| Entry |
|
|---|
| Name |
nicotinamidase;
nicotinamide deaminase;
nicotinamide amidase;
YNDase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
 |
|---|
| Sysname |
nicotinamide amidohydrolase |
|---|
| Reaction(IUBMB) |
nicotinamide + H2O = nicotinate + NH3 [RN:R01268] |
|---|
| Reaction(KEGG) |
R01268;
(other) R06134
 |
|---|
| Substrate |
nicotinamide [CPD:C00153];
H2O [CPD:C00001] |
|---|
| Product |
nicotinate [CPD:C00253];
NH3 [CPD:C00014] |
|---|
| Pathway |
PATH: ec00760 Nicotinate and nicotinamide metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K01440 nicotinamidase |
|---|
| Genes |
SPU: 759419
SCE: YGL037C(PNC1)
AGO: AGOS_AFR466C
KLA: KLLA0F22242g
PIC: PICST_33075(PNC1)
VPO: Kpol_1041p36
LEL: LELG_05168
CGR: CAGL0A01716g
YLI: YALI0A21153g
FGR: FG09196.1
AFV: AFLA_087380
CNE: CNA07780
LBC: LACBIDRAFT_181719
MGL: MGL_1568
ECO: b1768(pncA)
ECJ: JW1757(pncA)
ECD: ECDH10B_1906(pncA)
EBW: BWG_1581(pncA)
ECE: Z2802(ydjB)
ECS: ECs2475
ECF: ECH74115_2489(pncA)
ETW: ECSP_2337(pncA)
ECG: E2348C_1895(pncA)
ECC: c2172(ydjB)
ECI: UTI89_C1964(ydjB)
ECP: ECP_1716
ECV: APECO1_837(ydjB)
ECW: EcE24377A_1992(pncA)
ECX: EcHS_A1852(pncA)
ECM: EcSMS35_1423(pncA)
ECY: ECSE_1939
ECL: EcolC_1864
ECK: EC55989_1937(pncA)
ECQ: ECED1_1970(pncA)
ECR: ECIAI1_1831(pncA)
ECT: ECIAI39_1287(pncA)
ECZ: ECS88_1820(pncA)
EUM: ECUMN_2057(pncA)
ELF: LF82_1676(pncA)
EBL: B21_01725(pncA)
EBD: ECBD_1876
EBR: ECB_01737(pncA)
EOH: ECO103_1962(pncA)
EOI: ECO111_2279(pncA)
EOJ: ECO26_2543(pncA)
EFE: EFER_1296(pncA)
STY: STY1821(pncA)
STT: t1172(pncA)
SPT: SPA1551(pncA)
SEK: SSPA1442
SPQ: SPAB_02051
SEI: SPC_2439(pncA)
SEC: SC1315(pncA)
SEH: SeHA_C1420
SEE: SNSL254_A1404
SEW: SeSA_A1387
SEA: SeAg_B1882
SED: SeD_A2053
SEG: SG1823(pncA)
SET: SEN1750(pncA)
SES: SARI_01686
STM: STM1293(pncA)
YPE: YPO2160(pncA)
YPK: y2162
YPM: YP_1960(pncA)
YPA: YPA_1517
YPN: YPN_1626
YPG: YpAngola_A2348(pncA)
YPP: YPDSF_0974
YPS: YPTB2086(pncA)
YPI: YpsIP31758_1984(pncA)
YPY: YPK_2093
YPB: YPTS_2149
YEN: YE2262(nam)
SFL: SF1455(ydjB)
SFX: S1570(ydjB)
SFV: SFV_1449(ydjB)
SSN: SSON_1387(ydjB)
SBO: SBO_1319(ydjB)
SBC: SbBS512_E2023(pncA)
SDY: SDY_1505(ydjB)
ECA: ECA2341(pncA)
