| Entry |
|
|---|
| Name |
4-carboxymuconolactone decarboxylase;
gamma-4-carboxymuconolactone decarboxylase;
4-carboxymuconolactone carboxy-lyase;
2-carboxy-2,5-dihydro-5-oxofuran-2-acetate carboxy-lyase
(4,5-dihydro-5-oxofuran-2-acetate-forming) |
|---|
| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
 |
|---|
| Sysname |
(R)-2-carboxy-2,5-dihydro-5-oxofuran-2-acetate carboxy-lyase
(4,5-dihydro-5-oxofuran-2-acetate-forming) |
|---|
| Reaction(IUBMB) |
(R)-2-carboxy-2,5-dihydro-5-oxofuran-2-acetate =
4,5-dihydro-5-oxofuran-2-acetate + CO2 [RN:R03470] |
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| Reaction(KEGG) |
R03470
 |
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| Substrate |
(R)-2-carboxy-2,5-dihydro-5-oxofuran-2-acetate |
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| Product |
4,5-dihydro-5-oxofuran-2-acetate [CPD:C03586];
CO2 [CPD:C00011] |
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| Pathway |
PATH: ec00362 Benzoate degradation via hydroxylation
PATH: ec01100 Metabolic pathways |
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| Orthology |
KO: K01607 4-carboxymuconolactone decarboxylase |
|---|
| Genes |
EFE: EFER_1631(pcaC)
YPE: YPO1999 YPO3649
YPK: y0218 y2310
YPM: YP_1846 YP_3898
YPA: YPA_1381 YPA_3662
YPN: YPN_1479 YPN_3522
YPP: YPDSF_0256 YPDSF_1124
YPS: YPTB1991 YPTB3581
PAY: PAU_03771
ESA: ESA_00713
KPN: KPN_01543
KPE: KPK_2911(pcaC)
KPU: KP1_2560
CKO: CKO_03053
SPE: Spro_2504
MSU: MS0180
XCC: XCC0371(pcaC)
XCB: XC_0383
XCA: xccb100_0397(pcaC)
XCV: XCV0385(pcaC) XCV2352
XAC: XAC0371(pcaC)
XOO: XOO0486(pcaC)
XOM: XOO_0453
SML: Smlt1304
VPA: VPA1141
PPR: PBPRA1967
PAE: PA0232(pcaC) PA4486
PAU: PA14_02850(pcaC) PA14_58220
PAP: PSPA7_0318(pcaC)
PAG: PLES_02291(pcaC)
PPU: PP_1381(pcaC) PP_3648
PPF: Pput_2082 Pput_4342
PPG: PputGB1_4433
PST: PSPTO_2342(pcaC-1) PSPTO_4478(pcaC-2)
PSB: Psyr_2126 Psyr_4169
PSP: PSPPH_2100(pcaC1) PSPPH_4178(pcaC2)
PFL: PFL_0890(pcaC) PFL_1325(pcaC)
PFO: Pfl01_0832 Pfl01_1275 Pfl01_3235
PEN: PSEEN1068 PSEEN1169(pcaC) PSEEN2030
PMY: Pmen_0850 Pmen_3442
PSA: PST_0930 PST_1259(pcaC)
AVN: Avin_38170(pcaC)
PAR: Psyc_0750
PCR: Pcryo_0745
PRW: PsycPRwf_0900
ACI: ACIAD1710(pcaC) ACIAD2278 ACIAD2538
ACB: A1S_1886 A1S_2332
ABM: ABSDF1189 ABSDF2018(pcaC)
ABY: ABAYE1144 ABAYE1679(pcaC) ABAYE2328
ABC: ACICU_02534
ABN: AB57_2765
ABB: ABBFA_001109
SON: SO_0083
SFR: Sfri_3646 Sfri_3873
SAZ: Sama_2707
SBL: Sbal_3703 Sbal_4266
