| Entry |
|
|---|
| Name |
methenyltetrahydrofolate cyclohydrolase;
Citrovorum factor cyclodehydrase;
cyclohydrolase;
formyl-methenyl-methylenetetrahydrofolate synthetase (combined) |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
 |
|---|
| Sysname |
5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing) |
|---|
| Reaction(IUBMB) |
5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate
[RN:R01655] |
|---|
| Reaction(KEGG) |
R01655
 |
|---|
| Substrate |
5,10-methenyltetrahydrofolate [CPD:C00445];
H2O [CPD:C00001] |
|---|
| Product |
10-formyltetrahydrofolate [CPD:C00234] |
|---|
| Comment |
In eukaryotes, the enzyme occurs as a trifunctional enzyme that also
has methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) and
formate---tetrahydrofolate ligase (EC 6.3.4.3) activity. In some
prokaryotes, it occurs as a bifunctional enzyme that also has
dehydrogenase (EC 1.5.1.5) activity or formimidoyltetrahydrofolate
cyclodeaminase (EC 4.3.1.4) activity. |
|---|
| Pathway |
PATH: ec00630 Glyoxylate and dicarboxylate metabolism
PATH: ec00670 One carbon pool by folate
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00288 methylenetetrahydrofolate dehydrogenase (NADP+) /
methenyltetrahydrofolate cyclohydrolase /
formyltetrahydrofolate synthetase
KO: K01491 methylenetetrahydrofolate dehydrogenase (NADP+) /
methenyltetrahydrofolate cyclohydrolase |
|---|
| Genes |
HSA: 10797(MTHFD2) 4522(MTHFD1)
PTR: 452965(MTHFD1) 461253(MTHFD2L)
MCC: 702907 707059(MTHFD1)
MMU: 108156(Mthfd1) 17768(Mthfd2)
RNO: 313410(RGD1564040) 64300(Mthfd1) 680308(Mthfd2)
CFA: 480352(MTHFD1) 483107(MTHFD2)
BTA: 517539(MTHFD2) 534382(MTHFD1)
ECB: 100053990 100062154
MDO: 100023851 100024210 100027684
GGA: 423508(MTHFD1) 426126(RCJMB04_12b8)
TGU: 100218066 100224318 100224764
XLA: 380266(mthfd1) 446641(mthfd2)
XTR: 100170462 493369(TNeu036b14.1)
DRE: 100004977(mthfd2) 260441(mthfd1)
BFO: BRAFLDRAFT_120483 BRAFLDRAFT_62006
CIN: 100185664 100186867
SPU: 588966
DME: Dmel_CG18466(Nmdmc) Dmel_CG4067(pug)
DPO: Dpse_GA13173
DAN: Dana_GF17545 Dana_GF18431
DER: Dere_GG17628
DPE: Dper_GL11980
DSE: Dsec_GM23891 Dsec_GM26287
DSI: Dsim_GD18702 Dsim_GD20823
DYA: Dyak_GE26043
DGR: Dgri_GH14901 Dgri_GH18238
DMO: Dmoj_GI10194 Dmoj_GI23694
AGA: AgaP_AGAP002830 AgaP_AGAP004677
AAG: AaeL_AAEL006085 AaeL_AAEL014871
CQU: CpipJ_CPIJ004710
AME: 550749
NVI: 100116505
TCA: 656820
API: 100164363
CEL: K07E3.3(dao-3)
CBR: CBG16896
NVE: NEMVE_v1g158170
TAD: TRIADDRAFT_49681 TRIADDRAFT_50697
ATH: AT3G12290
POP: POPTR_552147(THF-DHG/CYH1)
RCU: RCOM_0333230 RCOM_1439680
VVI: 100249948 100255621(GSVIVT00027962001)
OSA: 4328117(Os02g0120900) 4337829(Os05g0150800)
SBI: SORBI_04g001700(SORBIDRAFT_04g001700)
SORBI_09g003920(SORBIDRAFT_09g003920)
ZMA: 100272563(pco112665)
PPP: PHYPADRAFT_129285 PHYPADRAFT_150920
CRE: CHLREDRAFT_194856
