KEGG   ENZYME: 3.5.3.11Help
Entry
EC 3.5.3.11                 Enzyme                                 
Name agmatinase;
agmatine ureohydrolase;
SpeB
Class Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
BRITE hierarchy
Sysname agmatine amidinohydrolase
Reaction(IUBMB) agmatine + H2O = putrescine + urea [RN:R01157]
Reaction(KEGG) R01157
Show
Substrate agmatine [CPD:C00179];
H2O [CPD:C00001]
Product putrescine [CPD:C00134];
urea [CPD:C00086]
Pathway PATH: ec00330  Arginine and proline metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K01480  agmatinase
Genes HSA: 79814(AGMAT)
PTR: 469130(AGMAT)
MCC: 713190
MMU: 75986(Agmat)
RNO: 298607(Agmat)
CFA: 487430(AGMAT)
BTA: 514509(AGMAT)
ECB: 100054283
MDO: 100027134
OAA: 100093512
GGA: 373942(AGMAT)
TGU: 100229337
XLA: 734257
DRE: 556522
CIN: 100177356 100180543
SPU: 577889
NVE: NEMVE_v1g211198
POP: POPTR_572088
RCU: RCOM_1611220
VVI: 100245397
SBI: SORBI_06g000580(SORBIDRAFT_06g000580)
ZMA: 100272721
PPP: PHYPADRAFT_234776
AGO: AGOS_AFR048W
KLA: KLLA0F04235g KLLA0F27995g
LTH: KLTH0B06006g KLTH0C07502g
DHA: DEHA0B10615g DEHA0G00979g
PIC: PICST_32515(SPB2) PICST_55948(CAR12)
LEL: LELG_04769
ZRO: ZYRO0A03080g ZYRO0G05610g
CAL: CaO19.13284(AFP99) CaO19.3418(AFP98)
CTP: CTRG_02326 CTRG_02328 CTRG_02870
CDU: CD36_61780 CD36_84150
YLI: YALI0E04202g
SPO: SPAC11D3.09 SPBC8E4.03
NCR: NCU01348 NCU02084 NCU11320
PAN: PODANSg4119 PODANSg7908
MGR: MGG_10533 MGG_11574
FGR: FG02206.1 FG05446.1
ANI: AN6869.2 AN7488.2 AN7669.2
AFM: AFUA_2G05750 AFUA_5G13180
AOR: AO090001000694 AO090120000455 AO090701000422
ANG: An01g15140 An02g14210 An03g05070 An14g05960
AFV: AFLA_058810 AFLA_094280 AFLA_129920
PCS: Pc16g13170 Pc21g06570 Pc22g09020
NFI: NFIA_073850 NFIA_082470
CIM: CIMG_00177 CIMG_00787
URE: UREG_00281 UREG_00755
SSL: SS1G_05210 SS1G_13725
BFU: BC1G_09029 BC1G_12157 BC1G_15520
CNE: CND03500
CNB: CNBD2830
LBC: LACBIDRAFT_305021
MPR: MPER_08303 MPER_11413
UMA: UM01858.1
PTM: GSPATT00012871001
LMA: LmjF23.0070
LIF: LinJ23.0080
LBZ: LbrM23_V2.0080
ECO: b2937(speB)
ECJ: JW2904(speB)
ECD: ECDH10B_3112(speB)
EBW: BWG_2659(speB)
ECE: Z4281(speB)
ECS: ECs3812
ECF: ECH74115_4239(speB)
ETW: ECSP_3907(speB)
ECG: E2348C_3189(speB)
ECC: c3522(speB)
ECI: UTI89_C3325(speB)
ECP: ECP_2931
ECV: APECO1_3592(speB)
ECW: EcE24377A_3279(speB)
ECX: EcHS_A3095(speB)
ECM: EcSMS35_3079(speB)
ECY: ECSE_3205
ECL: EcolC_0774
ECK: EC55989_3229(speB)
ECQ: ECED1_3399(speB)
ECR: ECIAI1_3069(speB)
ECT: ECIAI39_3356(speB)
ECZ: ECS88_3219(speB)
EUM: ECUMN_3288(speB)
ELF: LF82_2158(speB)
