KEGG   ENZYME: 3.5.1.68Help
Entry
EC 3.5.1.68                 Enzyme                                 
Name
N-formylglutamate deformylase;
beta-citryl-L-glutamate hydrolase;
formylglutamate deformylase;
N-formylglutamate hydrolase;
beta-citrylglutamate amidase;
beta-citryl-L-glutamate amidohydrolase;
beta-citryl-L-glutamate amidase;
beta-citryl-L-glutamate-hydrolyzing enzyme
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N-formyl-L-glutamate amidohydrolase
Reaction(IUBMB)
N-formyl-L-glutamate + H2O = formate + L-glutamate [RN:R00525]
Reaction(KEGG)
Substrate
N-formyl-L-glutamate [CPD:C01045];
H2O [CPD:C00001]
Product
formate [CPD:C00058];
L-glutamate [CPD:C00025]
Comment
The animal enzyme also acts on beta-citryl-L-glutamate and beta-citryl-L-glutamine.
Pathway
Histidine metabolism
Glyoxylate and dicarboxylate metabolism
Orthology
K01458  
N-formylglutamate deformylase
Genes
PSU: 
PFL: 
PFL_0410(hutG_2)
CPS: 
PHA: 
KKO: 
PSE: 
REU: 
REH: 
H16_A1109(hutG2) H16_A1306(hutG3) H16_A3013(hutG1) H16_A3649(hutG4)
RME: 
Rmet_0981(hutG) Rmet_2850(hutG1) Rmet_3507(hutG4)
CTI: 
CNC: 
CNE_1c29670(hutG3)
BMA: 
BMA0652(hutG) BMAA1476
BMV: 
BMASAVP1_A2360(hutG)
BML: 
BMA10229_2131 BMA10229_A2925(hutG)
BMN: 
BMA10247_1674(hutG) BMA10247_A0814
BPS: 
BPSL2338 BPSS0285
BPM: 
BURPS1710b_2790(hutG) BURPS1710b_A1827
BPL: 
BURPS1106A_2716(hutG) BURPS1106A_A0400
BPD: 
BURPS668_2660(hutG) BURPS668_A0498
BPR: 
GBP346_A2838(hutG)
BTE: 
BTH_I1826(hutG)
BVI: 
Bcep1808_2241
BUR: 
Bcep18194_A5476 Bcep18194_B0284
BCN: 
Bcen_5911
BCH: 
Bcen2424_2166
BCM: 
Bcenmc03_2183
BCJ: 
BCAL2240
BAM: 
Bamb_2205
BAC: 
BamMC406_2082
BMU: 
Bmul_1104
BMJ: 
BMULJ_02152(hutG)
BXE: 
Bxe_A2941
BPH: 
Bphy_1808
BPY: 
Bphyt_1536
BGL: 
bglu_1g25150
BUG: 
BC1001_1262
BGE: 
BC1002_1097
BGF: 
BC1003_2180 BC1003_6042
BGD: 
bgla_1g28420 bgla_2g03620
BBR: 
BB4732(hutG)
BAV: 
BAV0457(hutG)
AXY: 
AXYL_02574
RFR: 
Rfer_4155
POL: 
Bpro_1166 Bpro_2708
PNA: 
Pnap_2540
AAV: 
Aave_2959
AJS: 
Ajs_0856 Ajs_1666 Ajs_3995
DIA: 
Dtpsy_2038
AAA: 
Acav_2337
VEI: 
Veis_3650 Veis_4694
DAC: 
Daci_0156 Daci_5471
DEL: 
DelCs14_0158
VAP: 
Vapar_0166 Vapar_5206
VPE: 
Varpa_0192
CTT: 
CtCNB1_0175 CtCNB1_0782
ADN: 
Alide_2768
ADK: 
Alide2_1701
CFU: 
CFU_2384(hutG)
LCH: 
Lcho_0159
AZO: 
azo3002(hutG)
MEH: 
M301_1422
HOH: 
Hoch_1854
RET: 
RHE_CH03574
RLE: 
RL4092
BME: 
BMEII0049
BRA: 
BRADO6214
BBT: 
BBta_1390
RPE: 
RPE_0707
AEX: 
Astex_1519
SIL: 
SPOA0448(hutG)
RDE: 
RD1_0718(hutG)
HNE: 
HNE_2397(hutG)
ZMO: 
ZMO1181
GOX: 
GOX1165 GOX2197
GBE: 
GbCGDNIH1_0905
ACR: 
Acry_1751
GDI: 
GDI_2982
GDJ: 
Gdia_3369
RRU: 
Rru_A1300
RCE: 
RC1_3237(hutG)
CTM: 
Cabther_A1031
 » show all
Taxonomy
Reference
1  [PMID:3308850]
  Authors
Hu L, Mulfinger LM, Phillips AT.
  Title
Purification and properties of formylglutamate amidohydrolase from Pseudomonas putida.
  Journal
J. Bacteriol. 169 (1987) 4696-702.
  Organism
Pseudomonas putida
Reference
2  [PMID:6414521]
  Authors
Miyake M, Innami T, Kakimoto Y.
  Title
A beta-citryl-L-glutamate-hydrolysing enzyme in rat testes.
  Journal
Biochim. Biophys. Acta. 760 (1983) 206-14.
  Organism
Rattus norvegicus [GN:rno]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
97286-12-9
DBGET integrated database retrieval system