OLU: OSTLU_16077 OSTLU_27405
CME: CMR167C
SCE: YBR084W(MIS1) YGR204W(ADE3)
AGO: AGOS_ACL121C AGOS_AER178W
KLA: KLLA0E12485g KLLA0E16588g
DHA: DEHA0G24970g
PIC: PICST_80013(MIS1) PICST_88119(ADE3)
CAL: CaO19.7534(MIS1)
CGR: CAGL0K00913g CAGL0M01694g
YLI: YALI0E01056g
SPO: SPBC2G2.08(ade9) SPBC839.16
NCR: NCU03877
PAN: PODANSg944
MGR: MGG_01014
AFM: AFUA_3G08650
AOR: AO090005001405
ANG: An02g12420
AFV: AFLA_086410
PCS: Pc20g03600
NFI: NFIA_068470
CIM: CIMG_07671
SSL: SS1G_03895
CNE: CNG00590
CNB: CNBG4190
LBC: LACBIDRAFT_187631
UMA: UM03320.1
MBR: MONBRDRAFT_7587
DDI: DDB_0230115
TET: TTHERM_00339820
PTM: GSPATT00017156001 GSPATT00018560001 GSPATT00038038001
TBR: Tb927.7.1600
TCR: 508207.240 509509.20 511517.60 511741.50
LMA: LmjF26.0320 LmjF30.2600
LIF: LinJ26.0310
LBZ: LbrM26_V2.0350
PTI: PHATRDRAFT_23623
TPS: THAPSDRAFT_34399
ECO: b0529(folD)
ECJ: JW0518(folD)
ECD: ECDH10B_0485(folD)
EBW: BWG_0404(folD)
ECE: Z0684(folD)
ECS: ECs0591
ECF: ECH74115_0630(folD)
ETW: ECSP_0603(folD)
ECG: E2348C_0462(folD)
ECC: c0645(folD)
ECI: UTI89_C0559(folD)
ECP: ECP_0590
ECV: APECO1_1486(folD)
ECW: EcE24377A_0570(folD)
ECX: EcHS_A0603(folD)
ECM: EcSMS35_0574(folD)
ECY: ECSE_0554
ECL: EcolC_3093
ECK: EC55989_0543(folD)
ECQ: ECED1_0549(folD)
ECR: ECIAI1_0531(folD)
ECT: ECIAI39_0494(folD)
ECZ: ECS88_0529(folD)
EUM: ECUMN_0569(folD)
ELF: LF82_0724(folD)
EBL: B21_00484(folD)
EBD: ECBD_3129
EBR: ECB_00479(folD)
EOH: ECO103_0501(folD)
EOI: ECO111_0561(folD)
EOJ: ECO26_0562(folD)
EFE: EFER_0571(folD)
STY: STY0588(folD)
STT: t2321(folD)
SPT: SPA2183(folD)
SEK: SSPA2029
SPQ: SPAB_03022
SEI: SPC_0556(folD)
SEC: SC0581(folD)
SEH: SeHA_C0650(folD)
SEE: SNSL254_A0595(folD)
SEW: SeSA_A0587(folD)
SEA: SeAg_B0588(folD)
SED: SeD_A0590(folD)
SEG: SG0554(folD)
SET: SEN0523(folD)
SES: SARI_02412
STM: STM0542(folD)
YPE: YPO2824(folD)
YPK: y1110(folD)
YPM: YP_0855(folD)
YPA: YPA_2565
YPN: YPN_1020
YPG: YpAngola_A1281(folD)
YPP: YPDSF_2708
YPS: YPTB1037(folD)
YPI: YpsIP31758_3012(folD)
YPY: YPK_3150
YPB: YPTS_1085
YEN: YE3045(ads)
SFL: SF0460(folD)
SFX: S0468(folD)
SFV: SFV_0487(folD)
SSN: SSON_0489(folD)
SBO: SBO_0414(folD)
SBC: SbBS512_E0445(folD)
SDY: SDY_0281(folD)
ECA: ECA3149(folD)
PCT: PC1_2931
PWA: Pecwa_1347
ETA: ETA_24340(folD)
PLU: plu4317(folD)
PAY: PAU_01002(folD)
BUC: BU486(folD)
BAS: BUsg470(folD)
BAB: bbp430(folD)
BCC: BCc_305(folD)
BAP: BUAP5A_479(folD)
BAU: BUAPTUC7_480(folD)
WBR: WGLp242(folD)
SGL: SG0706
ENT: Ent638_0986
ESA: ESA_02756
CTU: Ctu_11150(folD)
KPN: KPN_00484(folD)
KPE: KPK_4195(folD)
KPU: KP1_1391(folD)
CKO: CKO_02629
SPE: Spro_1168
PMR: PMI2155(folD)
EIC: NT01EI_3003
ETR: ETAE_2695
BFL: Bfl305(folD)
BPN: BPEN_313(folD)
HDE: HDEF_1897(folD)
DDA: Dd703_2658
DDC: Dd586_2964
DZE: Dd1591_1250
HIN: HI0609(folD)
HIT: NTHI0864(folD)
HIP: CGSHiEE_02020
HIQ: CGSHiGG_06985
HDU: HD1108(folD)
HAP: HAPS_1144(folD)
