| Entry |
|
|---|
| Name |
dCMP deaminase;
deoxycytidylate deaminase;
deoxy-CMP-deaminase;
deoxycytidylate aminohydrolase;
deoxycytidine monophosphate deaminase;
deoxycytidine-5'-phosphate deaminase;
deoxycytidine-5'-monophosphate aminohydrolase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
 |
|---|
| Sysname |
dCMP aminohydrolase |
|---|
| Reaction(IUBMB) |
dCMP + H2O = dUMP + NH3 [RN:R01663] |
|---|
| Reaction(KEGG) |
R01663;
(other) R06137
 |
|---|
| Substrate |
dCMP [CPD:C00239];
H2O [CPD:C00001] |
|---|
| Product |
dUMP [CPD:C00365];
NH3 [CPD:C00014] |
|---|
| Comment |
Also acts on some 5-substituted dCMPs. |
|---|
| Pathway |
PATH: ec00240 Pyrimidine metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K01493 dCMP deaminase |
|---|
| Genes |
HSA: 1635(DCTD)
PTR: 461620(DCTD)
MCC: 700995(DCTD)
MMU: 320685(Dctd)
RNO: 290741(Dctd)
CFA: 607328(DCTD)
BTA: 784292(DCTD)
SSC: 100154836
ECB: 100051279(DCTD)
MDO: 100016351
OAA: 100091521
GGA: 422556(DCTD)
TGU: 100227016
XLA: 414581
XTR: 549019
DRE: 550332(dctd)
CIN: 100185358
SPU: 575919 580835
DME: Dmel_CG6951
DPO: Dpse_GA19978
DAN: Dana_GF25318
DER: Dere_GG16092
DPE: Dper_GL25124
DSE: Dsec_GM22266
DSI: Dsim_GD14864
DYA: Dyak_GE19654
DGR: Dgri_GH15113
DMO: Dmoj_GI13764
AGA: AgaP_AGAP008158
AAG: AaeL_AAEL014287
CQU: CpipJ_CPIJ004863
AME: 408883
NVI: 100118441
TCA: 662313
API: 100160379
CEL: ZK643.2
CBR: CBG06863
BMY: Bm1_28380
SMM: Smp_009530
NVE: NEMVE_v1g233184
HMG: 100197850
TAD: TRIADDRAFT_50803
ATH: AT3G48540
POP: POPTR_575360
RCU: RCOM_1506180
VVI: 100261131(GSVIVT00017944001)
OSA: 4326895(Os01g0765000)
SBI: SORBI_03g035540(SORBIDRAFT_03g035540)
ZMA: 100285892
PPP: PHYPADRAFT_6902
CRE: CHLREDRAFT_154823
OLU: OSTLU_8218
CME: CMQ291C
SCE: YHR144C(DCD1)
AGO: AGOS_AFR023W
KLA: KLLA0D08074g
LTH: KLTH0B06776g
DHA: DEHA0D05313g
PIC: PICST_34441(DCD1)
PPA: PAS_chr1-1_0163
VPO: Kpol_1051p30
LEL: LELG_03636
ZRO: ZYRO0G04972g
CTP: CTRG_03707
CDU: CD36_13280
CGR: CAGL0G05852g
YLI: YALI0C23210g
SPO: SPBC2G2.13c
NCR: NCU06673
PAN: PODANSg7964
FGR: FG10227.1
ANI: AN7429.2
AFM: AFUA_2G06240
AOR: AO090001000741 AO090001000742
ANG: An02g14880
AFV: AFLA_130400
PCS: Pc21g11370
NFI: NFIA_083030
CIM: CIMG_04268
SSL: SS1G_05018
BFU: BC1G_09810
CNE: CNB00950
CNB: CNBB4760
LBC: LACBIDRAFT_228936
MGL: MGL_2270
MBR: MONBRDRAFT_3136 MONBRDRAFT_33129
CPV: cgd2_2780
CHO: Chro.20294
TGO: TGME49_000420
