)
HSO: HS_0786(purU)
HSM: HSM_1253(purU)
PMU: PM0873(purU)
MSU: MS1323(purU)
ASU: Asuc_1036(purU)
AAP: NT05HA_0883
AAT: D11S_1446
XFA: XF1831(purU)
XFT: PD1036(purU)
XFM: Xfasm12_1192(purU)
XFN: XfasM23_1100(purU)
XCC: XCC0310(purU)
XCB: XC_0322(purU)
XCA: xccb100_0335(purU)
XCV: XCV0333(purU)
XAC: XAC0324(purU)
XOO: XOO4342(purU)
XOM: XOO_4092(purU)
XOP: PXO_03765(purU)
SML: Smlt0255(purU)
SMT: Smal_0213(purU)
VCH: VC1992(purU)
VCO: VC0395_A1577(purU)
VCM: VCM66_1916(purU)
VCJ: VCD_002376
VVU: VV1_0143(purU)
VVY: VV1046(purU)
VPA: VP0864(purU)
VHA: VIBHAR_01373(purU)
VSP: VS_2228(purU)
VEX: VEA_004096
VFI: VF_1714(purU)
VFM: VFMJ11_1840(purU)
VSA: VSAL_I0912(purU)
PPR: PBPRA1066(purU) PBPRA1448
PAE: PA4314(purU) PA5420(purU2)
PAU: PA14_56060(purU) PA14_71530(purU2)
PAP: PSPA7_4882(purU) PSPA7_6208(purU1)
PAG: PLES_46921(purU) PLES_58151(purU2)
PPU: PP_0327(purU-1) PP_1367(purU) PP_1943(purU)
PPF: Pput_0349 Pput_4356
PPG: PputGB1_0350 PputGB1_2106 PputGB1_4447(purU)
PPW: PputW619_1007(purU) PputW619_4880
PST: PSPTO_0456(purU-1) PSPTO_2454(purU-2) PSPTO_4314(purU-3)
PSB: Psyr_2226 Psyr_4018(purU) Psyr_4717
PSP: PSPPH_2960(purU1) PSPPH_4024(purU) PSPPH_4755(purU3)
PFL: PFL_4786(purU) PFL_5724(purU)
PFO: Pfl01_4436(purU) Pfl01_5203
PFS: PFLU2321(purU1) PFLU2332(purU2) PFLU4938 PFLU5647(purU)
PEN: PSEEN1152(purU) PSEEN5157(purU-1)
PMY: Pmen_3312(purU) Pmen_3457 Pmen_3470 Pmen_4127
PSA: PST_1165(purU)
CJA: CJA_1602(purU)
AVN: Avin_38280(purU)
PCR: Pcryo_1987
PRW: PsycPRwf_0414
ACI: ACIAD0505(purU1) ACIAD2554(purU)
ACB: A1S_0451
ABM: ABSDF3060(purU1)
ABY: ABAYE3322(purU1)
ABC: ACICU_00461
ABN: AB57_0534(purU)
ABB: ABBFA_003083(purU)
SON: SO_1624(purU)
SDN: Sden_1549(purU)
SFR: Sfri_1265(purU)
SAZ: Sama_1134(purU)
SBL: Sbal_1445(purU)
SBM: Shew185_1440(purU)
SBN: Sbal195_1476(purU)
SBP: Sbal223_2907(purU)
SLO: Shew_2640(purU)
SPC: Sputcn32_1343(purU)
SSE: Ssed_3166(purU)
SHE: Shewmr4_2647(purU)
SHM: Shewmr7_2714(purU)
SHN: Shewana3_2821(purU)
SHW: Sputw3181_2760(purU)
SHL: Shal_2986
SWD: Swoo_3286(purU)
SWP: swp_3528
CPS: CPS_2482(purU1) CPS_3620(purU) CPS_4036(purU) CPS_4357(purU4)
PHA: PSHAa0701(purU)
PAT: Patl_0486
SDE: Sde_2376
MAQ: Maqu_1020(purU)
AMC: MADE_00467
PIN: Ping_1027(purU)
TTU: TERTU_2956(purU)
FTN: FTN_0629(purU)
FPH: Fphi_0213
TCX: Tcr_1352 Tcr_2051(purU)
NOC: Noc_1789(purU)
AEH: Mlg_2099
TGR: Tgr7_1693
HCH: HCH_04985(purU)
CSA: Csal_1002 Csal_2073(purU)
ABO: ABO_1563(purU)
MMW: Mmwyl1_1740 Mmwyl1_2756
AHA: AHA_1310(purU)