HSO: HS_1221(folD)
HSM: HSM_0859
PMU: PM1933(folD)
APL: APL_0897(folD)
APJ: APJL_0909(folD)
APA: APP7_0956
ASU: Asuc_0763
AAP: NT05HA_1689
AAT: D11S_0601
XFA: XF2431
XFT: PD1449(folD)
XFM: Xfasm12_1590
XFN: XfasM23_1533
XCC: XCC2185(folD)
XCB: XC_1933
XCA: xccb100_1995
XCV: XCV2487(folD)
XAC: XAC2289(folD)
XOO: XOO2193(folD)
XOM: XOO_2061
XOP: PXO_00904(folD)
SML: Smlt2069(folD)
SMT: Smal_1669
VCH: VC1942
VCO: VC0395_A1533(folD)
VCM: VCM66_1866(folD)
VCJ: VCD_002420
VVU: VV1_2022
VVY: VV2391
VPA: VP0879
VHA: VIBHAR_01391
VSP: VS_0889
VEX: VEA_004081
VFI: VF_1770(folD)
VFM: VFMJ11_1898
VSA: VSAL_I2209(folD)
PPR: PBPRA2641
PAE: PA1796(folD)
PAU: PA14_41350(folD)
PAP: PSPA7_3507(folD)
PAG: PLES_35331(folD)
PPU: PP_1945(folD-1) PP_2265(folD-2)
PPF: Pput_3472
PPG: PputGB1_1899 PputGB1_2105
PPW: PputW619_1739
PST: PSPTO_2453(folD-1) PSPTO_3733(folD-2)
PSB: Psyr_1743 Psyr_2225
PSP: PSPPH_1687(folD1) PSPPH_2961(folD2)
PFL: PFL_3992
PFO: Pfl01_3699
PFS: PFLU2320(folD) PFLU2328 PFLU3931
PEN: PSEEN1862(folD)
PMY: Pmen_2048 Pmen_3458 Pmen_3471
PSA: PST_2054(folD)
CJA: CJA_1964(folD)
AVN: Avin_23540(folD)
PAR: Psyc_0673(folD)
PCR: Pcryo_0640
PRW: PsycPRwf_1815
ACI: ACIAD2553(folD) ACIAD2847(folD)
ACB: A1S_2674
ABM: ABSDF0803(folD)
ABY: ABAYE0812(folD)
ABC: ACICU_02919
ABN: AB57_3091
ABB: ABBFA_000800
SON: SO_1792(folD)
SDN: Sden_2497
SFR: Sfri_2598
SAZ: Sama_1222
SBL: Sbal_1602
SBM: Shew185_1591
SBN: Sbal195_1625
SBP: Sbal223_2752
SLO: Shew_2510
SPC: Sputcn32_1488
SSE: Ssed_1539
SPL: Spea_2683
SHE: Shewmr4_2497
SHM: Shewmr7_2565
SHN: Shewana3_2663
SHW: Sputw3181_2613
SHL: Shal_2770
SWD: Swoo_3115
SWP: swp_3263
ILO: IL1008(folD)
CPS: CPS_3133(folD1) CPS_3791(folD2)
PHA: PSHAa2064(folD)
PAT: Patl_3139
SDE: Sde_1920
MAQ: Maqu_1842
AMC: MADE_02962
PIN: Ping_1473
TTU: TERTU_1926(folD)
CBU: CBU_0312(folD)
CBS: COXBURSA331_A0419(folD)
CBD: CBUD_1768(folD)
CBG: CbuG_1693(folD)
CBC: CbuK_0508(folD)
LPN: lpg1297(folD)
LPF: lpl1260(folD)
LPP: lpp1261(folD)
LPC: LPC_0722(folD)
MCA: MCA0507(fchA) MCA0508
FTU: FTT_0892(folD)
FTF: FTF0892(folD)
FTW: FTW_1287(folD)
FTL: FTL_0394
FTH: FTH_0386
FTA: FTA_0417
FTM: FTM_0480(folD)
FTN: FTN_0417(folD)
FPH: Fphi_0420
TCX: Tcr_0723 Tcr_1343
NOC: Noc_2248
AEH: Mlg_0591
HHA: Hhal_0610
TGR: Tgr7_0937
HNA: Hneap_0646
HCH: HCH_02155(folD)
CSA: Csal_2048
ABO: ABO_1208(hmd)
MMW: Mmwyl1_3759
AHA: AHA_1854
ASA: ASA_2449(folD)
TAU: Tola_1915
DNO: DNO_1298(folD)
AFE: Lferr_1552
AFR: AFE_1877(folD)
BCI: BCI_0122(folD)
RMA: Rmag_0840
VOK: COSY_0765(folD)
KKO: Kkor_1959
NMA: NMA0354
NMC: NMC2056(folD)
NMN: NMCC_0107(folD)
NMI: NMO_0090(folD)
NGO: NGO1999
NGK: NGK_2241
CVI: CV_1925(folD)
LHK: LHK_01018(folD)
RSO: RSc1596(folD)
RPI: Rpic_1950
RPF: Rpic12D_1622
REU: Reut_A1299
REH: H16_A1370(folD)
RME: Rmet_1192
CTI: RALTA_A1289(folD)
BMA: BMA1724(folD)
BMV: BMASAVP1_A2234(folD)