PCT: PC1_1968
PWA: Pecwa_2264
ETA: ETA_15630(pncA)
PLU: plu2555(pncA)
PAY: PAU_01977(ydjB)
ENT: Ent638_1679
ESA: ESA_02167
CTU: Ctu_18060(pncA)
KPN: KPN_01202(pncA)
KPE: KPK_3242(pncA)
KPU: KP1_2228(pncA)
CKO: CKO_01797
SPE: Spro_2724
PMR: PMI1501(pncA)
EIC: NT01EI_1644
ETR: ETAE_1486(pncA)
DDA: Dd703_1970
DDC: Dd586_2159
DZE: Dd1591_2212
XFT: PD1310(pncA)
XFM: Xfasm12_1467
XFN: XfasM23_1394
SML: Smlt0257(pncA)
SMT: Smal_0214
VCH: VCA0712
VCO: VC0395_0651(pncA)
VCM: VCM66_A0670(pncA)
VCJ: VCD_000607
VVU: VV1_2374
VVY: VV1967
VPA: VPA0307
PPR: PBPRA3449
PAE: PA4918
PAU: PA14_64950(pncA)
PST: PSPTO_3295(pncA)
PSB: Psyr_3125
PSP: PSPPH_3038(pncA)
PFL: PFL_2466(pncA)
PFO: Pfl01_2887
PEN: PSEEN2059
PMY: Pmen_1412
AVN: Avin_46220(pncA)
ACI: ACIAD3584(pncA)
ACB: A1S_3422
ABM: ABSDF3605(pncA)
ABY: ABAYE0059(pncA)
ABC: ACICU_03618
ABN: AB57_3875
ABB: ABBFA_000061
ILO: IL0104
PIN: Ping_1729
CBS: COXBURSA331_A0906
CBD: CBUD_1010
CBG: CbuG_0974
CBC: CbuK_0806
LPN: lpg0271(pncA)
LPF: lpl0323(pncA)
LPP: lpp0345(pncA)
LPC: LPC_0347(pncA)
MCA: MCA2761
FTH: FTH_0920
NOC: Noc_0271
AEH: Mlg_1258
HHA: Hhal_1744
TGR: Tgr7_0123
CSA: Csal_2870
AHA: AHA_4211
ASA: ASA_0114(pncA)
NMA: NMA0244
NME: NMB2157
NMC: NMC2135(pncA)
NGO: NGO1933
CVI: CV_1264(pncA)
RSO: RSc1760(pncA)
RPI: Rpic_1446
RPF: Rpic12D_1487
REU: Reut_A1406
REH: H16_A1527(pncA)
RME: Rmet_1854
CTI: RALTA_A1468(pncA)
BMA: BMA1437(pncA)
BMV: BMASAVP1_A1927(pncA)
BML: BMA10229_A3377(pncA)
BMN: BMA10247_1200(pncA)
BPS: BPSL1425
BPM: BURPS1710b_2454(pncA)
BPL: BURPS1106A_2332(pncA)
BPD: BURPS668_2293(pncA)
BPR: GBP346_A2402
BTE: BTH_I2143
BVI: Bcep1808_1837
BUR: Bcep18194_A5206
BCN: Bcen_6174
BCH: Bcen2424_1905
BCM: Bcenmc03_1928
BCJ: BCAL1978
BAM: Bamb_1893
BAC: BamMC406_1823
BMU: Bmul_1369
BMJ: BMULJ_01874(pncA)
BPH: Bphy_1029
BGL: bglu_1g13720
BPE: BP3506
BPA: BPP2513
BBR: BB1959
RFR: Rfer_0828
VEI: Veis_0861
VAP: Vapar_0187
NMU: Nmul_A0906
GSU: GSU2290
GME: Gmet_2374
GUR: Gura_1739
GBM: Gbem_1963
GEO: Geob_3433
GEM: GM21_2254
PCA: Pcar_1461
DMA: DMR_20590(pncA)
DAT: HRM2_31960(pncA)
ADE: Adeh_1318
ACP: A2cp1_2638
AFW: Anae109_2445
ANK: AnaeK_2542
SCL: sce3711
SAT: SYN_01201
