KEGG   ENZYME: 4.1.1.49Help
Entry
EC 4.1.1.49                 Enzyme                                 
Name phosphoenolpyruvate carboxykinase (ATP);
phosphopyruvate carboxylase (ATP);
phosphoenolpyruvate carboxylase;
phosphoenolpyruvate carboxykinase;
phosphoenolpyruvate carboxykinase;
phosphopyruvate carboxykinase (adenosine triphosphate);
PEP carboxylase;
PEP carboxykinase;
PEPCK (ATP);
PEPK;
PEPCK;
phosphoenolpyruvic carboxylase;
phosphoenolpyruvic carboxykinase;
phosphoenolpyruvate carboxylase (ATP);
phosphopyruvate carboxykinase;
ATP:oxaloacetate carboxy-lyase (transphosphorylating)
Class Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname ATP:oxaloacetate carboxy-lyase (transphosphorylating;
phosphoenolpyruvate-forming)
Reaction(IUBMB) ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO2 [RN:R00341]
Reaction(KEGG) R00341
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Substrate ATP [CPD:C00002];
oxaloacetate [CPD:C00036]
Product ADP [CPD:C00008];
phosphoenolpyruvate [CPD:C00074];
CO2 [CPD:C00011]
Pathway PATH: ec00010  Glycolysis / Gluconeogenesis
PATH: ec00020  Citrate cycle (TCA cycle)
PATH: ec00620  Pyruvate metabolism
PATH: ec00710  Carbon fixation in photosynthetic organisms
PATH: ec01100  Metabolic pathways
Orthology KO: K01610  phosphoenolpyruvate carboxykinase (ATP)
Genes ATH: AT4G37870(PCK1) AT5G65690(PCK2)
POP: POPTR_719763 POPTR_816402
RCU: RCOM_0188120 RCOM_1584090
VVI: 100244738(GSVIVT00011154001)
OSA: 4332293(Os03g0255500) 4348268(Os10g0204400)
ZMA: 100279748
PPP: PHYPADRAFT_136941 PHYPADRAFT_139716 PHYPADRAFT_210293
CRE: CHLREDRAFT_196612(PCK1b|PCK1a)
CME: CMN285C
SCE: YKR097W(PCK1)
AGO: AGOS_AFR292W
KLA: KLLA0A00484g
LTH: KLTH0E00902g
DHA: DEHA0E19569g
PIC: PICST_71471(PCK1)
PPA: PAS_FragB_0061
VPO: Kpol_1043p75
LEL: LELG_00055
ZRO: ZYRO0B16456g
CAL: CaO19.7514(PCK1)
CTP: CTRG_01062
CDU: CD36_25230(PCK1)
CGR: CAGL0H06633g
YLI: YALI0C16995g
NCR: NCU09873
PAN: PODANSg2883
MGR: MGG_00450
FGR: FG08601.1
ANI: AN1918.2
AFM: AFUA_6G07720
AOR: AO090003000174
ANG: An11g02550
AFV: AFLA_036370
PCS: Pc12g09360
NFI: NFIA_053390
CIM: CIMG_01264
URE: UREG_01196
SSL: SS1G_02281
BFU: BC1G_14651
CNE: CNI03590
CNB: CNBH3420
LBC: LACBIDRAFT_234370
UMA: UM05130.1
MGL: MGL_1615
MBR: MONBRDRAFT_18344
DDI: DDB_0231108(pckA)
PFA: PF13_0234
PFD: PFDG_01662
PFH: PFHG_02125
PYO: PY01233
PCB: PC001162.02.0
PBE: PB001070.00.0
PKN: PKH_121170
PVX: PVX_083035
TAN: TA20590
TPV: TP01_0495
BBO: BBOV_I003550
TGO: TGME49_089650
TET: TTHERM_00420030
PTM: GSPATT00013074001 GSPATT00015084001 GSPATT00015873001
     GSPATT00031820001
TBR: Tb927.2.4210
TCR: 507547.90 508441.20
LMA: LmjF27.1805 LmjF27.1810
LIF: LinJ27.1470
LBZ: LbrM27_V2.1920
ECO: b3403(pck)
ECJ: JW3366(pck)
ECD: ECDH10B_3578(pck)
EBW: BWG_3094(pck)
ECE: Z4758(pckA)
ECS: ECs4245
ECF: ECH74115_4709(pckA)
ETW: ECSP_4353(pck)
ECG: E2348C_3647(pck)
ECC: c4176(pckA)
ECI: UTI89_C3903(pckA)
ECP: ECP_3489
ECV: APECO1_3061(pckA)
ECW: EcE24377A_3877(pckA)
ECX: EcHS_A3600(pckA)
ECM: EcSMS35_3682(pckA)
ECY: ECSE_3666