EBL: B21_02730(speB)
EBD: ECBD_0801
EBR: ECB_02767(speB)
EOH: ECO103_3517(speB)
EOI: ECO111_3684(speB)
EOJ: ECO26_4035(speB)
EFE: EFER_2871(speB)
STY: STY3238(speB)
STT: t2998(speB)
SPT: SPA2949(speB)
SEK: SSPA2748
SPQ: SPAB_03838
SEI: SPC_3141(speB)
SEC: SC3020(speB)
SEH: SeHA_C3316(speB)
SEE: SNSL254_A3324(speB)
SEW: SeSA_A3258(speB)
SEA: SeAg_B3240(speB)
SED: SeD_A3420(speB)
SEG: SG2973(speB)
SET: SEN2921(speB)
SES: SARI_04560
STM: STM3078(speB)
SFL: SF2927(speB)
SFX: S3129(speB)
SFV: SFV_2989(speB)
SSN: SSON_3091(speB)
SBO: SBO_3052(speB)
SBC: SbBS512_E3370(speB)
SDY: SDY_3139(speB)
ETA: ETA_28230(speB)
PLU: plu3680(speB)
PAY: PAU_01089(speB)
SGL: SG2017
ENT: Ent638_3343
ESA: ESA_00403
CTU: Ctu_34740(speB)
KPN: KPN_02973 KPN_03373(speB)
KPE: KPK_0738(speB) KPK_1158
KPU: KP1_4232 KP1_4648(speB)
CKO: CKO_04314
SPE: Spro_1619 Spro_3972
PMR: PMI2093(speB)
EIC: NT01EI_3373
ETR: ETAE_2962(speB)
BFL: Bfl253(speB)
BPN: BPEN_260(speB)
PMU: PM1381(speE)
VCH: VCA0814
VCO: VC0395_0420(speB)
VCM: VCM66_A0773(speB)
VCJ: VCD_000510
VVU: VV1_2355
VVY: VV1987
VPA: VPA0169
VHA: VIBHAR_06738
VSP: VS_1239(speB)
VEX: VEA_000829
VFI: VF_A0839(speB)
VFM: VFMJ11_A0970(speB)
PAE: PA0288(gpuA)
PAU: PA14_03770(speB1)
PAP: PSPA7_0379(speB2)
PAG: PLES_02841(gpuA)
PPU: PP_2196(speB)
PPF: Pput_3541
PPG: PputGB1_1820 PputGB1_3103
PFL: PFL_0325
PFO: Pfl01_2576
PEN: PSEEN3509(speB)
PMY: Pmen_4051
SDN: Sden_2278
SLO: Shew_1621
SSE: Ssed_2607
SPL: Spea_2478
SHL: Shal_1805
SWD: Swoo_2059
SWP: swp_3022
ILO: IL1212(speB)
CPS: CPS_0384(speB) CPS_1196
PHA: PSHAa1076(speB) PSHAb0317
PIN: Ping_0860
CBU: CBU_0720
CBS: COXBURSA331_A0838(speB)
CBD: CBUD_0733(speB)
CBG: CbuG_1282(sepB)
CBC: CbuK_1536(sepB)
HNA: Hneap_2384
HCH: HCH_03622
CSA: Csal_2838
NMA: NMA2016(speB)
NME: NMB0469(speE)
NMC: NMC1680(speB)
NMN: NMCC_1673(speB)
NMI: NMO_1573(speB)
NGO: NGO1486
NGK: NGK_1758
CVI: CV_0490(speB)
LHK: LHK_01140(speB)
RSO: RSp1578(speB)
RPF: Rpic12D_2148
REU: Reut_B5705
BMA: BMAA1597(speB)
BML: BMA10229_1996(speB)
BMN: BMA10247_A0674(speB)
BPS: BPSS0474(speB) BPSS1587(speB)
BPM: BURPS1710b_A0639 BURPS1710b_A2027
BPL: BURPS1106A_A0643(speB) BURPS1106A_A2157(speB)
BPD: BURPS668_A0735(speB) BURPS668_A2243(speB)
BTE: BTH_II0784 BTH_II1941
BVI: Bcep1808_3536 Bcep1808_5199
BUR: Bcep18194_A4379 Bcep18194_B0366 Bcep18194_B1147 Bcep18194_B2787
BCN: Bcen_3083 Bcen_3696
BCH: Bcen2424_4672 Bcen2424_5284
BCM: Bcenmc03_4984 Bcenmc03_5628
BCJ: BCAL1218(speB) BCAM0416(AGMAT) BCAM1812 BCAM2482(speB) BCAS0132
BAM: Bamb_4066 Bamb_4644