SBM: Shew185_0083
SBN: Sbal195_0089 Sbal195_0681
SBP: Sbal223_0086
SLO: Shew_2734 Shew_3046
SHE: Shewmr4_0089 Shewmr4_3382
SHM: Shewmr7_0571
SHN: Shewana3_3552
SWD: Swoo_4049
CPS: CPS_1326(pcaC) CPS_3139
MMW: Mmwyl1_1479 Mmwyl1_2482
CVI: CV_3288(pcaC)
RSO: RS03072(RSp1472) RSc2249(pcaC)
RPI: Rpic_2454 Rpic_2477 Rpic_3905
RPF: Rpic12D_2061 Rpic12D_2083 Rpic12D_4019
REU: Reut_A0521 Reut_B5022 Reut_B5696
REH: H16_A0535 H16_B1443 H16_B2288(pcaCD)
RME: Rmet_4016
CTI: RALTA_B0454
BMA: BMA1373 BMAA1291(pcaC) BMAA2093
BMV: BMASAVP1_0268(pcaC) BMASAVP1_1121 BMASAVP1_1204 BMASAVP1_A1863
BML: BMA10229_0538(pcaC) BMA10229_1401 BMA10229_1487 BMA10229_A0034
BMN: BMA10247_1134 BMA10247_A0060(pcaC-2) BMA10247_A1029(pcaC-1)
BMA10247_A2386(pcaC-3)
BPS: BPSL1488 BPSS0047(pcaC) BPSS0939 BPSS2332
BPM: BURPS1710b_2385 BURPS1710b_A1482(pcaC) BURPS1710b_A1557(pcaC)
BURPS1710b_A2542(pcaC)
BPL: BURPS1106A_2257 BURPS1106A_A0058(pcaC) BURPS1106A_A1289
BURPS1106A_A3153(pcaC)
BPD: BURPS668_2219 BURPS668_A0071(pcaC) BURPS668_A1368
BURPS668_A3267(pcaC)
BTE: BTH_I2127 BTH_I2209 BTH_II0050(pcaC) BTH_II1458 BTH_II2352
BVI: Bcep1808_1770 Bcep1808_3739 Bcep1808_4092 Bcep1808_4650
BUR: Bcep18194_A5144 Bcep18194_B1956 Bcep18194_B2446 Bcep18194_B3125
BCN: Bcen_4279 Bcen_4700 Bcen_5109 Bcen_6236
BCH: Bcen2424_1843 Bcen2424_3662 Bcen2424_4087 Bcen2424_5750
BCM: Bcenmc03_1867 Bcenmc03_3859 Bcenmc03_6820
BAM: Bamb_1781 Bamb_4316 Bamb_5021
BXE: Bxe_A2370 Bxe_B0647(pcaC) Bxe_B0976 Bxe_B1965 Bxe_C0504
BPY: Bphyt_4316
BPE: BP0231(pcaC)
BPA: BPP0880 BPP3636(pcaC)
BBR: BB0973 BB1075 BB4071(pcaC)
POL: Bpro_1856 Bpro_1901
PNA: Pnap_2188 Pnap_2661
VEI: Veis_2974
AZO: azo2506(cmd) azo2959 azo3958(pcaC)
DAR: Daro_2931
HHE: HH1468
GSU: GSU1313
SAT: SYN_02871
MLO: mlr7207
MES: Meso_0805 Meso_2049 Meso_2527 Meso_2960
SME: SM_b20578(pcaC)
ATU: Atu4541(pcaC) Atu5225
ATC: AGR_L_653 AGR_pAT_316
RET: RHE_PD00084(pcaCd2) RHE_PD00115(pcaCd1) RHE_PE00058(pcaCe)
RHE_PF00193(pcaCf)
RLE: pRL110088(pcaC) pRL90120
BME: BMEII0637
BMF: BAB2_0597(pcaC)
BMB: BruAb2_0582(pcaC)
BMS: BRA0644(pcaC)
BOV: BOV_A0606(pcaC)
OAN: Oant_3726
BJA: bll1385(pcaC) blr5669(pcaC) bsl4577
BRA: BRADO5848(pcaC) BRADO6697
BBT: BBta_0837 BBta_1984(pcaC)
RPA: RPA4740(pcaC)
RPB: RPB_0830 RPB_1568
RPD: RPD_0939
RPE: RPE_4839
CCR: CC_2411
SIL: SPO1589 SPO2768 SPOA0045(pcaC) SPOA0346
SIT: TM1040_0559 TM1040_0755
RSP: RSP_2524
RSH: Rsph17029_1186
RSQ: Rsph17025_1996
JAN: Jann_1592 Jann_4162
RDE: RD1_3274 RD1_3773(pcaC)
