KEGG   ENZYME: 3.5.1.32Help
Entry
EC 3.5.1.32                 Enzyme                                 
Name hippurate hydrolase
Class Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname N-benzoylamino-acid amidohydrolase
Reaction(IUBMB) hippurate + H2O = benzoate + glycine [RN:R01424]
Reaction(KEGG) R01424
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Substrate hippurate [CPD:C01586];
H2O [CPD:C00001]
Product benzoate [CPD:C00180];
glycine [CPD:C00037]
Comment Acts on various N-benzoylamino acids.
Pathway PATH: ec00360  Phenylalanine metabolism
PATH: ec01064  Biosynthesis of alkaloids derived from ornithine,
               lysine and nicotinic acid
Orthology KO: K01451  hippurate hydrolase
Genes TET: TTHERM_00379080
ECE: Z5522
ECS: ECs4892
ECF: ECH74115_5424
ETW: ECSP_5032
ECG: E2348C_4277
ECC: c4924
ECI: UTI89_C4556
ECP: ECP_4178
ECV: APECO1_2502
ECQ: ECED1_4670
ECZ: ECS88_4420
ELF: LF82_p628
EFE: EFER_3799
SDY: SDY_3770
ECA: ECA1004
ETA: ETA_22260
SGL: SG1744
KPN: KPN_00523 KPN_00966 KPN_01294 KPN_02091
KPE: KPK_2239 KPK_3118 KPK_4060
KPU: KP1_1448 KP1_1936 KP1_2339 KP1_3179
SPE: Spro_3206
DDA: Dd703_1216 Dd703_1812 Dd703_3456
DDC: Dd586_1289 Dd586_1862 Dd586_2912
DZE: Dd1591_2808
XCV: XCV0161
SML: Smlt2104
SMT: Smal_1698
VHA: VIBHAR_04931
VSP: VS_II0051
PAE: PA2922 PA4344
PAU: PA14_26260 PA14_56480
PAP: PSPA7_4914
PAG: PLES_21421 PLES_47221
PPU: PP_2704
PPF: Pput_2611
PPG: PputGB1_2753 PputGB1_3083
PPW: PputW619_2549 PputW619_2995
PST: PSPTO_1882
PSB: Psyr_3523
PSP: PSPPH_3465
PFL: PFL_1344 PFL_3535
PFO: Pfl01_1291
ACB: A1S_0731
ABY: ABAYE3086
ABC: ACICU_00672 ACICU_02831
ABN: AB57_0776 AB57_2996
ABB: ABBFA_000891 ABBFA_002886
SDN: Sden_3487
SFR: Sfri_3605
SLO: Shew_2688
SPL: Spea_2928 Spea_4074
SHL: Shal_0171 Shal_3019
SWD: Swoo_0112 Swoo_3374
SWP: swp_3566
CPS: CPS_0854 CPS_4917
PHA: PSHAa2344
PAT: Patl_2787
SDE: Sde_1645
PIN: Ping_2027
TTU: TERTU_4007
CBU: CBU_0362
CBS: COXBURSA331_A0469
CBD: CBUD_1720
CBG: CbuG_1646
CBC: CbuK_0554
FTL: FTL_0753
TCX: Tcr_0219
HNA: Hneap_2199
CSA: Csal_1708
MMW: Mmwyl1_2454
CVI: CV_1884(hipO) CV_2102
RSO: RSc2871(hipO)
RPI: Rpic_1410 Rpic_2524 Rpic_2778 Rpic_3113
RPF: Rpic12D_1452 Rpic12D_2374 Rpic12D_2748
REU: Reut_A0051 Reut_A3007 Reut_A3289 Reut_B4300 Reut_B5217
     Reut_B5812
REH: H16_A0073 H16_A3299(hipO) H16_B0605 H16_B1473 H16_B1753
