KEGG   ENZYME: 4.1.1.11Help
Entry
EC 4.1.1.11                 Enzyme                                 
Name aspartate 1-decarboxylase;
aspartate alpha-decarboxylase;
L-aspartate alpha-decarboxylase;
aspartic alpha-decarboxylase;
L-aspartate 1-carboxy-lyase
Class Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname L-aspartate 1-carboxy-lyase (beta-alanine-forming)
Reaction(IUBMB) L-aspartate = beta-alanine + CO2 [RN:R00489]
Reaction(KEGG) R00489
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Substrate L-aspartate [CPD:C00049]
Product beta-alanine [CPD:C00099];
CO2 [CPD:C00011]
Comment The Escherichia coli enzyme contains a pyruvoyl group.
Pathway PATH: ec00410  beta-Alanine metabolism
PATH: ec00770  Pantothenate and CoA biosynthesis
PATH: ec01100  Metabolic pathways
Orthology KO: K01579  aspartate 1-decarboxylase
Genes ECO: b0131(panD)
ECJ: JW0127(panD)
ECD: ECDH10B_0111(panD)
EBW: BWG_0124(panD)
ECE: Z0142(panD)
ECS: ECs0135
ECF: ECH74115_0139(panD)
ETW: ECSP_0132(panD)
ECG: E2348C_0134(panD)
ECC: c0160(panD)
ECI: UTI89_C0144(panD)
ECP: ECP_0139
ECV: APECO1_1854
ECW: EcE24377A_0133(panD)
ECX: EcHS_A0135(panD)
ECM: EcSMS35_0141(panD)
ECY: ECSE_0131
ECL: EcolC_3528
ECK: EC55989_0125(panD)
ECQ: ECED1_0136(panD)
ECR: ECIAI1_0129(panD)
ECT: ECIAI39_0131(panD)
ECZ: ECS88_0141(panD)
EUM: ECUMN_0129(panD)
ELF: LF82_1594(panD)
EBL: B21_00129(panD)
EBD: ECBD_3488
EBR: ECB_00130(panD)
EOH: ECO103_0131(panD)
EOI: ECO111_0132(panD)
EOJ: ECO26_0133(panD)
EFE: EFER_0152(panD)
STY: STY0198(panD)
STT: t0181(panD)
SPT: SPA0186(panD)
SEK: SSPA0182
SPQ: SPAB_00222
SEI: SPC_0194(panD)
SEC: SC0180(panD)
SEH: SeHA_C0212(panD)
SEE: SNSL254_A0197(panD)
SEW: SeSA_A0200(panD)
SEA: SeAg_B0214(panD)
SED: SeD_A0196(panD)
SEG: SG0184(panD)
SET: SEN0185(panD)
SES: SARI_02818
STM: STM0180(panD)
YPE: YPO3403(panD)
YPK: y0784(panD)
YPM: YP_0282(panD)
YPA: YPA_2904
YPN: YPN_0686
YPG: YpAngola_A1013(panD)
YPP: YPDSF_2953
YPS: YPTB0728(panD)
YPI: YpsIP31758_3345(panD)
YPY: YPK_3474
YPB: YPTS_0759
YEN: YE0718(panD)
SFL: SF0128(panD)
SFX: S0130(panD)
SFV: SFV_0121(panD)
SSN: SSON_0139(panD)
SBO: SBO_0120(panD)
SBC: SbBS512_E0124(panD)
SDY: SDY_0041(panD)
ECA: ECA3323(panD)
PCT: PC1_3120
PWA: Pecwa_1158
ETA: ETA_08550(panD)
PLU: plu0870(panD)
