KEGG   ENZYME: 3.6.1.14Help
Entry
EC 3.6.1.14                 Enzyme                                 

Name
adenosine-tetraphosphatase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
BRITE hierarchy
Sysname
adenosine-tetraphosphate phosphohydrolase
Reaction(IUBMB)
adenosine 5'-tetraphosphate + H2O = ATP + phosphate [RN:R00128]
Reaction(KEGG)
R00128;
(other) R00723
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Substrate
adenosine 5'-tetraphosphate [CPD:C03483];
H2O [CPD:C00001]
Product
ATP [CPD:C00002];
phosphate [CPD:C00009]
Comment
Also acts on inosine tetraphosphate and tripolyphosphate but shows little or no activity with other nucleotides or polyphosphates.
History
EC 3.6.1.14 created 1972
Pathway
Purine metabolism
Reference
1  [PMID:4287215]
  Authors
Small GD, Cooper C.
  Title
Purification and properties of nucleoside tetraphosphate hydrolase from rabbit muscle.
  Journal
Biochemistry. 5 (1966) 14-26.
  Organism
Oryctolagus cuniculus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37289-26-2

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