KEGG   ENZYME: 3.5.1.49Help
Entry
EC 3.5.1.49                 Enzyme                                 
Name formamidase
Class Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname formamide amidohydrolase
Reaction(IUBMB) formamide + H2O = formate + NH3 [RN:R00524]
Reaction(KEGG) R00524
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Substrate formamide [CPD:C00488];
H2O [CPD:C00001]
Product formate [CPD:C00058];
NH3 [CPD:C00014]
Comment Also acts, more slowly, on acetamide, propanamide and butanamide.
Pathway PATH: ec00630  Glyoxylate and dicarboxylate metabolism
PATH: ec00910  Nitrogen metabolism
Orthology KO: K01455  formamidase
Genes ATH: AT4G37550 AT4G37560
OSA: 4326894(Os01g0764900)
PIC: PICST_28914(FRM1)
NCR: NCU02361
MGR: MGG_03533
ANI: AN4577.2
AFM: AFUA_2G02020
AOR: AO090011000472
ANG: An07g05830
PLU: plu3213(amiF)
PAY: PAU_03020(amiF)
PST: PSPTO_4073(fmdA)
PSB: Psyr_1166(amiF)
PFS: PFLU2534(fmdA)
SDE: Sde_2970
MAQ: Maqu_3860
TTU: TERTU_4262
TGR: Tgr7_3110
ABO: ABO_1978(fmdA)
REH: H16_B0072(fmdA1) H16_B0476(fmdA2)
BVI: Bcep1808_7168
BCN: Bcen_3737
BCH: Bcen2424_4631
BCM: Bcenmc03_5673
BXE: Bxe_B1706
BPE: BP1516(fmdA)
BPA: BPP1189(fmdA)
BBR: BB1405(fmdA)
BAV: BAV2261(fmdA)
POL: Bpro_0569
DAC: Daci_0179 Daci_0225
VAP: Vapar_3140
MPT: Mpe_A3592
HAR: HEAR1452
MMS: mma_1893(fmdA)
MFA: Mfla_1777
MEI: Msip34_0695
HPY: HP1238(amiF)
HPJ: jhp1159(amiF)
HPA: HPAG1_1180(amiF)
HPP: HPP12_1204(amiF)
HAC: Hac_1079(amiF)
DVU: DVU1164(amiF)
DVL: Dvul_1889(amiF)
RLE: pRL100351(amiF)
RLG: Rleg_0022
BJA: blr0972 blr6144(amiF)
BRA: BRADO6892(fmdA) BRADO7112(amiF)
BBT: BBta_0659(fmdA)
RPA: RPA1255(fmdA) RPA1923(amiF)
RPB: RPB_1257
RPD: RPD_3859
RPE: RPE_4597
RPT: Rpal_1448
OCA: OCAR_7088
MEX: Mext_1704(amiF) Mext_3375
MEA: Mex_1p3601(fmdA)
MDI: METDI2378(aimF) METDI4177(fmdA)
MRD: Mrad2831_5506
MET: M446_0598
MPO: Mpop_1114(amiF) Mpop_3566
MCH: Mchl_2023(amiF) Mchl_3684
BID: Bind_0981
RSP: RSP_3508
RDE: RD1_1494(fmdA) RD1_3602(fmdA)
PDE: Pden_3569
SWI: Swit_0965
GBE: GbCGDNIH1_1831
BAN: BA4149(amiF)
BAR: GBAA4149(amiF)
BAA: BA_4617
BAT: BAS3851(amiF)
BCE: BC3939(amiF)
BCZ: BCZK3699(amiF)
BTK: BT9727_3682(amiF)
BTL: BALH_3568(amiF)
GKA: GK1391
MSM: MSMEG_0484 MSMEG_3403(amiF) MSMEG_4367 MSMEG_5335
MAB: MAB_0587
MMC: Mmcs_2262
MKM: Mkms_2309
MJL: Mjls_2301
RHA: RHA1_ro02124 RHA1_ro03918
KRH: KRH_23000
SEN: SACE_1932
RXY: Rxyl_2658 Rxyl_2662
SYD: Syncc9605_2611(amiF) Syncc9605_2612
TRO: trd_A0546
HMA: pNG7060(fmdA)
NPH: NP6204A(fmdA)
HLA: Hlac_2285
MSE: Msed_0465
Taxonomy
Structures PDB: 2DYU  2DYV  2E2K  2E2L  
Reference
  Authors
  Title
  Journal
 1
Clarke, P.H.
The aliphatic amidases of Pseudomonas aeruginosa.
Adv. Microb. Physiol. 4 (1970) 179-222.
Reference
  Authors
  Title

  Journal
 2
Friedich, C.G. and Mitrenga, G.
Utilization of aliphatic amides and formation of two different
amidases by Alcaligenes eutrophus.
J. Gen. Microbiol. 125 (1981) 367-374.
Other DBs ExplorEnz - The Enzyme Database: 3.5.1.49
IUBMB Enzyme Nomenclature: 3.5.1.49
ExPASy - ENZYME nomenclature database: 3.5.1.49
BRENDA, the Enzyme Database: 3.5.1.49
CAS: 9013-59-6
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