ASA: ASA_1292(purU)
TAU: Tola_0638
CVI: CV_1926(purU)
LHK: LHK_01017(purU)
RSO: RSc1106(purU) RSc1873(purU) RSp0065(purU2)
RPI: Rpic_2074(purU)
RPF: Rpic12D_1752
REU: Reut_A2211(purU) Reut_B4812
REH: H16_A2505(purU) H16_B1956(purU)
RME: Rmet_2236(purU)
CTI: RALTA_A2008(purU)
BMA: BMA3097(purU) BMAA0482(purU-2)
BMV: BMASAVP1_0699(purU-2) BMASAVP1_A0066(purU)
BML: BMA10229_0995(purU-2) BMA10229_A1524(purU)
BMN: BMA10247_2952(purU) BMA10247_A1968(purU-2)
BPS: BPSL0543(purU) BPSS0558
BPM: BURPS1710b_0777(purU) BURPS1710b_A2119(purU)
BPL: BURPS1106A_0607(purU) BURPS1106A_A0751(purU)
BPD: BURPS668_0591(purU) BURPS668_A0839(purU)
BPR: GBP346_A0518(purU_1)
BTE: BTH_I0496(purU) BTH_II1857(purU-2)
BVI: Bcep1808_2886(purU) Bcep1808_3412
BUR: Bcep18194_A6111(purU) Bcep18194_B0585
BCN: Bcen_2167(purU) Bcen_3294
BCH: Bcen2424_2781(purU) Bcen2424_5074
BCM: Bcenmc03_2792(purU) Bcenmc03_5211
BCJ: BCAL0823(purU) BCAM2315(purU)
BAM: Bamb_2841(purU) Bamb_4486
BAC: BamMC406_2699(purU) BamMC406_5011
BMU: Bmul_0534(purU) Bmul_3565
BMJ: BMULJ_02725(purU) BMULJ_04952(purU)
BXE: Bxe_A4112(purU) Bxe_B1575
BPH: Bphy_0336(purU) Bphy_3292(purU) Bphy_5913(purU)
BPY: Bphyt_0606(purU) Bphyt_5073
BGL: bglu_1g31110 bglu_2g05930
PNU: Pnuc_1153(purU)
BPE: BP2514(purU) BP3254(purU)
BPA: BPP3501(purU) BPP3610(purU)
BBR: BB4045(purU)
BPT: Bpet0857(purU)
BAV: BAV2820(purU)
RFR: Rfer_0609(purU)
POL: Bpro_0438(purU)
PNA: Pnap_0297(purU)
AAV: Aave_0648(purU)
AJS: Ajs_0428(purU)
VEI: Veis_0706(purU)
DAC: Daci_1081(purU)
DIA: Dtpsy_0419
VAP: Vapar_4789
CTT: CtCNB1_4373
MPT: Mpe_A3546
HAR: HEAR0993(purU)
MMS: mma_1130(purU)
LCH: Lcho_0174(purU) Lcho_1303 Lcho_3290(purU)
EBA: ebA3467(purU)
AZO: azo3742(purU)
DAR: Daro_0056(purU)
TMZ: Tmz1t_0584
TBD: Tbd_1977
MFA: Mfla_2434
MMB: Mmol_2278
MEI: Msip34_2601
APP: CAP2UW1_3896
HPY: HP1434
HPJ: jhp1327(purU)
HPA: HPAG1_1360
HPS: HPSH_07305
HPG: HPG27_1355
HPP: HPP12_1409(purU)
HPB: HELPY_1403(purU)
HHE: HH1691(purU)
HAC: Hac_1657(purU)
WSU: WS1475(purU)
TDN: Suden_1098
CJE: Cj0790(purU)
CJR: CJE0881(purU)
CJJ: CJJ81176_0811(purU)
CJU: C8J_0741(purU)
CJD: JJD26997_1220(purU)
CFF: CFF8240_0822(purU)
CCV: CCV52592_1370(purU)
CHA: CHAB381_1249(purU)
ABU: Abu_1077(purU)
SDL: Sdel_1512
NIS: NIS_0729(purU)
SUN: SUN_1704(purU)
NAM: NAMH_1252(purU)
DVU: DVU1540(purU)
DVL: Dvul_1591(purU)
DVM: DvMF_0189(purU)
DMA: DMR_12050(purU)
DSA: Desal_2950
DRT: Dret_0523
ADE: Adeh_2012(purU)
ACP: A2cp1_1951
AFW: Anae109_1795(purU)
ANK: AnaeK_1866(purU)