BML: BMA10229_A3085(folD)
BMN: BMA10247_1506(folD)
BPS: BPSL2304(folD)
BPM: BURPS1710b_2749(folD)
BPL: BURPS1106A_2672(folD)
BPD: BURPS668_2616(folD)
BPR: GBP346_A2796
BTE: BTH_I1861
BVI: Bcep1808_2220
BUR: Bcep18194_A5446
BCN: Bcen_5937
BCH: Bcen2424_2140
BCM: Bcenmc03_2158
BCJ: BCAL2212(folD)
BAM: Bamb_2177
BAC: BamMC406_2050
BMU: Bmul_1130
BMJ: BMULJ_02124(folD)
BXE: Bxe_A1536
BPH: Bphy_1475 Bphy_5922
BPY: Bphyt_2595
BGL: bglu_1g24840
PNU: Pnuc_0731
PNE: Pnec_0703
BPE: BP0990(folD) BP2522(folD)
BPA: BPP1459(folD) BPP3509(folD)
BBR: BB2533(folD)
BPT: Bpet3022(folD)
BAV: BAV1660(folD)
RFR: Rfer_2209
POL: Bpro_2675
PNA: Pnap_1778
AAV: Aave_2459
AJS: Ajs_2128
VEI: Veis_1922
DAC: Daci_3983
DIA: Dtpsy_1654
VAP: Vapar_2159
CTT: CtCNB1_2244
MPT: Mpe_A2131 Mpe_A3258 Mpe_A3259
HAR: HEAR0745(folD)
MMS: mma_0672(folD)
LCH: Lcho_0175 Lcho_1643
NEU: NE0362(folD)
NET: Neut_1607
NMU: Nmul_A0357
EBA: ebA118(folD)
AZO: azo1377(folD)
DAR: Daro_0448
TBD: Tbd_0689
MFA: Mfla_0073
MMB: Mmol_0217
MEI: Msip34_0076
APP: CAP2UW1_1830
HPY: HP0577
HPJ: jhp0524(folD)
HPA: HPAG1_0556
HPS: HPSH_03990
HPG: HPG27_536
HPP: HPP12_0583(folD)
HPB: HELPY_0799(folD)
HHE: HH1366(folD)
HAC: Hac_1435(folD)
WSU: WS1345(folD)
TDN: Suden_1113
CJE: Cj0855(folD)
CJR: CJE0942(folD)
CJJ: CJJ81176_0871(folD)
CJU: C8J_0802(folD)
CJD: JJD26997_1004(folD)
CFF: CFF8240_1174
CCV: CCV52592_0799
CHA: CHAB381_1036
CCO: CCC13826_0832
CLA: Cla_0581(folD)
ABU: Abu_0637(folD)
SDL: Sdel_0845
NIS: NIS_0711(folD)
SUN: SUN_0665(folD)
NAM: NAMH_0757
GSU: GSU0215(folD-1) GSU0862(folD-2)
GME: Gmet_0247 Gmet_1162
GUR: Gura_1169
GLO: Glov_0508
GBM: Gbem_1497 Gbem_2920
GEO: Geob_1799
GEM: GM21_1305 GM21_2719
PCA: Pcar_2461(folD)
PPD: Ppro_0480
DVU: DVU0323(folD)
DVL: Dvul_2658
DVM: DvMF_1809
DDE: Dde_0296
DDS: Ddes_2215
DMA: DMR_11650(folD)
DSA: Desal_3423
LIP: LI0875
DBA: Dbac_3223
DRT: Dret_0218
BBA: Bd3295(folD)
DPS: DP1901
DOL: Dole_2033
DAL: Dalk_3403
DAT: HRM2_16710(folD)
ADE: Adeh_1247
ACP: A2cp1_2712
AFW: Anae109_2520
ANK: AnaeK_2618
MXA: MXAN_2226(folD) MXAN_3032(folD)
SCL: sce3713(folD1)
HOH: Hoch_3221
SAT: SYN_02873
SFU: Sfum_2686
RPR: RP515
RTY: RT0501(folD)
RCM: A1E_02990
RCO: RC0636(folD)
RFE: RF_0699(folD)
RAK: A1C_03455
RRI: A1G_03600
RRJ: RrIowa_0761
RMS: RMA_0646(folD)
RPK: RPR_00445
RAF: RAF_ORF0590(folD)
RBE: RBE_0983(folD)
RBO: A1I_03740
OTS: OTBS_1842(folD)
OTT: OTT_1323(folD)
WOL: WD0555(folD)
WBM: Wbm0073
WRI: WRi_003750(folD)
WPI: WPa_0744(folD)
AMA: AM179(folD)
AMF: AMF_134(folD)
ACN: ACIS_01098(folD)
APH: APH_0175(folD)
ERU: Erum6730(folD)
ERW: ERWE_CDS_07060(folD)
ERG: ERGA_CDS_06980(folD)
ECN: Ecaj_0680
ECH: ECH_0324(folD)
NSE: NSE_0821(folD)
NRI: NRI_0790
PUB: SAR11_0307(folD)
MLO: mll6921 mlr6508
MES: Meso_0152
PLA: Plav_1372
SME: SMc02604(folD1) SMc03059(folD2)
SMD: Smed_0290 Smed_2095
ATU: Atu0589(folD)
ATC: AGR_C_1042(folD)