TET: TTHERM_00498180
PTM: GSPATT00031368001
PTI: PHATRDRAFT_9348
TPS: THAPS_42740
XCC: XCC0126
XCB: XC_0132
VCH: VCA0840
VCO: VC0395_0395
VCM: VCM66_A0799
VCJ: VCD_000487
VVU: VV2_0531
VVY: VVA1080
VPA: VPA1192
VHA: VIBHAR_05385
VSP: VS_II1145
VEX: VEA_000505
VFI: VF_A0917
VFM: VFMJ11_A1035
VSA: VSAL_II0956
PPR: PBPRB1018
SDN: Sden_0078
SFR: Sfri_3571
SLO: Shew_3055
SSE: Ssed_3657
SPL: Spea_3277
SHL: Shal_3351
SWD: Swoo_3945
SWP: swp_0954
PHA: PSHAa1256
CBU: CBU_1374
RMA: Rmag_0308
VOK: COSY_0290
REH: H16_B0797
DAC: Daci_3412
MPT: Mpe_A1200 Mpe_B0197
TDN: Suden_0147
ABU: Abu_0039
GSU: GSU1686
GME: Gmet_1622
GUR: Gura_2185
GLO: Glov_1747
GBM: Gbem_3026
GEO: Geob_2673
GEM: GM21_1224
PCA: Pcar_1443
PPD: Ppro_1598
DVU: DVU1202
DVL: Dvul_1855
DVM: DvMF_3096
DDE: Dde_2433
DDS: Ddes_1618
DMA: DMR_05630(dcd)
DSA: Desal_0656
DBA: Dbac_0063
DRT: Dret_1419
DPS: DP2271
DOL: Dole_2081
DAL: Dalk_0201
DAT: HRM2_31290
ADE: Adeh_1552
ACP: A2cp1_2401
AFW: Anae109_2261
ANK: AnaeK_2313
MXA: MXAN_4044
SCL: sce9015(comEB)
HOH: Hoch_4494
SAT: SYN_02368
SFU: Sfum_0680 Sfum_1248
JAN: Jann_3746
MAG: amb2697
MGM: Mmc1_1393
BSU: BSU25580(comEB)
BHA: BH1334(comEB)
BAN: BA4552(comEB)
BAR: GBAA4552(comEB)
BAA: BA_4997
BAT: BAS4224
BAH: BAMEG_4589(comEB)
BAI: BAA_4571(comEB)
BCE: BC4323
BCA: BCE_4407(comEB)
BCZ: BCZK4072(comEB)
BCR: BCAH187_A4459(comEB)
BCB: BCB4264_A4446(comEB)
BCU: BCAH820_4348(comEB)
BCG: BCG9842_B0791(comEB)
BCQ: BCQ_4112(comEB)
BCX: BCA_4437(comEB)
BCY: Bcer98_3052
BTK: BT9727_4062(comEB)
BTL: BALH_3914(comEB)
BWE: BcerKBAB4_4177
BLI: BL02086(comEB)
BLD: BLi02751(comEB)
BCL: ABC1647(comEB)
BAY: RBAM_023880(comEB)
BPU: BPUM_2292(comEB)
OIH: OB1980
GKA: GK2516(comEB)
GTN: GTNG_2452(comEB)
GWC: GWCH70_2450
GYM: GYMC10_1724
GYC: GYMC61_1001
AFL: Aflv_0821(comEB)
SAU: SA1417(comEB)
SAV: SAV1589(comEB)
SAW: SAHV_1576(comEB)
SAM: MW1540(comEB)
SAR: SAR1666
SAS: SAS1526
SAC: SACOL1645
SAB: SAB1461c
SAA: SAUSA300_1548
SAX: USA300HOU_1590(comEB)
SAO: SAOUHSC_01692
SAJ: SaurJH9_1646
SAH: SaurJH1_1681
SAE: NWMN_1491(comEB)
SAD: SAAV_1580
SEP: SE1275
SER: SERP1156
SHA: SH1326(comEB)
SSP: SSP1169
SCA: Sca_1211
LMO: lmo1483(comEB)
LMF: LMOf2365_1502
LMH: LMHCC_1087
LMC: Lm4b_01493(comEB)
LIN: lin1518
LWE: lwe1496(comEB)
LSP: Bsph_3843
ESI: Exig_1750
EAT: EAT1b_0078
MCL: MCCL_1239(comEB)
PJD: Pjdr2_2193
AAC: Aaci_0194
LLA: L155044(dcdA)
LLK: LLKF_1166(dcdA)
LLC: LACR_1252
