KEGG   ENZYME: 4.1.1.2Help
Entry
EC 4.1.1.2                  Enzyme                                 
Name
oxalate decarboxylase;
oxalate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
oxalate carboxy-lyase (formate-forming)
Reaction(IUBMB)
oxalate + H+ = formate + CO2 [RN:R00522]
Reaction(KEGG)
Substrate
oxalate [CPD:C00209];
H+ [CPD:C00080]
Product
formate [CPD:C00058];
CO2 [CPD:C00011]
Comment
The enzyme from Bacillus subtilis contains manganese and requires O2 for activity, even though there is no net redox change.
Pathway
Glyoxylate and dicarboxylate metabolism
Metabolic pathways
Orthology
K01569  
oxalate decarboxylase
Genes
ETA: 
ETA_13730(oxdD)
EBI: 
EbC_38010(oxdD)
PLU: 
PAY: 
SPE: 
SMAF: 
SMW: 
DDD: 
PAM: 
PANA_1564(oxdD)
PLF: 
PAJ: 
PAJ_0903(oxdD)
PAQ: 
PAGR_g2580
PVA: 
Pvag_pPag30056(oxdC)
BMA: 
BMAA1259
BMV: 
BMASAVP1_0231(oxdD)
BML: 
BMA10229_0503(oxdD)
BMN: 
BMA10247_A1067(oxdD)
BPS: 
BPSS0965
BPM: 
BURPS1710b_A2575
BPL: 
BURPS1106A_A1331(oxdD)
BPD: 
BURPS668_A1413(oxdD)
BPZ: 
BP1026B_II1057
BPQ: 
BPC006_II1342
BTE: 
BTH_II1426
BVI: 
Bcep1808_5109
BUR: 
Bcep18194_B1256
BCN: 
Bcen_3780
BCH: 
Bcen2424_4588
BCM: 
Bcenmc03_5717
BCJ: 
BCAM1765
BAM: 
Bamb_4014
BAC: 
BamMC406_4476
BGL: 
bglu_1g07960
BGD: 
bgla_1g08510 bgla_2g07050
BUK: 
MYA_4103
ATU: 
Atu4771
ARA: 
Arad_7183
AGR: 
AGROH133_13126
BJA: 
blr0281
BJU: 
BJ6T_14650 BJ6T_62210 BJ6T_62890
BRS: 
S23_13380
RPB: 
RPB_0200
RPT: 
Rpal_1526
AZC: 
AZC_1348
SNO: 
Snov_3533
MEA: 
Mex_1p0218(oxdC)
MCH: 
Mchl_0371
MRD: 
Mrad2831_1525
MPO: 
Mpop_0402
BID: 
Bind_0985
MSL: 
Msil_0110 Msil_2183 Msil_2678
HMC: 
HYPMC_0670(oxdD)
MSC: 
BN69_2033
PSF: 
PSE_0791(oxdD)
GOH: 
B932_0545 B932_0548
BSU: 
BSU18670(yoaN) BSU33240(oxdC)
BSR: 
I33_2097(oxdD) I33_3439
BSL: 
A7A1_2541
BSH: 
BSU6051_18670(yoaN) BSU6051_33240(oxdC)
BSY: 
I653_09720 I653_16090
BSS: 
BSUW23_16280(oxdC)
BST: 
GYO_2251(oxdD) GYO_3633
BSO: 
BSNT_04956(oxdC)
BSN: 
BSn5_00710 BSn5_07540
BSQ: 
B657_18670(yoaN) B657_33240(oxdC)
BSUB: 
BEST7613_2358 BEST7613_3593(yoaN) BEST7613_6471(oxdC)
BSX: 
C663_1932 C663_3192(oxdC)
BLI: 
BL00821(oxdC)
BLD: 
BLi03275(yoaN1) BLi03580(oxdC)
BAO: 
BAMF_2152(oxdC1) BAMF_3167(oxdC)
BAY: 
RBAM_020670(oxdC1) RBAM_030390(oxdC)
BAQ: 
BACAU_2075(oxdC1) BACAU_3063(oxdC3)
BYA: 
BANAU_2218(oxdC1) BANAU_3228(oxdC3)
BAMP: 
B938_10680 B938_15555
BAML: 
BAM5036_1994(oxdC) BAM5036_2951(oxdC)
BAZ: 