ARA: Arad_0930(folDch) Arad_8371(folDch)
AVI: Avi_0782(folD)
RET: RHE_CH00694(folDch) RHE_PE00416(folDe)
REC: RHECIAT_CH0000772(folD1) RHECIAT_CH0002061(folD2)
RLE: RL0743
RLT: Rleg2_0353 Rleg2_1627 Rleg2_5643
RLG: Rleg_0385
RHI: NGR_b16620 NGR_c03080(folD2)
LAS: CLIBASIA_01965(folD)
BME: BMEII0510
BMI: BMEA_B0759
BMF: BAB2_0457(folD)
BMB: BruAb2_0451(folD)
BMC: BAbS19_II04320
BMS: BRA0781(folD)
BMT: BSUIS_B0773
BOV: BOV_A0731(folD)
BCS: BCAN_B0794(folD)
BMR: BMI_II774(folD)
OAN: Oant_3959
BJA: bll0549(folD)
BRA: BRADO0277(folD)
BBT: BBta_0269(folD)
RPA: RPA0413
RPB: RPB_0108
RPC: RPC_0059
RPD: RPD_0694
RPE: RPE_0047
RPT: Rpal_0417
NWI: Nwi_0480
NHA: Nham_0609
OCA: OCAR_4309
BHE: BH03940(folD)
BQU: BQ02960(folD)
BBK: BARBAKC583_0297(folD)
BTR: Btr_0602(folD)
BGR: Bgr_04240(folD)
XAU: Xaut_4086
AZC: AZC_2306
MEX: Mext_1797
MRD: Mrad2831_3668
MET: M446_6554
MPO: Mpop_1749
MCH: Mchl_2133 Mchl_5700
MNO: Mnod_7114
BID: Bind_0805
MSL: Msil_1881
CCR: CC_1217
CCS: CCNA_01275
CAK: Caul_1714
PZU: PHZ_c2033(folD)
SIL: SPO1559 SPO1560(folD) SPO3101
SIT: TM1040_2356
RSP: RSP_0661
RSH: Rsph17029_2314
RSQ: Rsph17025_0571
RSK: RSKD131_2017
JAN: Jann_0983
RDE: RD1_2105(folD) RD1_4236(folD) RD1_4237(folD)
PDE: Pden_2614 Pden_4905
DSH: Dshi_1285(folD)
MMR: Mmar10_0051
HNE: HNE_3253
HBA: Hbal_2913
ZMO: ZMO0914
ZMN: Za10_0385
NAR: Saro_3300 Saro_3791
SAL: Sala_3097
SWI: Swit_0940 Swit_2872
ELI: ELI_11530
GOX: GOX0792
GBE: GbCGDNIH1_0050 GbCGDNIH1_0051
ACR: Acry_2656
GDI: GDI_1305(folD)
GDJ: Gdia_2015
APT: APA01_02250
RRU: Rru_A0557
RCE: RC1_2876(folD)
MAG: amb4374
MGM: Mmc1_3712
BSU: BSU24310(folD)
BHA: BH2784(folD)
BAN: BA4405(folD)
BAR: GBAA4405(folD)
BAA: BA_4857
BAT: BAS4085
BAH: BAMEG_4440(folD)
BAI: BAA_4422(folD)
BCE: BC4180
BCA: BCE_4254(folD)
BCZ: BCZK3934(folD)
BCR: BCAH187_A4311(folD)
BCB: BCB4264_A4291(folD)
BCU: BCAH820_4201(folD)
BCG: BCG9842_B0943(folD)
BCQ: BCQ_3967(folD)
BCX: BCA_4290(folD)
BCY: Bcer98_2874
BTK: BT9727_3923(folD)
BTL: BALH_3789(folD)
BWE: BcerKBAB4_4033
BLI: BL01527(folD)
BLD: BLi02602(folD)
BCL: ABC3388(folD)
BAY: RBAM_022640(folD)
BPU: BPUM_2163(folD)
OIH: OB1880(folD)
GKA: GK2396
GTN: GTNG_2327
GWC: GWCH70_2324
GYM: GYMC10_2105 GYMC10_3871
GYC: GYMC61_0247
AFL: Aflv_0944(folD)
SAU: SA0915(folD)
SAV: SAV1063(folD)
SAW: SAHV_1055(folD)
SAM: MW0946(folD)
SAR: SAR1037(folD)
SAS: SAS0999
SAC: SACOL1072(folD)
SAB: SAB0930c(folD)
SAA: SAUSA300_0965(folD)
SAX: USA300HOU_1008(folD)
SAO: SAOUHSC_01007
SAJ: SaurJH9_1123
SAH: SaurJH1_1145
SAE: NWMN_0932(folD)
SAD: SAAV_1028(folD)
SEP: SE0761
SER: SERP0648(folD)
SHA: SH1894(folD)
SSP: SSP1727
SCA: Sca_0685(folD)
LMO: lmo1360(folD)
LMF: LMOf2365_1377(folD)
LMH: LMHCC_1211
LMC: Lm4b_01368(folD)
LIN: lin1397
LWE: lwe1375(folD)
LSP: Bsph_3514(folD)
ESI: Exig_0904
EAT: EAT1b_0522
MCL: MCCL_0686(folD)
BBE: BBR47_23370(folD)
PJD: Pjdr2_2308