RME: Rmet_0021 Rmet_3159 Rmet_4507 Rmet_5222
CTI: RALTA_A0032 RALTA_A2755 RALTA_B1534 RALTA_B1819(hipO)
     RALTA_B1875
BMA: BMAA1494(hipO-1) BMAA1941(hipO-2)
BMV: BMASAVP1_0958(hipO-2)
BML: BMA10229_1245(hipO-2) BMA10229_2111(hipO-1)
BMN: BMA10247_A0794(hipO-1) BMA10247_A2220(hipO-2)
BPS: BPSS0148 BPSS0271
BPM: BURPS1710b_A1662(hipO-2) BURPS1710b_A1808(hipO-1)
BPL: BURPS1106A_A0205 BURPS1106A_A0378
BPD: BURPS668_A0295 BURPS668_A0476
BTE: BTH_II0217
BVI: Bcep1808_1595 Bcep1808_3597 Bcep1808_5855 Bcep1808_6408
     Bcep1808_6694
BUR: Bcep18194_A4387 Bcep18194_A4797 Bcep18194_B0058 Bcep18194_B0252
     Bcep18194_B0948 Bcep18194_B1298 Bcep18194_B2598 Bcep18194_C7452
BCN: Bcen_1169 Bcen_2992 Bcen_3600 Bcen_3715 Bcen_3821 Bcen_5231
     Bcen_6435
BCH: Bcen2424_1649 Bcen2424_4547 Bcen2424_4653 Bcen2424_4767
     Bcen2424_5374 Bcen2424_5628 Bcen2424_6670
BCM: Bcenmc03_1624 Bcenmc03_4601 Bcenmc03_4896 Bcenmc03_5516
     Bcenmc03_5651 Bcenmc03_5757 Bcenmc03_6268
BCJ: BCAL1703 BCAM1729 BCAM2574 BCAM2785 BCAS0397
BAM: Bamb_1550 Bamb_3971 Bamb_4721 Bamb_4907 Bamb_5843 Bamb_5896
     Bamb_6319 Bamb_6364
BAC: BamMC406_1569 BamMC406_4433 BamMC406_5250 BamMC406_5455
     BamMC406_5626 BamMC406_6019 BamMC406_6067
BMU: Bmul_1589 Bmul_3358 Bmul_3967 Bmul_4102 Bmul_5140
BMJ: BMULJ_01654(hipO) BMULJ_03377(hipO) BMULJ_04402(hipO)
     BMULJ_04535(hipO) BMULJ_05168(hipO)
BXE: Bxe_A0472 Bxe_A2955 Bxe_B0069 Bxe_B2175
BPH: Bphy_1825 Bphy_2687 Bphy_3769
BPY: Bphyt_1519 Bphyt_3484 Bphyt_5519 Bphyt_5935
BGL: bglu_2g10460 bglu_2g18940 bglu_2g20890
PNU: Pnuc_0152
BPE: BP2810 BP3036
BPA: BPP3730 BPP3763
BBR: BB4176 BB4209
BPT: Bpet0686 Bpet0715
BAV: BAV0964 BAV2859 BAV2890 BAV3124
RFR: Rfer_3615
POL: Bpro_0044 Bpro_0749 Bpro_2111 Bpro_2533 Bpro_4523
PNA: Pnap_0651 Pnap_1248
AAV: Aave_0770 Aave_0935 Aave_2179 Aave_3677
AJS: Ajs_0453 Ajs_0687
VEI: Veis_1301 Veis_4256 Veis_4728 Veis_4882
DAC: Daci_1132 Daci_2476 Daci_4012 Daci_5133 Daci_5679
DIA: Dtpsy_0444 Dtpsy_0665
VAP: Vapar_0333 Vapar_1090
CTT: CtCNB1_0168 CtCNB1_2261 CtCNB1_3324 CtCNB1_3360 CtCNB1_4279
     CtCNB1_4300 CtCNB1_4350
MPT: Mpe_A3092
HAR: HEAR0220
MMS: mma_0273(hipO1) mma_3336(hipO2)
LCH: Lcho_2379 Lcho_3382
NMU: Nmul_A0853
EBA: ebA5427
AZO: azo0205(hipO1) azo1605(hipO2)
DAR: Daro_0071
TMZ: Tmz1t_0143 Tmz1t_1302
APP: CAP2UW1_0400
CJE: Cj0985c(hipO)
