| Entry |
|
|---|
| Name |
creatinase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
 |
|---|
| Sysname |
creatine amidinohydrolase |
|---|
| Reaction(IUBMB) |
creatine + H2O = sarcosine + urea [RN:R01566] |
|---|
| Reaction(KEGG) |
R01566
 |
|---|
| Substrate |
creatine [CPD:C00300];
H2O [CPD:C00001] |
|---|
| Product |
sarcosine [CPD:C00213];
urea [CPD:C00086] |
|---|
| Pathway |
PATH: ec00260 Glycine, serine and threonine metabolism
PATH: ec00330 Arginine and proline metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K08688 creatinase |
|---|
| Genes |
ABY: p3ABAYE0029
BVI: Bcep1808_7033
BPH: Bphy_6284
PUB: SAR11_0687(pepQ)
SIL: SPO3327
SIT: TM1040_2491
RSP: RSP_1752
RSH: Rsph17029_0398
RSQ: Rsph17025_2498
RSK: RSKD131_0051
JAN: Jann_2612
RDE: RD1_0929(cln)
ART: Arth_3728
AAU: AAur_3822
ACH: Achl_3303
KRH: KRH_03000
RXY: Rxyl_0461
 |
|---|
| Structures |
PDB: 1CHM 1KP0 |
|---|
Reference
Authors
Title
Journal
|
1 [PMID:14791411]
ROCHE J, LACOMBE G, GIRARD H.
[On the specificity of certain bacterial deguanidases generating
urea and on arginindihydrolase.]
Biochim. Biophys. Acta. 6 (1950) 210-6. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:8443]
Yoshimoto T, Oka I, Tsuru D.
Purification, crystallization, and some properties of creatine
amidinohydrolase from Pseudomonas putida.
J. Biochem. (Tokyo). 79 (1976) 1381-3.
Pseudomonas putida |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.3.3
IUBMB Enzyme Nomenclature: 3.5.3.3
ExPASy - ENZYME nomenclature database: 3.5.3.3
BRENDA, the Enzyme Database: 3.5.3.3
CAS: 37340-58-2 |
|---|
