| Entry |
|
|---|
| Name |
biotinidase;
amidohydrolase biotinidase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
 |
|---|
| Sysname |
biotin-amide amidohydrolase |
|---|
| Reaction(IUBMB) |
biotin amide + H2O = biotin + NH3 [RN:R01076] |
|---|
| Reaction(KEGG) |
R01076;
(other) R01077 R06134
 |
|---|
| Substrate |
biotin amide [CPD:C01893];
H2O [CPD:C00001] |
|---|
| Product |
biotin [CPD:C00120];
NH3 [CPD:C00014] |
|---|
| Comment |
Also acts on biotin esters. |
|---|
| Pathway |
PATH: ec00780 Biotin metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K01435 biotinidase |
|---|
| Genes |
HSA: 686(BTD)
MCC: 677722(BTD)
MMU: 26363(Btd)
RNO: 306262(Btd)
CFA: 477059(BTD)
BTA: 537669(BTD)
SSC: 100155150
ECB: 100063800(BTD)
MDO: 100030538
OAA: 100084040
GGA: 420639(BTD)
TGU: 100226458
DRE: 555376
DME: Dmel_CG32754(vanin-like)
DPO: Dpse_GA17117
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14087327]
KNAPPE J, BRUEMMER W, BIEDERBICK K.
[PURIFICATION AND PROPERTIES OF BIOTINIDASE FROM SWINE KIDNEY AND
LACTOBACILLUS CASEI.]
Biochem. Z. 338 (1963) 599-613.
Lactobacillus casei |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13211594]
THOMA RW, PETERSON WH.
The enzymatic degradation of soluble bound biotin.
J. Biol. Chem. 210 (1954) 569-79.
Sus scofa [GN:ssc] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.1.12
IUBMB Enzyme Nomenclature: 3.5.1.12
ExPASy - ENZYME nomenclature database: 3.5.1.12
BRENDA, the Enzyme Database: 3.5.1.12
CAS: 9025-15-4 |
|---|