PAY: PAU_00804(panD)
SGL: SG0486
ENT: Ent638_0679
ESA: ESA_03202
CTU: Ctu_07700(panD)
KPN: KPN_00139(panD)
KPE: KPK_4597(panD)
KPU: KP1_0966(panD)
CKO: CKO_03230
SPE: Spro_3993
PMR: PMI0194(panD)
EIC: NT01EI_0784
ETR: ETAE_0685(panD)
DDA: Dd703_2825
DDC: Dd586_3144
DZE: Dd1591_1026
XFA: XF0231
XFT: PD0189(panD)
XFM: Xfasm12_0199
XFN: XfasM23_0175
XCC: XCC1770(panD)
XCB: XC_2466
XCA: xccb100_2493
XCV: XCV1818(panD)
XAC: XAC1787(panD)
XOO: XOO2361(panD)
XOM: XOO_2243
XOP: PXO_00688(panD)
SML: Smlt1782(panD)
SMT: Smal_1520
PAE: PA4731(panD)
PAU: PA14_62600(panD)
PAP: PSPA7_5448(panD)
PAG: PLES_51161(panD)
PFL: PFL_5279
PSA: PST_3298
CJA: CJA_2974(panD)
AVN: Avin_42730(panD)
PAR: Psyc_0169(panD)
PCR: Pcryo_0182
PRW: PsycPRwf_2108
ACI: ACIAD2911(panD)
ACB: A1S_0825
ABM: ABSDF2630(panD)
ABY: ABAYE2984(panD)
ABC: ACICU_00784
ABN: AB57_0879(panD)
ABB: ABBFA_002786(panD)
SDE: Sde_1062
PIN: Ping_0578
TTU: TERTU_0556(panD)
CBU: CBU_0422(panD)
CBS: COXBURSA331_A0529(panD)
CBD: CBUD_1651(panD)
CBG: CbuG_1590(panD)
CBC: CbuK_1646(panD)
LPN: lpg2929(panD)
LPF: lpl2856(panD)
LPP: lpp2996(panD)
LPC: LPC_3234(panD)
MCA: MCA2316(panD)
FTU: FTT_1391(panD)
FTF: FTF1391(panD)
FTW: FTW_0497(panD)
FTL: FTL_0672
FTH: FTH_0675(panD)
FTA: FTA_0707(panD)
FTM: FTM_0633(panD)
FTN: FTN_1354(panD)
FPH: Fphi_1334
TCX: Tcr_1522
NOC: Noc_0887
AEH: Mlg_0566
HHA: Hhal_0673
TGR: Tgr7_0877
CSA: Csal_3067
ABO: ABO_0335(panD)
MMW: Mmwyl1_1263
TAU: Tola_2304
AFE: Lferr_2688
AFR: AFE_3089(panD)
RMA: Rmag_0846
VOK: COSY_0771(panD)
NMA: NMA1492(panD)
NME: NMB1282(panD)
NMC: NMC1216(panD)
NMN: NMCC_1195(panD)
NMI: NMO_1125(panD)
NGO: NGO0620
NGK: NGK_1295
CVI: CV_1637(panD)
LHK: LHK_01400(panD)
RSO: RSc2731(panD)
RPI: Rpic_2970
RPF: Rpic12D_2560
REH: H16_A3129(panD)
CTI: RALTA_A2605(panD)
BMA: BMA0700(panD)
BMV: BMASAVP1_A2313(panD)
BML: BMA10229_A2974(panD)
BMN: BMA10247_1625(panD)
BPS: BPSL0990(panD)
BPM: BURPS1710b_1203(panD)
BPL: BURPS1106A_1048(panD)
BPD: BURPS668_1042(panD)
BPR: GBP346_A1041(panD)
BTE: BTH_I0847(panD)
BVI: Bcep1808_2527
BUR: Bcep18194_A5774
BCN: Bcen_1832
BCH: Bcen2424_2443
BCM: Bcenmc03_2448
BCJ: BCAL2652(panD)
BAM: Bamb_2490
BAC: BamMC406_2358
BMU: Bmul_0851
BMJ: BMULJ_02407(panD)
BXE: Bxe_A3489
BPH: Bphy_2198
BPY: Bphyt_1009
