| Entry |
|
|---|
| Name |
N,N-dimethylformamidase;
dimethylformamidase;
DMFase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
 |
|---|
| Sysname |
N,N-dimethylformamide amidohydrolase |
|---|
| Reaction(IUBMB) |
N,N-dimethylformamide + H2O = dimethylamine + formate [RN:R02509] |
|---|
| Reaction(KEGG) |
R02509
 |
|---|
| Substrate |
N,N-dimethylformamide [CPD:C03134];
H2O [CPD:C00001] |
|---|
| Product |
dimethylamine [CPD:C00543];
formate [CPD:C00058] |
|---|
| Cofactor |
Iron [CPD:C00023] |
|---|
| Comment |
An iron protein. Also acts on N-ethylformamide and
N-methyl-formamide and, more slowly, on N,N-diethylformamide,
N,N-dimethylacetamide and unsubstituted acyl amides. |
|---|
| Pathway |
PATH: ec00630 Glyoxylate and dicarboxylate metabolism |
|---|
| Orthology |
KO: K03418 N,N-dimethylformamidase |
|---|
| Genes |
BJA: blr3549 blr3932
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3732281]
Schar HP, Holzmann W, Ramos Tombo GM, Ghisalba O.
Purification and characterization of N,N-dimethylformamidase from
Pseudomonas DMF 3/3.
Eur. J. Biochem. 158 (1986) 469-75.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.1.56
IUBMB Enzyme Nomenclature: 3.5.1.56
ExPASy - ENZYME nomenclature database: 3.5.1.56
BRENDA, the Enzyme Database: 3.5.1.56
CAS: 104645-73-0 |
|---|
