KEGG   ENZYME: 3.5.1.6Help
Entry
EC 3.5.1.6                  Enzyme                                 

Name
beta-ureidopropionase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N-carbamoyl-beta-alanine amidohydrolase
Reaction(IUBMB)
N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3 [RN:R00905]
Reaction(KEGG)
Substrate
N-carbamoyl-beta-alanine [CPD:C02642];
H2O [CPD:C00001]
Product
beta-alanine [CPD:C00099];
CO2 [CPD:C00011];
NH3 [CPD:C00014]
Comment
The animal enzyme also acts on beta-ureidoisobutyrate.
Pathway
Pyrimidine metabolism
beta-Alanine metabolism
Pantothenate and CoA biosynthesis
Drug metabolism - other enzymes
Metabolic pathways
Orthology
K01431  
beta-ureidopropionase
Genes
HSA: 
51733(UPB1)
PTR: 
747532(UPB1)
PPS: 
100970346(UPB1)
GGO: 
101124006(UPB1)
PON: 
100172385(UPB1)
MCC: 
707752(UPB1)
MMU: 
103149(Upb1)
RNO: 
116593(Upb1)
CFA: 
486398(UPB1)
AML: 
100478175(UPB1)
FCA: 
101081004(UPB1)
BTA: 
504557(UPB1)
SSC: 
100155919(UPB1)
ECB: 
100053177(UPB1)
MDO: 
100013001(UPB1)
SHR: 
OAA: 
GGA: 
416949(UPB1)
MGP: 
TGU: 
100224765(UPB1)
ACS: 
XLA: 
447326(upb1)
XTR: 
100145317(upb1)
DRE: 
322660(upb1)
TRU: 
OLA: 
BFO: 
CIN: 
100187207(upb1)
SPU: 
DME: 
DAN: 
DER: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
NVI: 
100113520(NV16234) 100114526(NV16233)
TCA: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT5G64370(BETA-UP)
ALY: 
GMX: 
MTR: 
RCU: 
POP: 
VVI: 
OSA: 
BDI: 
SBI: 
SORBI_02g033430(SORBIDRAFT_02g033430)
ZMA: 
100283449(bas1)
SMO: 
PPP: 
CRE: 
VCN: 
CGR: 
PIC: 
NGR: 
DDI: 
TET: 
VFI: 
PPU: 
PST: 
PSB: 
PSP: 
BMA: 
BMAA1099(amaB-2)
BMV: 
BML: 
BMN: 
BPS: 
BPM: 
BPL: 
BPD: 
BTE: 
BXE: 
BPE: 
BPA: 
BBR: 
MLO: 
SME: 
ATU: 
Atu2385(amaB)
RET: 
RLE: 
RL3716(atcC)
BME: 
BMF: 
BMS: 
BMR: 
BJA: 
bll2919(amaB)
BBT: 
RPA: 
SIL: 
RSP: 
AAU: 
KRH: 
TTH: 
HMA: 
pNG7248(amaB)
 » show all
Taxonomy
Reference
1  [PMID:13849303]
  Authors
CAMPBELL LL.
  Title
Reductive degradation of pyrimidines. 5. Enzymatic conversion of N-carbamyl-beta-alanine to beta-alanine, carbon dioxide, and ammonia.
  Journal
J. Biol. Chem. 235 (1960) 2375-8.
  Organism
Clostridium uracilicum
Reference
2  [PMID:13538975]
  Authors
CARAVACA J, GRISOLIA S.
  Title
Enzymatic decarbamylation of carbamyl beta-alanine and carbamyl beta-aminoisobutyric acid.
  Journal
J. Biol. Chem. 231 (1958) 357-65.
  Organism
Rattus norvegicus [GN:rno]
Reference
3  [PMID:6433973]
  Authors
Traut TW, Loechel S.
  Title
Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay.
  Journal
Biochemistry. 23 (1984) 2533-9.
  Organism
Rattus norvegicus [GN:rno]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9027-27-4

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