BAMTA208_05710(oxdC1) BAMTA208_16835(oxdC)
BQL: 
LL3_02435(oxdC) LL3_03450(oxdC)
BXH: 
BAXH7_01194(oxdC1) BAXH7_03438(oxdC)
BQY: 
MUS_2496(oxdC1) MUS_3634(oxdC)
BAMI: 
KSO_003965 KSO_009085
BAE: 
BATR1942_09125 BATR1942_14555
BCE: 
BC1031
BCB: 
BCB4264_A1062
BCG: 
BCG9842_B4237
BTB: 
BMB171_C0905
BTT: 
HD73_1185
BTC: 
CT43_CH0973
BTG: 
BTB_c10880(oxdD)
BTI: 
BTG_15800
BTN: 
BTF1_02900
BTHT: 
H175_ch0987
BCL: 
ABC0838
BPU: 
BPUM_0805(oxdC) BPUM_2904
BJS: 
MY9_2041 MY9_3369
GMC: 
GY4MC1_1762
LSP: 
Bsph_3039
BBE: 
BBR47_50580
PJD: 
Pjdr2_1982
GYM: 
GYMC10_4696
PPY: 
PPE_02229
PPM: 
PPSC2_c2459
PPO: 
PPM_2217(oxdC)
PTA: 
HPL003_20920
SIV: 
SSIL_1874
SMU: 
SMU_139
SMJ: 
SMULJ23_0117(oxdC)
SMUT: 
SMUGS5_00600
CBO: 
CBO0864(oxdD)
CBA: 
CLB_0903(oxdD)
CBH: 
CLC_0917(oxdD)
CBY: 
CLM_1003(oxdD)
CBL: 
CLK_0281(oxdD)
CBB: 
CLD_3707(oxdD)
CBI: 
CLJ_B0900(oxdD)
CBF: 
CLI_0942(oxdD)
CBM: 
CBF_0913
CBJ: 
H04402_00930
MSM: 
MSMEG_2254
MSG: 
MSMEI_2198
MSA: 
Mycsm_06251
MVA: 
Mvan_1922
MGI: 
Mflv_4437
MAB: 
MAB_4766
MMV: 
MYCMA_2613(oxdC)
MMI: 
MMAR_2972
MRH: 
MycrhN_2490
MLI: 
MULP_02854
NBR: 
O3I_022045
RHA: 
RHA1_ro00201
RER: 
RER_36440
ROP: 
ROP_03260
SRT: 
Srot_2024
SBH: 
SBI_08434
NML: 
Namu_2283
MAU: 
Micau_5168
MIL: 
ML5_3120
VMA: 
VAB18032_23000
PUV: 
PUV_11220
ACM: 
AciX9_3926 AciX9_4412
GMA: 
AciX8_2470 AciX8_2544
TSA: 
AciPR4_0039
SUS: 
Acid_0839
SACI: 
Sinac_7471
SYN: 
sll1358
SYZ: 
MYO_19830
SYY: 
SYNGTS_0976(sll1358)
SYT: 
SYNGTI_0976(sll1358)
SYS: 
SYNPCCN_0975(sll1358)
SYQ: 
SYNPCCP_0975(sll1358)
SYC: 
syc1717_d
SYF: 
Synpcc7942_2388
SYNE: 
Syn6312_3194
 » show all
Taxonomy
Reference
1  [PMID:13367015]
  Authors
HAYAISHI O, JAKOBY WB, OHMURA E.
  Title
Enzymatic decarboxylation of oxalic acid.
  Journal
J. Biol. Chem. 222 (1956) 435-46.
Reference
2  [PMID:10960116]
  Authors
Tanner A, Bornemann S.
  Title
Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase.
  Journal
J. Bacteriol. 182 (2000) 5271-3.
  Organism
Bacillus subtilis [GN:bsu]
Reference
3  [PMID:11546787]
  Authors
Tanner A, Bowater L, Fairhurst SA, Bornemann S.
  Title
Oxalate decarboxylase requires manganese and dioxygen for activity. Overexpression and characterization of Bacillus subtilis YvrK and YoaN.
  Journal
J. Biol. Chem. 276 (2001) 43627-34.
  Organism
Bacillus subtilis [GN:bsu]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9024-97-9
DBGET integrated database retrieval system