MLO: mlr4882
MES: Meso_3207
SME: SMc02275(pncA)
SMD: Smed_0199
ATU: Atu2066(pncA)
ATC: AGR_C_3739
ARA: Arad_2959(pncA)
AVI: Avi_2845(pncA)
RET: RHE_CH02821(pncA)
REC: RHECIAT_CH0002971(pncA)
RLE: RL3279(pncA)
RLT: Rleg2_2566
RLG: Rleg_2825
RHI: NGR_c02110
BME: BMEI0546
BMF: BAB1_1484
BMB: BruAb1_1459(pncA)
BMC: BAbS19_I13870
BMS: BR1464(pncA)
BMT: BSUIS_A1517
BOV: BOV_1420(pncA)
BCS: BCAN_A1499
BMR: BMI_I1476(pncA)
OAN: Oant_1709
BJA: bll0677(pncA) bll4549(pncA)
BRA: BRADO2106(pncA)
BBT: BBta_0189 BBta_2415(pncA)
BHE: BH11400(pncA)
BQU: BQ09020(pncA)
BBK: BARBAKC583_0960
BTR: Btr_1607(pncA)
BGR: Bgr_14140(pncA)
XAU: Xaut_0349
AZC: AZC_4282
MEX: Mext_3904
MEA: Mex_1p4281(pncA)
MDI: METDI4892(pncA)
MRD: Mrad2831_1643
MET: M446_3227
MPO: Mpop_4376
MCH: Mchl_4273
MNO: Mnod_5120
BID: Bind_1593
PZU: PHZ_c0647
SIL: SPO0093(pncA)
SIT: TM1040_3430
RSP: RSP_1368(pncA)
RSH: Rsph17029_0036
RSQ: Rsph17025_0026
RSK: RSKD131_2767
JAN: Jann_0014
RDE: RD1_0585(pncA)
PDE: Pden_0851
DSH: Dshi_3347(pncA)
ACR: Acry_0085
GDI: GDI_3208(pncA)
GDJ: Gdia_3153
APT: APA01_19190
RRU: Rru_A3002
RCE: RC1_1683(pncA)
MGM: Mmc1_1211
BCZ: BCZK0017(pncA) BCZK2041(pncA)
BTK: BT9727_2043(pncA)
BTL: BALH_0017(pncA)
BCL: ABC3111
GTN: GTNG_1706
SAB: SAB1855
LMO: lmo2571
LMF: LMOf2365_2544
LIN: lin2716
LWE: lwe2522
SPZ: M5005_Spy_1511
SPH: MGAS10270_Spy1579
SPI: MGAS10750_Spy1571
SPJ: MGAS2096_Spy1538
SPK: MGAS9429_Spy1512
SPF: SpyM50334
SPA: M6_Spy1504
SPB: M28_Spy1500
SPN: SP_1583
SPD: SPD_1411
SPR: spr1438(entB)
SPW: SPCG_1566(entB)
STC: str1634(entB)
STL: stu1634(entB)
STE: STER_1598
SSA: SSA_0567
SSV: SSU98_0342
LPL: lp_2612
LSA: LSA1766
LSL: LSL_1510(pncA)
LDB: Ldb0322(pncA)
LBR: LVIS_0241
LCA: LSEI_2767
CTC: CTC00699
CBO: CBO1134(nam)
CBA: CLB_1171
CBH: CLC_1183
CBY: CLM_1290
CBL: CLK_0574
CBB: CLD_3429
CBI: CLJ_B1181
CBF: CLI_1220
CPO: COPRO5265_0388(pncA)
MMY: MSC_1020(pncA) MSC_1045(pncA)
MCP: MCAP_0859(pncA)
MFL: Mfl340
MTU: Rv2043c(pncA)
MTC: MT2103(pncA)
MRA: MRA_2058(pncA)
MTF: TBFG_12080
MTB: TBMG_01938(TBMG_01938.1)
MBO: Mb2069c(pncA)
MBB: BCG_2062c(pncA)
MBT: JTY_2057(pncA)
MPA: MAP1774c(pncA)
MAV: MAV_2472
MSM: MSMEG_6506
MVA: Mvan_5728
MGI: Mflv_1089