BGL: bglu_1g28090
PNU: Pnuc_0652
BPE: BP1816(panD)
BPA: BPP1899(panD)
BBR: BB3211(panD)
BAV: BAV2368(panD)
RFR: Rfer_3032
POL: Bpro_0901 Bpro_1578
PNA: Pnap_0936
AJS: Ajs_3494
DAC: Daci_1835
DIA: Dtpsy_2817
VAP: Vapar_2075 Vapar_6002
CTT: CtCNB1_3866
MPT: Mpe_A3569
HAR: HEAR0328(panD)
MMS: mma_0375(panD)
LCH: Lcho_2657
DAR: Daro_3187
TBD: Tbd_2055
MFA: Mfla_0594
MMB: Mmol_1888
MEI: Msip34_2173
APP: CAP2UW1_2450
HPY: HP0034
HPJ: jhp0030(panD)
HPA: HPAG1_0032
HPS: HPSH_00170
HPG: HPG27_31
HPP: HPP12_0030(panD)
HPB: HELPY_0032(panD)
HHE: HH0331(panD)
HAC: Hac_0047(panD)
WSU: WS1682(panD)
TDN: Suden_0334
CJE: Cj0296c(panD)
CJR: CJE0341(panD)
CJJ: CJJ81176_0319(panD)
CJU: C8J_0273(panD)
CJD: JJD26997_1668(panD)
CFF: CFF8240_0064(panD)
CCV: CCV52592_0074(panD)
CHA: CHAB381_0199(panD)
CCO: CCC13826_1739(panD)
ABU: Abu_0428(panD)
SDL: Sdel_1937
NIS: NIS_0255(panD)
SUN: SUN_2279(panD)
NAM: NAMH_1689(panD)
GUR: Gura_2080
GBM: Gbem_3010
GEM: GM21_1240
PCA: Pcar_1828(panD)
PPD: Ppro_3533
DDS: Ddes_0982
DSA: Desal_2246
DBA: Dbac_1682
DRT: Dret_1013
BBA: Bd3565(panD)
DPS: DP1942
ADE: Adeh_4051
ACP: A2cp1_4194
AFW: Anae109_0377
ANK: AnaeK_4167
MXA: MXAN_6830(panD)
SCL: sce0938(panD)
SAT: SYN_00419
SFU: Sfum_0368
MLO: mll5826 mll9093
ATU: Atu3667(panD)
ATC: AGR_L_2336
RHI: NGR_b12520(panD)
BJA: blr2096(panD)
XAU: Xaut_2340
MNO: Mnod_5641
BID: Bind_0514
MSL: Msil_1022
CCR: CC_2295
CCS: CCNA_02380
CAK: Caul_3536
PZU: PHZ_c2569(panD)
MMR: Mmar10_2123
HNE: HNE_1379(panD)
HBA: Hbal_2185
RRU: Rru_A0191
RCE: RC1_2273(panD)
MAG: amb4022
BSU: BSU22410(panD)
BHA: BH1689(panD)
BAN: BA1564(panD)
BAR: GBAA1564(panD)
BAA: BA_2083
BAT: BAS1451
BAH: BAMEG_3031(panD)
BAI: BAA_1631(panD)
BCE: BC1542
BCA: BCE_1670(panD)
BCZ: BCZK1424(panD)
BCR: BCAH187_A1708(panD)
BCB: BCB4264_A1597(panD)
BCU: BCAH820_1635(panD)
BCG: BCG9842_B3748(panD)
BCQ: BCQ_1610(panD)
BCX: BCA_1600(panD)
BCY: Bcer98_1264
BTK: BT9727_1423(panD)
BTL: BALH_1394
BWE: BcerKBAB4_1466
BLI: BL02750(panD)
BLD: BLi02376(panD)
BCL: ABC2065(panD)
BAY: RBAM_020560(panD)
BPU: BPUM_1972(panD)
OIH: OB1763(panD)
GKA: GK2177(panD)
GTN: GTNG_2111
GWC: GWCH70_2116
GYM: GYMC10_2240
GYC: GYMC61_0503
AFL: Aflv_1128(panD)
SAU: SA2390(panD)
SAV: SAV2597(panD)
SAW: SAHV_2581(panD)
SAM: MW2516(panD)