AAC: Aaci_1777 Aaci_2840
LLA: L76582(folD)
LLK: LLKF_0872(folD)
LLC: LACR_0921
LLM: llmg_1693(folD)
SPY: SPy_1502(folD)
SPZ: M5005_Spy_1234(folD)
SPM: spyM18_1520(folD)
SPG: SpyM3_1157(folD)
SPS: SPs0705
SPH: MGAS10270_Spy1250(folD)
SPI: MGAS10750_Spy1341(folD)
SPJ: MGAS2096_Spy1252(folD)
SPK: MGAS9429_Spy1228(folD)
SPF: SpyM50619(folD)
SPA: M6_Spy1254
SPB: M28_Spy1173(folD)
SOZ: Spy49_1158c(folD)
SPN: SP_0825
SPD: SPD_0721(folD)
SPR: spr0729(folD)
SPW: SPCG_0766
SPX: SPG_0747
SNE: SPN23F_07460(folD)
SPV: SPH_0924
SNM: SP70585_0862
SJJ: SPJ_0763
SPP: SPP_0832
SNT: SPT_1376
SAG: SAG0494(folD)
SAN: gbs0540
SAK: SAK_0595(folD)
SMU: SMU.572(folD)
STC: str0611(folD)
STL: stu0611(folD)
STE: STER_0660
SSA: SSA_0671(folD)
SSU: SSU05_0497
SSV: SSU98_0490
SSB: SSUBM407_0435(folD)
SSI: SSU0448(folD)
SSS: SSUSC84_0432(folD)
SGO: SGO_0690(folD)
SEQ: SZO_13810
SEZ: Sez_0614(folD)
SEU: SEQ_0638
SUB: SUB1277(folD)
SDS: SDEG_1488
LPL: lp_1599(folD)
LPJ: JDM1_1340(folD)
LJO: LJ1215 LJ1550
LJF: FI9785_713(folD) FI9785_964(folD)
LAC: LBA1332(folD)
LSA: LSA0676(folD)
LSL: LSL_0533(folD)
LDB: Ldb1425(folD)
LBU: LBUL_1320
LBR: LVIS_0978
LCA: LSEI_1639
LCB: LCABL_18550(folD)
LGA: LGAS_0751
LRE: Lreu_1184
LRF: LAR_1116
LHE: lhv_1415
LFE: LAF_1263
LRH: LGG_01683(folD)
LRL: LC705_01664(folD)
PPE: PEPE_0817
EFA: EF0978(folD)
OOE: OEOE_0943
LME: LEUM_0460
LCI: LCK_01322(folD)
CAC: CAC2083(folD)
CPE: CPE1823(folD)
CPF: CPF_2077(folD)
CPR: CPR_1791(folD)
CTC: CTC01579
CTH: Cthe_1093
CDF: CD0719(fchA) CD0720(folD)
CDC: CD196_0665(folD)
CDL: CDR20291_0647(folD)
CBO: CBO1171(fchA) CBO1172
CBA: CLB_1202(fchA) CLB_1203(folD)
CBH: CLC_1214(fchA) CLC_1215(folD)
CBY: CLM_1322 CLM_1323(folD)
CBL: CLK_0606(fchA) CLK_0607(folD)
CBK: CLL_A2405
CBB: CLD_3397(folD) CLD_3398(fchA)
CBI: CLJ_B1212 CLJ_B1213(folD)
CBT: CLH_2170
CBF: CLI_1253(fchA) CLI_1254(folD)
CBE: Cbei_1702
CKL: CKL_0441(fchA) CKL_0442(folD)
CKR: CKR_0387
CPY: Cphy_2456
CCE: Ccel_0604
AMT: Amet_2019 Amet_2020
AOE: Clos_0249
STH: STH1847
SWO: Swol_1474
VPR: Vpar_1519
ATE: Athe_0982
DSY: DSY0606 DSY0607 DSY2356
DHD: Dhaf_0557 Dhaf_3496
DRM: Dred_1073
DAE: Dtox_2589
PTH: PTH_1183(folD) PTH_1184
DAU: Daud_0103 Daud_1022
HMO: HM1_1888(folD)
FMA: FMG_0575
APR: Apre_1131
EEL: EUBELI_00434 EUBELI_00435
ERE: EUBREC_1957
TTE: TTE1293(folD)
TEX: Teth514_1535
TPD: Teth39_1098
CHY: CHY_0696(fchA1) CHY_1878(folD) CHY_1879(fchA2)
MTA: Moth_1516
ADG: Adeg_1278
CSC: Csac_2142
CPO: COPRO5265_1066
NTH: Nther_1700
HOR: Hore_06480
MGE: MG_013(folD)
MPU: MYPU_2580(folD)
MPE: MYPE6880(folD)
MGA: MGA_0596(folD)
MMY: MSC_0758(folD)
MMO: MMOB1600(folD)
MSY: MS53_0297(folD)
MCP: MCAP_0706(folD)
MAA: MAG_1380(folD)
MAT: MARTH_orf383(folD)
MHO: MHO_1920(folD)
UUR: UU337(folD)
UPA: UPA3_0353
UUE: UUR10_0344
ACL: ACL_0033(folD)
MFL: Mfl167
MTU: Rv3356c(folD)
MTC: MT3464(folD)
MRA: MRA_3396(folD)
