| Entry |
|
|---|
| Name |
omega-amidase;
alpha-keto acid-omega-amidase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
 |
|---|
| Sysname |
omega-amidodicarboxylate amidohydrolase |
|---|
| Reaction(IUBMB) |
a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3
[RN:R03804] |
|---|
| Reaction(KEGG) |
R03804 > R00269 R00348;
(other) R06134
 |
|---|
| Substrate |
monoamide of a dicarboxylic acid [CPD:C04131];
H2O [CPD:C00001] |
|---|
| Product |
dicarboxylate [CPD:C02028];
NH3 [CPD:C00014] |
|---|
| Comment |
Acts on glutaramate, succinamate and their 2-oxo derivatives. |
|---|
| Pathway |
PATH: ec00250 Alanine, aspartate and glutamate metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14392177]
MEISTER A, LEVINTOW L, GREENFIELD RE, ABENDSCHEIN PA.
Hydrolysis and transfer reactions catalyzed by omega-amidase
preparations.
J. Biol. Chem. 215 (1955) 441-60.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13502341]
MEISTER A, RADHAKRISHNAN AN, BUCKLEY SD.
Enzymatic synthesis of L-pipecolic acid and L-proline.
J. Biol. Chem. 229 (1957) 789-800.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.1.3
IUBMB Enzyme Nomenclature: 3.5.1.3
ExPASy - ENZYME nomenclature database: 3.5.1.3
BRENDA, the Enzyme Database: 3.5.1.3
CAS: 9025-19-8 |
|---|