SAR: SAR2675(panD)
SAS: SAS2482
SAC: SACOL2613(panD)
SAB: SAB2470c(panD)
SAA: SAUSA300_2532(panD)
SAX: USA300HOU_2591(panD)
SAO: SAOUHSC_02916
SAJ: SaurJH9_2619
SAH: SaurJH1_2673
SAE: NWMN_2494(panD)
SAD: SAAV_2663
SEP: SE2139
SER: SERP2150(panD)
SHA: SH0183(panD)
SSP: SSP0933
SCA: Sca_2074(panD)
LMO: lmo1900(panD)
LMF: LMOf2365_1929(panD)
LMH: LMHCC_0657(panD)
LMC: Lm4b_01917(panD)
LIN: lin2014
LWE: lwe1919(panD)
LSP: Bsph_1989
ESI: Exig_1778
EAT: EAT1b_3017
BBE: BBR47_25040(panD) BBR47_30880(panD)
PJD: Pjdr2_2447
AAC: Aaci_0298 Aaci_1959
LPL: lp_0579(panD)
EFA: EF1858(panD)
CAC: CAC2916(panD)
CNO: NT01CX_1073(panD)
CTH: Cthe_0900
CBO: CBO0423(panD)
CBA: CLB_0456(panD)
CBH: CLC_0489(panD)
CBY: CLM_0370(panD) CLM_0503(panD)
CBL: CLK_3625(panD)
CBB: CLD_0320(panD)
CBI: CLJ_B0492(panD)
CBT: CLH_1682(panD)
CBF: CLI_0508(panD)
CBE: Cbei_2608
CKL: CKL_1623(panD)
CKR: CKR_1508
CCE: Ccel_1785
SWO: Swol_0103
VPR: Vpar_0931
ATE: Athe_1979
DSY: DSY0212
DHD: Dhaf_0156
DRM: Dred_0162 Dred_1790
DAE: Dtox_0242
PTH: PTH_0222(panD)
DAU: Daud_0102
HMO: HM1_0667(panD)
APR: Apre_0118
ERE: EUBREC_2499
TEX: Teth514_0425
TPD: Teth39_1810
CHY: CHY_2375(panD)
MTA: Moth_0142
ADG: Adeg_1875
CSC: Csac_2708
CPO: COPRO5265_0604(panD)
MTU: Rv3601c(panD)
MTC: MT3706.1(panD)
MRA: MRA_3640(panD)
MTF: TBFG_13633
MTB: TBMG_03639(TBMG_03639.1)
MBO: Mb3631c(panD)
MBB: BCG_3665c(panD)
MBT: JTY_3666(panD)
MLE: ML0231(panD)
MLB: MLBr_00231(panD)
MPA: MAP0457(panD)
MAV: MAV_0552(panD)
MSM: MSMEG_0021(panD)
MUL: MUL_4183(panD)
MVA: Mvan_5363
MGI: Mflv_1425
MAB: MAB_0542
MMC: Mmcs_4761
MKM: Mkms_4847
MJL: Mjls_5147
MMI: MMAR_0693(panD_1) MMAR_3177(panD_2) MMAR_5104(panD)
CGL: NCgl0133(cgl0135)
CGB: cg0172(panD)
CGT: cgR_0214
CEF: CE0135(panD)
CJK: jk0292(panD)
CUR: cur_1692
NFA: nfa4070(panD)
RHA: RHA1_ro04416
RER: RER_06340(panD)
ROP: ROP_43320(panD)
GBR: Gbro_4006
SCO: SCO0978(panD)
SMA: SAV_7245(panD)
SGR: SGR_775
CMI: CMM_0532(panD)
CMS: CMS_0449
ART: Arth_3887
AAU: AAur_3720(panD) AAur_pTC20125(panD)
ACH: Achl_3676
RSA: RSal33209_2226
KRH: KRH_03780(panD)
MLU: Mlut_20270
BFA: Bfae_12570
JDE: Jden_2095
XCE: Xcel_1645
NCA: Noca_0461
TFU: Tfu_1862
TCU: Tcur_0364 Tcur_4486
SRO: Sros_9159
FRA: Francci3_1112 Francci3_4376
FRE: Franean1_0199