MTF: TBFG_13392
MTB: TBMG_03407(TBMG_03407.1)
MBO: Mb3391c(folD)
MBB: BCG_3428c(folD)
MBT: JTY_3428(folD)
MLE: ML0674(folD)
MLB: MLBr_00674(folD)
MPA: MAP3463c(folD)
MAV: MAV_4323
MSM: MSMEG_1647
MUL: MUL_1428(folD)
MVA: Mvan_1550
MGI: Mflv_4879
MAB: MAB_3692c
MMC: Mmcs_1204
MKM: Mkms_1221
MJL: Mjls_1231
MMI: MMAR_1176(folD)
CGL: NCgl0620(cgl0648)
CGB: cg0750(folD)
CGT: cgR_0763
CEF: CE0659
CDI: DIP0620(folD)
CJK: jk1697
CUR: cur_0420(folD)
CAR: cauri_0510(folD)
CKP: ckrop_1579(folD)
NFA: nfa34300(folD)
RHA: RHA1_ro01817 RHA1_ro06234(folD)
RER: RER_19980(folD) RER_33430(folD)
ROP: ROP_14940(folD) ROP_62930(folD)
GBR: Gbro_1757
SCO: SCO4824(folD)
SMA: SAV_3442(folD1) SAV_543(folD2)
SGR: SGR_2714
TWH: TWT634(folD)
TWS: TW653(folD)
LXX: Lxx18630(folD)
CMI: CMM_2521(folD)
CMS: CMS_0585
ART: Arth_1116
AAU: AAur_0482(folD) AAur_1228
ACH: Achl_1190 Achl_3465
RSA: RSal33209_0272
KRH: KRH_17990(folD)
MLU: Mlut_04690
BCV: Bcav_2988
BFA: Bfae_21360
JDE: Jden_0695
KSE: Ksed_07820
XCE: Xcel_0755
PAC: PPA1743
NCA: Noca_0641 Noca_3582
TFU: Tfu_2571
TCU: Tcur_4213
SRO: Sros_0348 Sros_1250
FRA: Francci3_1492 Francci3_2667
FRE: Franean1_4183
FAL: FRAAL2298(folD) FRAAL4216(folD)
ACE: Acel_0385
NML: Namu_1278
KRA: Krad_3980
SEN: SACE_4498(folD) SACE_6651(folD)
SVI: Svir_05000 Svir_11680
AMI: Amir_4015 Amir_6498
STP: Strop_2276 Strop_3795
SAQ: Sare_0067 Sare_4175
CAI: Caci_7979 Caci_8052
BLO: BL0993(folD)
BLJ: BLD_0746(folD)
BLN: Blon_1755
BAD: BAD_0673(folD)
BLA: BLA_1499(folD)
BLC: Balac_0989
BLT: Balat_0989
RXY: Rxyl_0827 Rxyl_1566 Rxyl_2517
AFO: Afer_0323
CCU: Ccur_00190
SHI: Shel_20930 Shel_24890
APV: Apar_0623
ELE: Elen_2861
CTR: CT078(folD)
CTA: CTA_0083(folD)
CTB: CTL0334(folD)
CTL: CTLon_0329(folD)
CTJ: JALI_0771(folD)
CMU: TC0350(folD)
CPN: CPn0335(folD)
CPA: CP0423
CPJ: CPj0335(folD)
CPT: CpB0344
CCA: CCA00448(folD)
CAB: CAB434
CFE: CF0559(folD)
PCU: pc1701(folD)
BBU: BB0026
BBZ: BbuZS7_0026
BGA: BG0026(folD)
BAF: BAPKO_0025(folD)
BTU: BT0026
BHR: BH0026
BDU: BDU_31(folD)
BRE: BRE_30(folD)
TPA: TP0732
TPP: TPASS_0732(folD)
TDE: TDE0013(folD)
LIL: LA1865(folD)
LIC: LIC12026(folD)
LBJ: LBJ_1651(folD)
LBL: LBL_1870(folD)
LBI: LEPBI_I1723(folD)
LBF: LBF_1670(folD)
BHY: BHWA1_01765(folD)
ABA: Acid345_4424
ACA: ACP_3313(folD)
SUS: Acid_4780
BTH: BT_1607
BFR: BF3219
BFS: BF3058
BVU: BVU_2215
PGI: PG1116(folD)
PGN: PGN_1206
PDI: BDI_0219
APS: CFPG_618
SRU: SRU_1839
RMR: Rmar_0952
CHU: CHU_1716(folD)
DFE: Dfer_1212
CPI: Cpin_6931
PHE: Phep_2069
GFO: GFO_2795(folD)
FJO: Fjoh_0243
FPS: FP1475(folD)
FBA: FIC_00126
COC: Coch_1786
RBI: RB2501_10080
BBL: BLBBGE_442(folD)
BPI: BPLAN_198(folD)
AAS: Aasi_0928
FSU: Fisuc_1501
FNU: FN1488
LBA: Lebu_0169
STR: Sterm_1178
SMF: Smon_0375
OTE: Oter_3793
MIN: Minf_0806(folD)
AMU: Amuc_1641
GAU: GAU_1870(folD)
RBA: RB10295(mtdA) RB7468(folD)
EMI: Emin_0264
RSD: TGRD_023
TAI: Taci_1086