PDE: Pden_3215 Pden_3492
DSH: Dshi_1323 Dshi_2361 Dshi_3478(pcaC)
HNE: HNE_0019
SWI: Swit_0311 Swit_1070
GBE: GbCGDNIH1_0525 GbCGDNIH1_0956
ACR: Acry_0028 Acry_3404
GDI: GDI_2770(pcaC) GDI_2847
MAG: amb3965
BCA: BCE_2858
BCZ: BCZK1757(pcaC) BCZK2554
BTL: BALH_1719(pcaC) BALH_2538
BCL: ABC2008
LWE: lwe0628
ESI: Exig_2857
EAT: EAT1b_0229
LLA: L35675(pcaC)
LLC: LACR_1625 LACR_2239
LLM: llmg_0970 llmg_2230(pcaC)
LPL: lp_2852
LSA: LSA1190 LSA1776
LCA: LSEI_1214
CKL: CKL_2503
MTU: Rv0771
MRA: MRA_0780
MBO: Mb0794
MBB: BCG_0823
MPA: MAP0745c
MAV: MAV_0716(pcaC) MAV_0906(pcaC) MAV_1392(pcaC) MAV_2020(pcaC)
MAV_2164(pcaC) MAV_2165(pcaC) MAV_2831(pcaC) MAV_3238(pcaC)
MAV_3552(pcaC) MAV_3958(pcaC) MAV_4685(pcaC)
MSM: MSMEG_0905(pcaC) MSMEG_2530(pcaC) MSMEG_2604(pcaC)
MSMEG_3562(pcaC) MSMEG_5814(pcaC) MSMEG_5856(pcaC) MSMEG_6150
MSMEG_6370(pcaC)
MUL: MUL_0480
MVA: Mvan_3396 Mvan_4934 Mvan_5154
MGI: Mflv_0527 Mflv_1603 Mflv_1912
MAB: MAB_1221
MMC: Mmcs_1701 Mmcs_4575 Mmcs_4793
MKM: Mkms_4879
MJL: Mjls_4958 Mjls_5179
CGL: NCgl2310(cgl2393) NCgl2312(cgl2395)
CGB: cg2626(pcaL)
CGT: cgR_2275 cgR_2277
CEF: CE2296 CE2298
RHA: RHA1_ro01338(pcaL) RHA1_ro02550(pcaC) RHA1_ro04660
RER: RER_08380
SCO: SCO6697(pcaL)
SMA: SAV_1706(pcaL1) SAV_6757
CMI: CMM_0541
ART: Arth_4074
AAU: AAur_4040(pcaC)
RSA: RSal33209_0095
KRH: KRH_06080(pcaC)
NCA: Noca_1011
FRE: Franean1_4519
SEN: SACE_3510(pcaC)
RXY: Rxyl_1577
SUS: Acid_0244
SRU: SRU_2774(pcaC)
SYD: Syncc9605_0521
DRA: DR_0973 DR_1204
DGE: Dgeo_0717
TTH: TTC1144
TTJ: TTHA1508
MMA: MM_0143
MTH: MTH234
RCI: RCIX2594(cmd-2) RRC209(cmd-3)
SSO: SSO2884(pcaC)
SAI: Saci_1814
 |
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| Structures |
PDB: 2AF7 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5330966]
Ornston LN.
The conversion of catechol and protocatechuate to beta-ketoadipate
by Pseudomonas putida. 3. Enzymes of the catechol pathway.
J. Biol. Chem. 241 (1966) 3795-9.
Pseudomonas putida |
|---|
Reference
Authors
Title
Journal
|
2
Ornston, L.N.
Conversion of catechol and protocatechuate to beta-ketoadipate
(Pseudomonas putida).
Methods Enzymol. 17A (1970) 529-549. |
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| Other DBs |
ExplorEnz - The Enzyme Database: 4.1.1.44
IUBMB Enzyme Nomenclature: 4.1.1.44
ExPASy - ENZYME nomenclature database: 4.1.1.44
BRENDA, the Enzyme Database: 4.1.1.44
CAS: 37289-46-6 |
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