LLM: llmg_1416
SPY: SPy_1823(comEB)
SPZ: M5005_Spy_1548(comEB)
SPM: spyM18_1888
SPG: SpyM3_1575(comEB)
SPS: SPs0292
SPH: MGAS10270_Spy1615(comEB)
SPI: MGAS10750_Spy1607(comEB)
SPJ: MGAS2096_Spy1573(comEB)
SPK: MGAS9429_Spy1552(comEB)
SPF: SpyM50302
SPA: M6_Spy1537
SPB: M28_Spy1535(comEB)
SOZ: Spy49_1421c(comEB)
SPN: SP_0744
SPD: SPD_0648
SPR: spr0654(comEB)
SPW: SPCG_0694
SPX: SPG_0675
SNE: SPN23F_06680
SPV: SPH_0846
SNM: SP70585_0790
SJJ: SPJ_0683
SPP: SPP_0755
SNT: SPT_0759
SAG: SAG1704
SAN: gbs1750
SAK: SAK_1713
SMU: SMU.1849(comEB)
STC: str1741(comEB)
STL: stu1741(comEB)
STE: STER_1716
SSA: SSA_1497(comEB)
SSU: SSU05_1622
SSV: SSU98_1633
SSB: SSUBM407_1512
SSI: SSU1436
SSS: SSUSC84_1465
SGO: SGO_0981
SEQ: SZO_16250
SEZ: Sez_0351(comEB)
SEU: SEQ_0418
SUB: SUB1549
SDS: SDEG_1877(comEB)
LPL: lp_2130(comEB)
LPJ: JDM1_1785(comEB)
LJO: LJ0199
LJF: FI9785_275
LAC: LBA0210
LSA: LSA1070
LSL: LSL_0679(comEB)
LDB: Ldb0339
LBU: LBUL_0294
LBR: LVIS_1396
LCB: LCABL_17040(comEB)
LGA: LGAS_0202
LRE: Lreu_0644
LRF: LAR_0621
LHE: lhv_2211
LFE: LAF_0609
LRH: LGG_01488(comEB)
LRL: LC705_01503(comEB)
PPE: PEPE_1150
EFA: EF2448
LME: LEUM_0459
LCI: LCK_01323(comEB)
CAC: CAC2876
CPE: CPE1066
CPF: CPF_1322
CPR: CPR_1134
CTC: CTC00309
CNO: NT01CX_0541
CTH: Cthe_2599
CDF: CD1899 CD3477
CDC: CD196_1774 CD196_3267
CDL: CDR20291_1819 CDR20291_3313
CBO: CBO0146
CBA: CLB_0182
CBH: CLC_0194
CBY: CLM_0190
CBL: CLK_3321
CBK: CLL_A0488
CBB: CLD_0639
CBI: CLJ_B0185
CBT: CLH_0480
CBF: CLI_0201
CBE: Cbei_0409
CKL: CKL_3701
CKR: CKR_3266
CPY: Cphy_0189
CCE: Ccel_0261
AMT: Amet_0340
AOE: Clos_2571
STH: STH80
SWO: Swol_2391
VPR: Vpar_0963
ATE: Athe_0634
DSY: DSY4925
DHD: Dhaf_4824
DRM: Dred_3161
DAE: Dtox_4176
PTH: PTH_2823(ComEB)
DAU: Daud_1943
HMO: HM1_1092(comE)
FMA: FMG_1571
APR: Apre_0433
EEL: EUBELI_01938
ERE: EUBREC_0115
TTE: TTE0148(comEB)
TEX: Teth514_0100
TPD: Teth39_2103
CHY: CHY_2556
MTA: Moth_2389
ADG: Adeg_0072
CSC: Csac_1202
NTH: Nther_2856
MPU: MYPU_2780(dctD)
MGA: MGA_0701(folA)
MMY: MSC_0581(dctD)
MMO: MMOB5300(comEB)
MSY: MS53_0396(comEB)
MCP: MCAP_0397
MAT: MARTH_orf406(dctD)
MHO: MHO_1500
ACL: ACL_0821(comEB)
MFL: Mfl385
ACH: Achl_4254
PAC: PPA1950
RXY: Rxyl_1647
CCU: Ccur_00700
SHI: Shel_21480
ELE: Elen_1037
TPA: TP0274
TPP: TPASS_0274
TDE: TDE2193
BTH: BT_4260
BFR: BF0964
BFS: BF0882
BVU: BVU_2625
PGI: PG1856
PGN: PGN_1789
PDI: BDI_0206
CHU: CHU_2215(dcdA)
