| Entry |
|
|---|
| Name |
FAD diphosphatase;
FAD pyrophosphatase;
riboflavin adenine dinucleotide pyrophosphatase;
flavin adenine dinucleotide pyrophosphatase;
riboflavine adenine dinucleotide pyrophosphatase;
flavine adenine dinucleotide pyrophosphatase |
|---|
| Class |
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
 |
|---|
| Sysname |
FAD nucleotidohydrolase |
|---|
| Reaction(IUBMB) |
FAD + H2O = AMP + FMN [RN:R00160] |
|---|
| Reaction(KEGG) |
R00160
 |
|---|
| Substrate |
FAD [CPD:C00016];
H2O [CPD:C00001] |
|---|
| Product |
AMP [CPD:C00020];
FMN [CPD:C00061] |
|---|
| Comment |
The plant enzyme also hydrolyses NAD+ and NADH; the animal enzyme
hydrolyses NAD+ and CoA at about half of the rate of hydrolysis of
FAD. May be identical with EC 3.6.1.9 nucleotide diphosphatase. |
|---|
| Pathway |
PATH: ec00740 Riboflavin metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5810832]
Ravindranath SD, Rao NA.
Nucleotidases in plants. 3. Effect of metabolites on the enzyme
hydrolyzing flavine adenine dinucleotide (FAD) from Phaseolus
radiatus.
Arch. Biochem. Biophys. 133 (1969) 54-9.
Phaseolus radiatus |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:2848456]
Shin HJ, Mego JL.
A rat liver lysosomal membrane flavin-adenine dinucleotide
phosphohydrolase: purification and characterization.
Arch. Biochem. Biophys. 267 (1988) 95-103.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.6.1.18
IUBMB Enzyme Nomenclature: 3.6.1.18
ExPASy - ENZYME nomenclature database: 3.6.1.18
BRENDA, the Enzyme Database: 3.6.1.18
CAS: 37289-30-8 |
|---|