SCL: sce0494(purU)
MES: Meso_0452
SME: SMa2141(purU3) SMc03205(purU1) SMc04154(purU)
SMD: Smed_2830 Smed_3310(purU) Smed_6004
ATU: Atu2464(purU) Atu4231(purU) Atu4315(purU)
ATC: AGR_C_4474(purU) AGR_L_1098 AGR_L_1261
ARA: Arad_0389(purU) Arad_8369(purU)
AVI: Avi_6011(purU)
RET: RHE_CH00225(purU) RHE_PE00417(purUe)
REC: RHECIAT_CH0000268(purU) RHECIAT_CH0002062(purU)
     RHECIAT_PA0000333(purUa)
RLE: RL0233(purU) pRL110553(purU)
RLT: Rleg2_1628(purU) Rleg2_4206(purU) Rleg2_5642
RLG: Rleg_4496 Rleg_6579
RHI: NGR_b16610(purU1) NGR_b17070(purU2) NGR_c14420(purU4)
     NGR_c29940(purU3)
LAS: CLIBASIA_04050
BME: BMEII0387(purU)
BMI: BMEA_B0891(purU)
BMF: BAB2_0326(purU)
BMB: BruAb2_0324(purU)
BMC: BAbS19_II03090(purU)
BMS: BRA0909(purU)
BMT: BSUIS_B0902(purU)
BOV: BOV_A0852(purU)
BCS: BCAN_B0928(purU)
BMR: BMI_II903(purU)
OAN: Oant_1458(purU)
BJA: bll5955(purU)
BRA: BRADO5257(purU)
BBT: BBta_5709(purU)
RPA: RPA4032(purU)
RPB: RPB_1145 RPB_1577(purU)
RPC: RPC_4164(purU)
RPD: RPD_1583(purU)
RPE: RPE_4219(purU)
RPT: Rpal_4562(purU)
NWI: Nwi_2382(purU)
OCA: OCAR_5315(purU)
XAU: Xaut_4704(purU)
AZC: AZC_1376 AZC_1492
MCH: Mchl_5699
CCR: CC_3630(purU)
CCS: CCNA_03745
CAK: Caul_1110(purU) Caul_2361
PZU: PHZ_c1081(purU) PHZ_c2415(purU)
RSP: RSP_0944(purU)
RSH: Rsph17029_2603(purU)
RSQ: Rsph17025_2971(purU)
RSK: RSKD131_2334
PDE: Pden_2613(purU)
DSH: Dshi_2111(purU)
HNE: HNE_0787(purU)
HBA: Hbal_0897
NAR: Saro_2862(purU)
SWI: Swit_0941(purU) Swit_1157
ELI: ELI_14550(purU)
GOX: GOX2073(purU)
ACR: Acry_2764(purU)
GDI: GDI_1169
GDJ: Gdia_1883
APT: APA01_05510
RRU: Rru_A0556(purU)
RCE: RC1_0137(purU)
MAG: amb3572
BSU: BSU13110(ykkE)
BHA: BH3265(purU)
BLI: BL03753(purU)
BLD: BLi01411(purU)
BCL: ABC2781(purU)
BAY: RBAM_012920(purU)
BPU: BPUM_1205(purU)
OIH: OB2693(purU)
GKA: GK1736(purU)
GTN: GTNG_1633(purU)
GWC: GWCH70_1631
GYM: GYMC10_5223
GYC: GYMC61_2543
AFL: Aflv_1435(purU)
SSP: SSP0951
BBE: BBR47_49590(purU)
PJD: Pjdr2_1253
AAC: Aaci_2419
MTU: Rv2964(purU)
MTC: MT3041(purU)
MRA: MRA_2991(purU)
MTF: TBFG_12978(purU)
MTB: TBMG_01007(TBMG_01007.1)
MBO: Mb2988(purU)
MBB: BCG_2985(purU)
MBT: JTY_2980(purU)
MSM: MSMEG_2200(purU)
MVA: Mvan_1265(purU)
MGI: Mflv_5090(purU)
MAB: MAB_1306(purU)
MMI: MMAR_1753(purU)
CGL: NCgl0371(purU)
CGB: cg0457(purU)
CGT: cgR_0456(purU)
CEF: CE0400(purU)
NFA: nfa52050(purU)
RHA: RHA1_ro01818 RHA1_ro02096(purU)
RER: RER_15920(purU)
ROP: ROP_14950(purU) ROP_17670(purU)
GBR: Gbro_0786
SCO: SCO4403(purU)
SMA: SAV_3846(purU)