MAB: MAB_1472c
MMC: Mmcs_5114
MMI: MMAR_3016(pncA)
CGL: NCgl2401(cgl2487)
CGB: cg2734(pncA)
CGT: cgR_2400
CEF: CE2385
CJK: jk1464(pncA)
CUR: cur_0605
CAR: cauri_1709(pncA)
CKP: ckrop_0570
NFA: nfa10840(pncA)
RER: RER_38860(pncA)
ROP: ROP_11520(pncA)
GBR: Gbro_1958
SCO: SCO2918(SCE19A.18)
SMA: SAV_5157(pncA)
SGR: SGR_4621
TWH: TWT692(pncA)
TWS: TW711(pncA)
CMI: CMM_0932(pncA)
CMS: CMS_0192
ART: Arth_2587
AAU: AAur_2576
ACH: Achl_2319
RSA: RSal33209_1467
KRH: KRH_09960(pncA)
MLU: Mlut_08310
BCV: Bcav_0958
BFA: Bfae_06120
JDE: Jden_1959
KSE: Ksed_10680
XCE: Xcel_2734
PAC: PPA0993
TFU: Tfu_2374
TCU: Tcur_3877
SRO: Sros_1721
FRE: Franean1_5162
FAL: FRAAL2123(pncA)
ACE: Acel_1717
NML: Namu_1692
KRA: Krad_3768
SEN: SACE_1199(pncA) SACE_2641(pncA)
SVI: Svir_29250
AMI: Amir_1003
STP: Strop_1096
SAQ: Sare_0985
CAI: Caci_1488
BLO: BL0897(pncA)
BLJ: BLD_0635(pncA)
BLN: Blon_1622
CCU: Ccur_08090
BBZ: BbuZS7_E15(pncA)
BDU: BDU_1138(pncA)
BRE: BRE_1105(pncA)
TPA: TP0696
BHY: BHWA1_00211(pncA)
ACA: ACP_3137
PGI: PG0678
PGN: PGN_0714
SRU: SRU_1457(pncA)
RMR: Rmar_0822
GFO: GFO_3188(pncA)
FBA: FIC_01416
COC: Coch_2050
STR: Sterm_2621
OTE: Oter_1042
TAI: Taci_1444
DDR: Deide_16480
AAE: aq_994(pncA)
SUL: SYO3AOP1_0602
SAF: SULAZ_0696
PMX: PERMA_0323
PMO: Pmob_1540
HWA: HQ1060A(entB)
NPH: NP1274A(entB_1)
PHO: PH0999
PAB: PAB1720
PFU: PF1105
TKO: TK1650
TON: TON_1968
TGA: TGAM_1135(pncA)
TSI: TSIB_1670
KCR: Kcr_0818
 |
|---|
| Structures |
PDB: 1ILW 1IM5 2H0R 2WT9 2WTA |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14285515]
PETRACK B, GREENGARD P, CRASTON A, SHEPPY F.
NICOTINAMIDE DEAMIDASE FROM MAMMALIAN LIVER.
J. Biol. Chem. 240 (1965) 1725-30.
Rattus norvegicus [GN:rno], Oryctolagus cuniculus, pigeon |
|---|
Reference
Authors
Title
Journal
|
2
Sarma, D.S.R., Rajalakshmi, S. and Sarma, S.
Studies on the enzymes involved in nicotinamide adenine dinucleotide
metabolism in Aspergillus niger.
Biochim. Biophys. Acta 81 (1964) 311-322. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.1.19
IUBMB Enzyme Nomenclature: 3.5.1.19
ExPASy - ENZYME nomenclature database: 3.5.1.19
BRENDA, the Enzyme Database: 3.5.1.19
CAS: 9033-32-3 |
|---|