CJR: CJE1067(hipO)
CJJ: CJJ81176_1004(hipO)
CJU: C8J_0924(hipO)
CJD: JJD26997_0803(hipO)
GME: Gmet_3443
GBM: Gbem_2148 Gbem_2228
GEM: GM21_1999
DDE: Dde_3033
DSA: Desal_1947 Desal_2583
DBA: Dbac_0877
ADE: Adeh_3172
ACP: A2cp1_3364
MXA: MXAN_5097
SCL: sce2384
SAT: SYN_00083
MLO: mlr3583 mlr7940
MES: Meso_2532 Meso_3056
SME: SM_b21279 SMc00682(hipO1) SMc02256(hipO2)
SMD: Smed_0172 Smed_2573 Smed_4612
ATU: Atu2732(hipO) Atu3419 Atu3445 Atu3635 Atu4428 Atu4444
ATC: AGR_C_4953 AGR_L_2386 AGR_L_2766 AGR_L_2806 AGR_L_849 AGR_L_879
ARA: Arad_0263 Arad_4246(hipO) Arad_7670 Arad_8823 Arad_9070
     Arad_9349(hipO) Arad_9685(hipO)
AVI: Avi_3872 Avi_4062 Avi_4372(hipO) Avi_5199 Avi_7215
RET: RHE_CH03429(ypch01210) RHE_CH03833(hipO) RHE_PC00005(ypc00003)
REC: RHECIAT_CH0002235 RHECIAT_CH0003665(hipO) RHECIAT_CH0004104
RLE: RL3888(hipO) RL4364 pRL100225
RLT: Rleg2_0628 Rleg2_3165 Rleg2_3609 Rleg2_5073 Rleg2_5220
     Rleg2_5562
RLG: Rleg_3456 Rleg_3897 Rleg_4779 Rleg_5405
RHI: NGR_c01920 NGR_c18520 NGR_c27330
BMF: BAB1_2038
BMB: BruAb1_2012
BMC: BAbS19_I19090
BMS: BR2037
BOV: BOV_1959
BCS: BCAN_A2083
OAN: Oant_0901 Oant_3314 Oant_4353
BJA: blr3021 blr5602 blr5691
BRA: BRADO1957 BRADO2642 BRADO2819 BRADO2917
BBT: BBta_2260 BBta_2982 BBta_5260 BBta_5364
RPA: RPA2647 RPA3439 RPA3729
RPB: RPB_1734 RPB_2126 RPB_3086
RPC: RPC_1193 RPC_1729
RPD: RPD_3295 RPD_3565
RPE: RPE_1821
RPT: Rpal_2919 Rpal_3928 Rpal_4250
NWI: Nwi_2262
NHA: Nham_2671 Nham_3968
OCA: OCAR_6660
XAU: Xaut_4367
AZC: AZC_1987 AZC_2075 AZC_2197
MEX: Mext_2692 Mext_4317
MEA: Mex_1p2885 Mex_1p4714
MDI: METDI3451 METDI4468 METDI5320
MRD: Mrad2831_2323 Mrad2831_3584 Mrad2831_4829
MET: M446_3187 M446_4664
MPO: Mpop_2815 Mpop_4834
MCH: Mchl_2919 Mchl_4686
MNO: Mnod_0245 Mnod_2925
CCR: CC_2809
CCS: CCNA_02900
SIL: SPO1214 SPO2195 SPO2468 SPO2808 SPO2809 SPO2810 SPO2811
SIT: TM1040_0512 TM1040_0718 TM1040_0719 TM1040_0937
RSP: RSP_2910
RSH: Rsph17029_1555
RSQ: Rsph17025_1110
RSK: RSKD131_1228
JAN: Jann_2343 Jann_3241 Jann_3289 Jann_4150
RDE: RD1_3132 RD1_3310
PDE: Pden_0186 Pden_0610 Pden_1199
DSH: Dshi_1161 Dshi_1288
MMR: Mmar10_1822
HNE: HNE_0694
HBA: Hbal_2568
NAR: Saro_2348 Saro_2932
SAL: Sala_0940 Sala_2314
SWI: Swit_3041 Swit_3434
ELI: ELI_05285
GBE: GbCGDNIH1_0963
ACR: Acry_1211 Acry_1887 Acry_2229 Acry_3534
RRU: Rru_A0984 Rru_A1813 Rru_A2871