SGR: SGR_3063(purU)
LXX: Lxx19400(purU)
CMI: CMM_2532(purU)
CMS: CMS_0596
ART: Arth_1114 Arth_3699 Arth_3717
AAU: AAur_0485(purU) AAur_1226(purU) AAur_3831(purU)
ACH: Achl_1188 Achl_3462 Achl_3590
RSA: RSal33209_0268
KRH: KRH_18160(purU) KRH_21480(purU)
MLU: Mlut_04640
BCV: Bcav_2993
BFA: Bfae_15420
JDE: Jden_0690
XCE: Xcel_0748
PAC: PPA1739
NCA: Noca_0127 Noca_0643
TFU: Tfu_2356
TCU: Tcur_3853
SRO: Sros_7341
FAL: FRAAL2311(purU)
ACE: Acel_0154
NML: Namu_3621 Namu_4965
KRA: Krad_3983
SEN: SACE_4502(purU-2) SACE_6982(purU)
SVI: Svir_02600 Svir_11670 Svir_18880
AMI: Amir_6765
CAI: Caci_8736
SUS: Acid_0156
BTH: BT_1381
BVU: BVU_3850
CHU: CHU_3078(purU)
DFE: Dfer_3669
CPI: Cpin_2012
PHE: Phep_3999
GFO: GFO_0482(purU)
FJO: Fjoh_2326
RBI: RB2501_11097
FSU: Fisuc_0464
OTE: Oter_0678
RBA: RB256(purU)
SYN: sll0070(purU)
SYW: SYNW2504(purU)
SYC: syc0537_d(purU)
SYF: Synpcc7942_1008(purU)
SYD: Syncc9605_2671
SYE: Syncc9902_2300
SYG: sync_2917(purU)
SYR: SynRCC307_2512(purU)
SYX: SynWH7803_2509(purU)
SYP: SYNPCC7002_A1006(purU)
CYA: CYA_0760(purU)
CYB: CYB_2447(purU)
TEL: tll0183(purU)
MAR: MAE_53010(purU)
CYT: cce_0404(purU)
CYP: PCC8801_4374(purU)
CYC: PCC7424_0012(purU)
CYN: Cyan7425_4033
CYH: Cyan8802_4436
GVI: gll4325
ANA: alr1623(purU)
NPU: Npun_F0555(purU)
AVA: Ava_4234(purU)
PMM: PMM1702(purU)
PMT: PMT2253(purU)
PMN: PMN2A_1311
PMI: PMT9312_1795(purU)
PMB: A9601_19121(purU)
PMC: P9515_18931(purU)
PMF: P9303_30021(purU)
PMG: P9301_18931(purU)
PMH: P9215_19751(purU)
PMJ: P9211_18381
PME: NATL1_21841(purU)
AMR: AM1_4512(purU)
CTE: CT1825(purU)
CPC: Cpar_1675(purU)
CPH: Cpha266_0692(purU)
CPB: Cphamn1_1789(purU)
CLI: Clim_0638(purU)
PVI: Cvib_0515(purU)
PLT: Plut_0467(purU)
PPH: Ppha_2199(purU)
PAA: Paes_1668(purU)
DET: DET1237(purU)
DEH: cbdb_A1158(purU)
DEB: DehaBAV1_1052
DEV: DhcVS_1023
DRA: DR_0584(purU)
DGE: Dgeo_1488(purU)
DDR: Deide_09620
TTH: TTC0957(purU)
TTJ: TTHA1321(purU)
AAE: aq_1818(purU)
TTR: Tter_0375
HAL: VNG1946G(purU)
HSL: OE3735F(purU)
HMA: rrnAC3272(purU)
HWA: HQ3129A(purU)
NPH: NP5006A(purU)
HLA: Hlac_1251
HUT: Huta_2219
HMU: Hmuk_1421
NMR: Nmar_0223
Taxonomy
Reference
  Authors
  Title
  Journal
 1
Huennekens, F.M.
Enzymatic deacylation of N10-formyltetrahydrofolic acid.
Fed. Proc. 16 (1957) 199.
Other DBs ExplorEnz - The Enzyme Database: 3.5.1.10
IUBMB Enzyme Nomenclature: 3.5.1.10
ExPASy - ENZYME nomenclature database: 3.5.1.10
BRENDA, the Enzyme Database: 3.5.1.10
CAS: 9025-08-5
DBGET integrated database retrieval system