BAC: BamMC406_4524 BamMC406_5173
BMU: Bmul_3436 Bmul_5199
BMJ: BMULJ_03320(speB) BMULJ_05080(speB)
BXE: Bxe_A3438 Bxe_B0946
BPH: Bphy_0638 Bphy_6083
BPY: Bphyt_1041 Bphyt_5361 Bphyt_6362
BGL: bglu_2g04100
BPE: BP1531
BPA: BPP1203 BPP2778
BBR: BB1420 BB2707
BAV: BAV0895
RFR: Rfer_0346 Rfer_0597
POL: Bpro_2025
PNA: Pnap_2635
VEI: Veis_0334
DAC: Daci_5122
VAP: Vapar_4700
MPT: Mpe_A1890
NEU: NE1147
NET: Neut_1437 Neut_2187
ABU: Abu_1569(speB)
GUR: Gura_2353
GBM: Gbem_0545
GEM: GM21_0557
DVU: DVU0421
DVL: Dvul_2513
DDE: Dde_0574
DDS: Ddes_0074
DBA: Dbac_1609
DRT: Dret_1313
BBA: Bd0356 Bd3436(speB)
DPS: DP1391
DAL: Dalk_3765
DAT: HRM2_01390(speB)
ADE: Adeh_2584 Adeh_4101
ACP: A2cp1_1365 A2cp1_4251
AFW: Anae109_0327 Anae109_1275
ANK: AnaeK_1264 AnaeK_4226
MXA: MXAN_4431
SCL: sce0044(speB1) sce4400 sce6911 sce9154(speB2)
SAT: SYN_01147
SFU: Sfum_0721
PUB: SAR11_0206(speB1) SAR11_1329(speB)
MLO: mll0412 mll8453 mlr4895
MES: Meso_1162
SME: SMc01802(speB) SMc01967(speB2)
SMD: Smed_0860 Smed_2410
ATU: Atu1245(speB)
ATC: AGR_C_2296
ARA: Arad_1805(speB) Arad_7959(speB) Arad_9121(speB)
     Arad_9511(speB2)
AVI: Avi_1009(speB) Avi_1675(speB) Avi_2237 Avi_2473(speB)
RET: RHE_CH01568(speB1) RHE_CH02143(speB2)
REC: RHECIAT_CH0001637(speBch1) RHECIAT_CH0002201(speBch2)
     RHECIAT_PC0000732(speBc)
RLE: RL1669(speB) RL2427 RL4455(speB) pRL100366(agmaT)
RLT: Rleg2_1231 Rleg2_1777 Rleg2_4643 Rleg2_4872
RLG: Rleg_1319 Rleg_1954 Rleg_3988 Rleg_6439
RHI: NGR_b03870 NGR_b04590 NGR_c10200 NGR_c25370(speB)
BME: BMEI0110 BMEI1170
BMF: BAB1_0809 BAB1_1958
BMB: BruAb1_0803 BruAb1_1933
BMC: BAbS19_I07570 BAbS19_I18360
BMS: BR0789 BR1957
BMT: BSUIS_A0826(speB) BSUIS_A1797(pah)
BOV: BOV_0784(speB) BOV_1883
BCS: BCAN_A0802(speB) BCAN_A2002(pah)
BMR: BMI_I1979 BMI_I789
OAN: Oant_2499 Oant_4509
BRA: BRADO6795
BBT: BBta_0743
XAU: Xaut_3492
AZC: AZC_1206
MEX: Mext_3924
MEA: Mex_1p4303
MDI: METDI4914
MET: M446_6964
MPO: Mpop_4397
MCH: Mchl_4292
MNO: Mnod_7678
SIL: SPO0599(speB-1) SPO0678 SPO2464(speB-2) SPO2467(speB-3)
     SPOA0235(speB-4)
SIT: TM1040_0938 TM1040_0939
RSP: RSP_2909 RSP_3743(speB1)
RSH: Rsph17029_1554 Rsph17029_3474
RSQ: Rsph17025_1111
RSK: RSKD131_1227 RSKD131_3977
JAN: Jann_0277 Jann_1967 Jann_2340
RDE: RD1_2715 RD1_3130 RD1_3131
PDE: Pden_1151 Pden_5116
DSH: Dshi_1735(speB)
ACR: Acry_2769
MAG: amb1100
MGM: Mmc1_3564
BSU: BSU37490(speB)
BHA: BH3810
BAN: BA5617
BAR: GBAA5617
BAA: BA_0473
BAT: BAS5218
BAH: BAMEG_5661
BAI: BAA_5643
BCE: BC5370
BCA: BCE_5498
BCZ: BCZK5066(speB)
BCR: BCAH187_A5547