FAL: FRAAL6671(panD)
ACE: Acel_0212
NML: Namu_4391
SEN: SACE_0407(panD)
SVI: Svir_35540
AMI: Amir_0326
STP: Strop_4282
SAQ: Sare_4717
CAI: Caci_8382
ELE: Elen_3013
LIL: LA1729(panD)
LIC: LIC12074(panD)
LBJ: LBJ_1234(panD)
LBL: LBL_1285(panD)
LBI: LEPBI_I2296(panD)
LBF: LBF_2227(panD)
BHY: BHWA1_01024
BTH: BT_4309
BFR: BF1004
BFS: BF0925(panD)
BVU: BVU_2899
PGI: PG1114(panD)
PGN: PGN_1204
PDI: BDI_0214
APS: CFPG_155
SRU: SRU_1412(panD)
RMR: Rmar_0750
CHU: CHU_3834(panD)
DFE: Dfer_4555
CPI: Cpin_3688
PHE: Phep_0135
GFO: GFO_3543(panD)
FJO: Fjoh_0826
FPS: FP0107(panD)
FBA: FIC_00707
COC: Coch_0106
RBI: RB2501_07965
FSU: Fisuc_0456
AMU: Amuc_0747
RBA: RB6090(panD)
RSD: TGRD_509
TAI: Taci_0465
SYN: sll0892(panD)
SYP: SYNPCC7002_A2530(panD)
MAR: MAE_37200(panD)
CYT: cce_0940(panD)
CYP: PCC8801_1838
CYC: PCC7424_4323
CYH: Cyan8802_1864
GVI: glr2845 glr4228
ANA: all3569
NPU: Npun_F2554
AVA: Ava_3547
TER: Tery_0692
AMR: AM1_2358(panD)
CTE: CT0252(panD)
CPC: Cpar_1782
CCH: Cag_1450
CPH: Cpha266_0379
CPB: Cphamn1_0412
CLI: Clim_0310
PVI: Cvib_1551
PLT: Plut_1769
PPH: Ppha_0408
PAA: Paes_0379
CTS: Ctha_1794
DET: DET0802(panD)
DEH: cbdb_A780(panD)
DEB: DehaBAV1_0726
DEV: DhcVS_706
HAU: Haur_0386
DRA: DR_0718
DGE: Dgeo_1422
DDR: Deide_08220
TTH: TTC0241
TTJ: TTHA0606
AAE: aq_476(panD)
HYA: HY04AAS1_0774
SUL: SYO3AOP1_0410
SAF: SULAZ_1371(panD)
PMX: PERMA_1512(panD)
TMA: TM0939
TPT: Tpet_1803
TLE: Tlet_0872
TRQ: TRQ2_1841
TNA: CTN_1637
TNP: Tnap_1805
TME: Tmel_0284
TAF: THA_577(panD)
FNO: Fnod_0880
KOL: Kole_1543
TYE: THEYE_A1874(panD)
TTR: Tter_2220
HWA: HQ2363A(panD)
PIS: Pisl_1381
PAS: Pars_0404
TNE: Tneu_0357
Taxonomy
Structures PDB: 1AW8  1PPY  1PQE  1PQF  1PQH  1PT0  1PT1  1PYQ  1PYU  1UHD  
     1UHE  2C45  2EEO  
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:381298]
Williamson JM, Brown GM.
Purification and properties of L-Aspartate-alpha-decarboxylase, an
enzyme that catalyzes the formation of beta-alanine in Escherichia
coli.
J. Biol. Chem. 254 (1979) 8074-82.
Escherichia coli [GN:eco ece]
Other DBs ExplorEnz - The Enzyme Database: 4.1.1.11
IUBMB Enzyme Nomenclature: 4.1.1.11
ExPASy - ENZYME nomenclature database: 4.1.1.11
BRENDA, the Enzyme Database: 4.1.1.11
CAS: 9024-58-2
DBGET integrated database retrieval system