| Entry |
|
|---|
| Name |
thiamine-triphosphatase |
|---|
| Class |
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
 |
|---|
| Sysname |
thiamine-triphosphate phosphohydrolase |
|---|
| Reaction(IUBMB) |
thiamine triphosphate + H2O = thiamine diphosphate + phosphate
[RN:R00618] |
|---|
| Reaction(KEGG) |
R00618
 |
|---|
| Substrate |
thiamine triphosphate [CPD:C03028];
H2O [CPD:C00001] |
|---|
| Product |
thiamine diphosphate [CPD:C00068];
phosphate [CPD:C00009] |
|---|
| Pathway |
PATH: ec00730 Thiamine metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K05307 thiamine-triphosphatase |
|---|
| Genes |
HSA: 79178(THTPA)
MCC: 714403
MMU: 105663(Thtpa)
RNO: 305889(Thtpa)
CFA: 490614(THTPA)
BTA: 282090(THTPA)
SSC: 396635
ECB: 100052214
MDO: 100030627
XLA: 734744
XTR: 100037895
DRE: 100048920(thtpa)
SPU: 755966
CME: CMI051C
 |
|---|
| Structures |
PDB: 2JMU 3BHD |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4335862]
Hashitani Y, Cooper JR.
The partial purification of thiamine triphosphatase from rat brain.
J. Biol. Chem. 247 (1972) 2117-9.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.6.1.28
IUBMB Enzyme Nomenclature: 3.6.1.28
ExPASy - ENZYME nomenclature database: 3.6.1.28
BRENDA, the Enzyme Database: 3.6.1.28
CAS: 9068-47-7 |
|---|