DFE: Dfer_1068
PHE: Phep_0992
GFO: GFO_3484
FJO: Fjoh_0530
FPS: FP0464
FBA: FIC_00166
COC: Coch_1376
RBI: RB2501_05825
BBL: BLBBGE_505
BPI: BPLAN_134
AAS: Aasi_1340
FSU: Fisuc_3037
FNU: FN1902
LBA: Lebu_1485
STR: Sterm_2482
SMF: Smon_0918
OTE: Oter_3632
AMU: Amuc_0340
EMI: Emin_1174
RSD: TGRD_248
TAI: Taci_1570
MAR: MAE_60660
CYT: cce_0387
CYP: PCC8801_1242
CYC: PCC7424_0712
CYH: Cyan8802_1272
TER: Tery_2084
CTE: CT0746
CPC: Cpar_0709
CCH: Cag_0622
CPH: Cpha266_0943
CPB: Cphamn1_1624
CLI: Clim_0828
PVI: Cvib_1106
PLT: Plut_0726
PPH: Ppha_1891
PAA: Paes_0827
CTS: Ctha_2080
DET: DET0413
DEH: cbdb_A365
DEB: DehaBAV1_0392
DEV: DhcVS_356(comEB)
DRA: DR_2631
DDR: Deide_23030
TMA: TM0404
TPT: Tpet_0516
TLE: Tlet_0751
TRQ: TRQ2_0530
TNA: CTN_0265
TNP: Tnap_0196
TME: Tmel_1766
TAF: THA_98
FNO: Fnod_0042
PMO: Pmob_0204
KOL: Kole_0321
MAC: MA0136 MA0137
MBA: Mbar_A0853
MMA: MM_1423
MBU: Mbur_1985
MTP: Mthe_0257
MEM: Memar_0885
MBN: Mboo_0627
MPD: MCP_0097
AFU: AF1764
TAC: Ta0312
TVO: TVN1288
PTO: PTO0422
PHO: PH1589
PAB: PAB1975
PFU: PF1598
TKO: TK2257
TON: TON_1368
TGA: TGAM_1074
TSI: TSIB_1276
RCI: RCIX305
NMR: Nmar_0947
 |
|---|
| Structures |
PDB: 1VQ2 2HVV 2HVW 2W4L |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14442222]
SCARANO E.
The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides.
I. The enzymatic deamination of deoxycytidine 5'-phosphate and of
5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate.
J. Biol. Chem. 235 (1960) 706-13.
Mus musculus [GN:mmu], Saccharomyces cerevisiae [GN:sce],
Escherichia coli [GN:eco], Oryctolagus cuniculus |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13747062]
SCARANO E, BONADUCE L, DE PETROCELLISB.
The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides.
II. Purification and properties of a 6-aminopyrimidine
deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of
sea urchine.
J. Biol. Chem. 235 (1960) 3556-61.
Sphaerechinus granularis, Paracentrotus lividus |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:5002683]
Sergott RC, Debeer LJ, Bessman MJ.
On the regulation of a bacterial deoxycytidylate deaminase.
J. Biol. Chem. 246 (1971) 7755-8.
Lactobacillus acidophilus [GN:lac] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.4.12
IUBMB Enzyme Nomenclature: 3.5.4.12
ExPASy - ENZYME nomenclature database: 3.5.4.12
BRENDA, the Enzyme Database: 3.5.4.12
CAS: 9026-92-0 |
|---|
