| Entry |
|
|---|
| Name |
1-pyrroline-4-hydroxy-2-carboxylate deaminase;
HPC deaminase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
 |
|---|
| Sysname |
1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing) |
|---|
| Reaction(IUBMB) |
1-pyrroline-4-hydroxy-2-carboxylate + H2O = 2,5-dioxopentanoate +
NH3 [RN:R02280] |
|---|
| Reaction(KEGG) |
R02280
 |
|---|
| Substrate |
1-pyrroline-4-hydroxy-2-carboxylate [CPD:C04282];
H2O [CPD:C00001] |
|---|
| Product |
2,5-dioxopentanoate [CPD:C00433];
NH3 [CPD:C00014] |
|---|
| Pathway |
PATH: ec00330 Arginine and proline metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5845838]
Singh RM, Adams E.
Enzymatic deamination of delta-1-pyrroline-4-hydroxy-2-carboxylate
to 2,5-dioxovalerate (alpha-ketoglutaric semialdehyde).
J. Biol. Chem. 240 (1965) 4344-51.
Pseudomonas striata |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:5845839]
Singh RM, Adams E.
Isolation and identification of 2,5-dioxovalerate, an intermediate
in the bacterial oxidation of hydroxyproline.
J. Biol. Chem. 240 (1965) 4352-6.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.4.22
IUBMB Enzyme Nomenclature: 3.5.4.22
ExPASy - ENZYME nomenclature database: 3.5.4.22
BRENDA, the Enzyme Database: 3.5.4.22
CAS: 9054-77-7 |
|---|