BCB: BCB4264_A5491
BCU: BCAH820_5461
BCG: BCG9842_B5460
BCQ: BCQ_5209(speB)
BCX: BCA_5519
BCY: Bcer98_3883
BTK: BT9727_5050(speB)
BTL: BALH_4866(speB)
BWE: BcerKBAB4_5163
BLI: BL03921(speB)
BLD: BLi03973(speB)
BCL: ABC1178 ABC3897(speB)
BAY: RBAM_034610(speB)
BPU: BPUM_3386(speB)
OIH: OB2551
GKA: GK3404
GTN: GTNG_1830 GTNG_3349
GWC: GWCH70_3350
GYM: GYMC10_0102
GYC: GYMC61_2757 GYMC61_3460
AFL: Aflv_0218(speB) Aflv_2749(speB)
SSP: SSP2175
LSP: Bsph_0957
ESI: Exig_0251
EAT: EAT1b_1382
MCL: MCCL_1664
BBE: BBR47_55070(speB)
AAC: Aaci_2793
STC: str0921(speB)
STL: stu0921(speB)
STE: STER_0938
CPE: CPE0551(speB)
CPF: CPF_0530(speB)
CPR: CPR_0516(speB)
CTH: Cthe_0695
CDF: CD0891(speB)
CDC: CD196_0841(speB)
CDL: CDR20291_0821(speB)
CBK: CLL_A1017(speB)
CBT: CLH_0951(speB)
CKL: CKL_2407(speB)
CKR: CKR_2123
CPY: Cphy_3053
CCE: Ccel_2434
AMT: Amet_2650
AOE: Clos_1585
STH: STH18
SWO: Swol_0669
ATE: Athe_1315
DSY: DSY0233
DHD: Dhaf_0178
DRM: Dred_0489
DAE: Dtox_3566
PTH: PTH_0946(speB)
DAU: Daud_1978
TTE: TTE1335(speB)
TEX: Teth514_1581
TPD: Teth39_1144
CHY: CHY_1620
MTA: Moth_1815
ADG: Adeg_0207
CSC: Csac_1880
NTH: Nther_2759
ACL: ACL_1316(speB)
MSM: MSMEG_1072(speB) MSMEG_3535(speB) MSMEG_4374(speB)
     MSMEG_4459(speB)
MVA: Mvan_0046 Mvan_0161 Mvan_0814 Mvan_3024
MGI: Mflv_0094 Mflv_0797 Mflv_3303
MMC: Mmcs_1825 Mmcs_2256 Mmcs_2734 Mmcs_3024 Mmcs_3283 Mmcs_5283
MKM: Mkms_1872 Mkms_2303 Mkms_2778 Mkms_3083 Mkms_3345 Mkms_5372
MJL: Mjls_1806 Mjls_2295 Mjls_2764 Mjls_3040 Mjls_3294 Mjls_5662
RHA: RHA1_ro03527
RER: RER_05760(speB)
ROP: ROP_26680(speB) ROP_33210(speB)
SCO: SCO2770(SCC105.01c)
SMA: SAV_5285(speB)
SGR: SGR_4788
ART: Arth_0851
AAU: AAur_1058 AAur_4009
ACH: Achl_0967
RSA: RSal33209_0215
KRH: KRH_21350(speB)
MLU: Mlut_04350
NCA: Noca_3224 Noca_3382
TFU: Tfu_0058
SRO: Sros_1877
FRA: Francci3_0848
FRE: Franean1_5671
NML: Namu_0285 Namu_2950 Namu_4832
KRA: Krad_1433
SEN: SACE_6015 SACE_6017(speB)
SVI: Svir_33400
CAI: Caci_8153
RXY: Rxyl_2907
AFO: Afer_0273
CPI: Cpin_3076
GFO: GFO_3624(speB)
FPS: FP2214(speB)
FBA: FIC_02262
COC: Coch_2044
RBI: RB2501_05260 RB2501_12057
BBL: BLBBGE_059(rocF)
BPI: BPLAN_574(speB)
AAS: Aasi_1151
LBA: Lebu_1823
EMI: Emin_1538
SYN: sll0228 sll1077(speB)
SYW: SYNW1412 SYNW2422
SYD: Syncc9605_1082 Syncc9605_2591
SYE: Syncc9902_2230
SYG: sync_2851(speB)
SYR: SynRCC307_2435(speB) SynRCC307_2478(speB)
SYX: SynWH7803_2454(speB)
SYP: SYNPCC7002_A1109(speB) SYNPCC7002_A1751
CYA: CYA_0535 CYA_0859(speB)
CYB: CYB_1744(speB) CYB_2252
MAR: MAE_18840 MAE_47100