RCE: RC1_1002
SAJ: SaurJH9_0090
SUB: SUB0909
AMT: Amet_1622
ATE: Athe_1911
CSC: Csac_1034
NTH: Nther_0613
MPE: MYPE3540
MPA: MAP2718c
MAV: MAV_3492
MSM: MSMEG_3989
MVA: Mvan_4743
MGI: Mflv_1971
MAB: MAB_4738c
MMC: Mmcs_1337
MKM: Mkms_1355
MJL: Mjls_1373
CGL: NCgl2003(cgl2083)
CGB: cg2285(hipO)
CGT: cgR_1968 cgR_2829
CEF: CE1986 CE2595
CDI: DIP1551
CJK: jk0802(amiB)
CUR: cur_1160 cur_1464
CAR: cauri_0948 cauri_1610(amiB) cauri_1838
CKP: ckrop_0800
RHA: RHA1_ro02502
RER: RER_12360 RER_58000
ROP: ROP_22290 ROP_26330
GBR: Gbro_0648
SCO: SCO4103(SCD17.07c)
SGR: SGR_4419
ART: Arth_3776
AAU: AAur_0981 AAur_3553
ACH: Achl_3433 Achl_3669
RSA: RSal33209_0888
KRH: KRH_06990
MLU: Mlut_02420
BCV: Bcav_0543
BFA: Bfae_19910
JDE: Jden_0023
KSE: Ksed_23130
NCA: Noca_3715
TFU: Tfu_2437 Tfu_2564
SRO: Sros_7680
FAL: FRAAL4820
SEN: SACE_2685
SVI: Svir_36900
AMI: Amir_0169 Amir_2847
STP: Strop_2416
SAQ: Sare_2568
CAI: Caci_1139 Caci_3698 Caci_7975
RXY: Rxyl_0180
AFO: Afer_1992
SHI: Shel_28190
ELE: Elen_0991
ABA: Acid345_1597 Acid345_2056
RMR: Rmar_0545
CPI: Cpin_7287
FBA: FIC_01065
AAS: Aasi_1096
GAU: GAU_2023
TAI: Taci_1675
AVA: Ava_4094
CPC: Cpar_0982
CCH: Cag_0903
CPB: Cphamn1_1324
CLI: Clim_1254
PVI: Cvib_0893
PLT: Plut_1020
PPH: Ppha_1361
PAA: Paes_1044
CTS: Ctha_1691
RRS: RoseRS_1741
RCA: Rcas_2022
CAU: Caur_1560
CAG: Cagg_2224
CHL: Chy400_1695
TRO: trd_A0657
MPL: Mpal_2730
Taxonomy
Reference
  Authors
  Title



  Journal
 1
Rohr, M.
Hippurathydrolase, ein neues Enzym aus Mikroorganismen. I Mitt.
Induzierte Biosynthese in Fusarium semitectum. Darstellung einer
gereinigten Enzympraparation und Untersuchungen zur
Substratspezifitat.
Monatchefte Chem. 99 (1968) 2255-2277.
Reference
  Authors
  Title

  Journal
 2
Rohr, M.
Hippurathydrolase, ein neues Enzym aus Mikroorganismen. II Mitt.
Enzymeigenschaften.
Monatchefte Chem. 99 (1968) 2278-2290.
Reference
  Authors
  Title

  Journal
 3  [PMID:3922754]
Rohrmann K, Niemann R, Buddecke E.
Two N-acetylgalactosaminyltransferase are involved in the
biosynthesis of chondroitin sulfate.
Eur. J. Biochem. 148 (1985) 463-9.
Other DBs ExplorEnz - The Enzyme Database: 3.5.1.32
IUBMB Enzyme Nomenclature: 3.5.1.32
ExPASy - ENZYME nomenclature database: 3.5.1.32
BRENDA, the Enzyme Database: 3.5.1.32
CAS: 37278-43-6
DBGET integrated database retrieval system