SYN: sll0753(folD)
SYW: SYNW0740(folD)
SYC: syc0759_d(folD)
SYF: Synpcc7942_0777
SYD: Syncc9605_1928
SYE: Syncc9902_0737
SYG: sync_0990
SYR: SynRCC307_0749(folD)
SYX: SynWH7803_1570(folD)
SYP: SYNPCC7002_A0889(folD)
CYA: CYA_1974(folD)
CYB: CYB_0090(folD)
TEL: tll0021(folD)
MAR: MAE_46740(folD)
CYT: cce_0811(folD)
CYP: PCC8801_1592
CYC: PCC7424_0607
CYN: Cyan7425_0973
CYH: Cyan8802_1617
GVI: gll1884
ANA: alr0212
NPU: Npun_F3769
AVA: Ava_2703 Ava_C0058
PMA: Pro1130(folD)
PMM: PMM1069(folD)
PMT: PMT1110(folD)
PMN: PMN2A_0682
PMI: PMT9312_1080
PMB: A9601_11741(folD)
PMC: P9515_11591(folD)
PMF: P9303_09321(folD)
PMG: P9301_11751(folD)
PMH: P9215_12041(folD)
PMJ: P9211_11201(folD)
PME: NATL1_15161(folD)
TER: Tery_4172
AMR: AM1_4855(folD)
CTE: CT0719(mtd)
CPC: Cpar_0686
CCH: Cag_0779
CPH: Cpha266_0997
CPB: Cphamn1_1442
CLI: Clim_1112
PVI: Cvib_0963
PLT: Plut_0927
PPH: Ppha_1205
PAA: Paes_1178
CTS: Ctha_0449
DET: DET0668(folD-1) DET0702(folD-2)
DEH: cbdb_A656(folD)
DEB: DehaBAV1_0637
DEV: DhcVS_606(folD)
RRS: RoseRS_4392
RCA: Rcas_0735
CAU: Caur_3281
CAG: Cagg_0060
CHL: Chy400_3541
HAU: Haur_4471
TRO: trd_0733
STI: Sthe_1304
DRA: DR_0867
DGE: Dgeo_0514 Dgeo_0699
DDR: Deide_12261 Deide_16010(folD)
TTH: TTC0755
TTJ: TTHA1120
AAE: aq_1898(folD)
HYA: HY04AAS1_0893
SUL: SYO3AOP1_1067
SAF: SULAZ_0428
PMX: PERMA_1712
TMA: TM1767
TPT: Tpet_1055
TLE: Tlet_1514
TRQ: TRQ2_1057
TNA: CTN_0957
TNP: Tnap_1047
TME: Tmel_1907
TAF: THA_201
FNO: Fnod_1338
PMO: Pmob_1757
KOL: Kole_2113
DTH: DICTH_0536 DICTH_1526
DTU: Dtur_1636
TYE: THEYE_A0674
TTR: Tter_1064
MAC: MA3519(folD)
MBA: Mbar_A2315
MMA: MM_0441
MBU: Mbur_1814
MTP: Mthe_1242
MHU: Mhun_0022
MEM: Memar_1834
MBN: Mboo_2188
MPL: Mpal_0744
HAL: VNG1416G(folD)
HSL: OE3038F(folD)
HMA: pNG7328(folD2) rrnAC0996(folD1)
HWA: HQ2790A(folD)
NPH: NP2054A(folD)
HLA: Hlac_1624
HUT: Huta_2943
HMU: Hmuk_2214
TAC: Ta0898
TVO: TVN1018
PTO: PTO1071
PAI: PAE0220
PIS: Pisl_0104
PCL: Pcal_1897
PAS: Pars_2192
TNE: Tneu_1909
NMR: Nmar_1117
 |
|---|
| Structures |
PDB: 1A4I 1DIA 1DIB 1DIG 2C2X 2C2Y 3L07 |
|---|
Reference
Authors
Title
Journal
|
1
Rabinowitz, J.C. and Pricer, W.E.
The enzymatic synthesis of N10-formyltetrahydrofolic acid and its
role in ATP formation during formiminoglycine degradation.
J. Am. Chem. Soc. 78 (1956) 4176-4178. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13672973]
TABOR H, WYNGARDEN L.
The enzymatic formation of formiminotetrahydrofolic acid,
5,10-methenyltetrahydrofolic acid, and 10-formyltetrahydrofolic acid
in the metabolism of formiminoglutamic acid.
J. Biol. Chem. 234 (1959) 1830-46.
Clostridium cylindrosporum, Clostridium acidi-urici |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.4.9
IUBMB Enzyme Nomenclature: 3.5.4.9
ExPASy - ENZYME nomenclature database: 3.5.4.9
BRENDA, the Enzyme Database: 3.5.4.9
CAS: 9027-97-8 |
|---|