CYC: PCC7424_2696 PCC7424_5245
GVI: gll3725
ANA: alr2310
NPU: Npun_R6035
AVA: Ava_0127
PMA: Pro1849(speB)
PMM: PMM1686
PMT: PMT2214
PMN: PMN2A_1287
PMI: PMT9312_1779
PMB: A9601_18961(speB)
PMC: P9515_18771(speB)
PMF: P9303_29511(speB)
PMG: P9301_18771(speB)
PMH: P9215_19591(speB)
PMJ: P9211_18171(speB)
PME: NATL1_21591(speB)
TER: Tery_3780
AMR: AM1_2833(speB) AM1_3528(speB)
RRS: RoseRS_3007
RCA: Rcas_2108
HAU: Haur_4857
TRO: trd_0528 trd_A0748
STI: Sthe_0645
DRA: DR_A0149
DGE: Dgeo_2732
DDR: Deide_15240
TTH: TTC0764
TTJ: TTHA1129
TLE: Tlet_1302
DTH: DICTH_1308
DTU: Dtur_1414
MJA: MJ0309
MFE: Mefer_0143
MVU: Metvu_0240
MMP: MMP1585
MMQ: MmarC5_1824
MMX: MmarC6_1085
MMZ: MmarC7_0832
MAE: Maeo_1446
MVN: Mevan_0897
MAC: MA3986
MBA: Mbar_A0694
MMA: MM_0923
MBU: Mbur_1896
MLA: Mlab_0425
MEM: Memar_0965
MBN: Mboo_2035
MPL: Mpal_2336
MPD: MCP_1739(speB)
MTH: MTH868
MST: Msp_0415
MSI: Msm_0876
MKA: MK0738
AFU: AF0646(speB)
HAL: VNG1767G(speB)
HSL: OE2736F(hutG) OE3486R(speB)
HMA: pNG7067(speB2) rrnAC1927(speB1)
HWA: HQ3349A(speB)
NPH: NP3022A(speD_1)
HLA: Hlac_1577
HUT: Huta_2580
HMU: Hmuk_1603
TAC: Ta1058
TVO: TVN0538
PHO: PH0083
PAB: PAB0050(speB)
PFU: PF1957
TKO: TK0882
TON: TON_0425
TGA: TGAM_0431(speB)
TSI: TSIB_0246 TSIB_1067
RCI: LRC54(speB)
APE: APE_0316.1 APE_1637.1(speB)
SMR: Smar_1135
IHO: Igni_1371
DKA: DKAM_0053
HBU: Hbut_0051
SSO: SSO0445(speB-1) SSO2732(speB-2)
STO: ST0352
SAI: Saci_0863 Saci_2134
SIS: LS215_1789 LS215_2751
SIA: M1425_1661 M1425_2592
SIM: M1627_1777 M1627_2645
SID: M164_1709 M164_2576
SIY: YG5714_1778 YG5714_2758
SIN: YN1551_0132 YN1551_1149
MSE: Msed_0497 Msed_2212
PAI: PAE2260
PIS: Pisl_0897
PCL: Pcal_1626
PAS: Pars_1481 Pars_1823
CMA: Cmaq_1543 Cmaq_1584
TNE: Tneu_1431
TPE: Tpen_0509
NMR: Nmar_0925
NEQ: NEQ223
KCR: Kcr_0285 Kcr_1289
Taxonomy
Structures PDB: 1GQ6  1GQ7  1WOG  1WOH  1WOI  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:4908780]
Hirshfield IN, Rosenfeld HJ, Leifer Z, Maas WK.
Isolation and characterization of a mutant of Escherichia coli
blocked in the synthesis of putrescine.
J. Bacteriol. 101 (1970) 725-30.
Escherichia coli [GN:eco]
Reference
  Authors
  Title

  Journal
 2
Vicente, C. and Legaz, M.E.
Preparation and properties of agmatine amidinohydrolase of Evernia
prunastri.
Physiol. Plant. 55 (1982) 335-339.
Other DBs ExplorEnz - The Enzyme Database: 3.5.3.11
IUBMB Enzyme Nomenclature: 3.5.3.11
ExPASy - ENZYME nomenclature database: 3.5.3.11
BRENDA, the Enzyme Database: 3.5.3.11
CAS: 37289-16-0
DBGET integrated database retrieval system