ECL: EcolC_0310
ECK: EC55989_3809(pck)
ECQ: ECED1_4063(pck)
ECR: ECIAI1_3544(pck)
ECT: ECIAI39_3881(pck)
ECZ: ECS88_3790(pck)
EUM: ECUMN_3862(pck)
ELF: LF82_1601(pck)
EBL: B21_03207(pckA)
EBD: ECBD_0342
EBR: ECB_03255(pckA)
EOH: ECO103_4121(pck)
EOI: ECO111_4212(pck)
EOJ: ECO26_4491(pck)
EFE: EFER_3369(pck)
STY: STY4296(pckA)
STT: t4006(pckA)
SPT: SPA3365(pckA)
SEK: SSPA3140
SPQ: SPAB_04356
SEI: SPC_3569(pckA)
SEC: SC3432(pckA)
SEH: SeHA_C3807(pckA)
SEE: SNSL254_A3773(pckA)
SEW: SeSA_A3698(pckA)
SEA: SeAg_B3701(pckA)
SED: SeD_A3869(pckA)
SEG: SG3938(pckA)
SET: SEN3326(pckA)
SES: SARI_04115
STM: STM3500(pckA)
YPE: YPO0138(pckA)
YPK: y3918(pckA)
YPM: YP_0139(pckA)
YPA: YPA_3331
YPN: YPN_3927
YPG: YpAngola_A3739(pckA)
YPP: YPDSF_0065
YPS: YPTB3762(pckA)
YPI: YpsIP31758_3978(pckA)
YPY: YPK_0174
YPB: YPTS_3958
YEN: YE3986(pck)
SFL: SF3422(pckA)
SFX: S4341(pckA)
SFV: SFV_3408(pckA)
SSN: SSON_3534(pckA)
SBO: SBO_3390(pckA)
SBC: SbBS512_E3782(pckA)
SDY: SDY_3673(pckA)
ECA: ECA4106(pckA)
PCT: PC1_3896
PWA: Pecwa_4073
ETA: ETA_32170(pckA)
PLU: plu0100(pckA)
PAY: PAU_00083(pckA)
WBR: WGLp577(pckA)
SGL: SG2317
ENT: Ent638_3816
ESA: ESA_04336
CTU: Ctu_39120(pckA)
KPN: KPN_02285(pckA) KPN_03773(pckA)
KPE: KPK_0343(pckA) KPK_2024
KPU: KP1_3400(pckA) KP1_5104(pckA)
CKO: CKO_04825
SPE: Spro_2098 Spro_4617
PMR: PMI3015(pckA)
EIC: NT01EI_3643
ETR: ETAE_3277(pckA)
HDE: HDEF_0382(pckA)
DDA: Dd703_0326
DDC: Dd586_3814
DZE: Dd1591_0246
HIN: HI0809(pckA)
HIT: NTHI0973(pckA)
HIP: CGSHiEE_08015
HIQ: CGSHiGG_07540
HDU: HD1331(pckA)
HAP: HAPS_0717(pckA)
HSO: HS_1628(pckA)
HSM: HSM_0381
PMU: PM1542(pckA)
MSU: MS2293(pckA)
APL: APL_0800(pckA)
APJ: APJL_0805(pckA)
APA: APP7_0859
ASU: Asuc_0221
AAP: NT05HA_1606
AAT: D11S_0689
VCH: VC2738
VCO: VC0395_A2310(pckA)
VCM: VCM66_2658(pckA)
VCJ: VCD_001630
VVU: VV1_0881
VVY: VV0207
VPA: VP0129
VHA: VIBHAR_00597
VSP: VS_0131
VEX: VEA_001896
VFI: VF_2478(pck)
VFM: VFMJ11_2601(pckA)
VSA: VSAL_I2928(pckA)
PPR: PBPRA3485
PAE: PA5192(pckA)
PAU: PA14_68580(pckA)
PAP: PSPA7_5935(pckA)
PAG: PLES_55861(pckA)
PPF: Pput_0268
PPG: PputGB1_0278
PPW: PputW619_4959
PST: PSPTO_0239(pckA)
PSB: Psyr_0168
PSP: PSPPH_5022(pckA)
PFL: PFL_0284(pckA)
PFO: Pfl01_0268
PFS: PFLU0267(pckA)
PEN: PSEEN0234(pck)
PMY: Pmen_0368
PSA: PST_0293(pckA)
AVN: Avin_05450(pckA)
SON: SO_0162(pckA)
SDN: Sden_0117
SFR: Sfri_0101
SAZ: Sama_0165
SBL: Sbal_4210
SBM: Shew185_0145
SBN: Sbal195_0149
SBP: Sbal223_0148
SLO: Shew_3623
SPC: Sputcn32_3571
SSE: Ssed_4362
SPL: Spea_0140
SHE: Shewmr4_0152
SHM: Shewmr7_0147
SHN: Shewana3_0147
SHW: Sputw3181_3708
SHL: Shal_4178
SWD: Swoo_4740
SWP: swp_0182
ILO: IL0273(pckA)
CPS: CPS_4595(pckA)
PHA: PSHAa0228(pck)
PAT: Patl_2282
SDE: Sde_0992
MAQ: Maqu_3754
AMC: MADE_03951
PIN: Ping_0093
TTU: TERTU_1174(pckA)
CBU: CBU_2092(pckA)
CBS: COXBURSA331_A2217(pckA)
CBD: CBUD_2191(pckA)
CBG: CbuG_2094(pckA)
CBC: CbuK_2142(pckA)
FTU: FTT_0449(pckA)
FTF: FTF0449(pckA)
FTW: FTW_1621(pckA)
FTL: FTL_1616
FTH: FTH_1563(pckA)
FTA: FTA_1704(pckA)
FTM: FTM_1454(pckA)
FTN: FTN_0540(pckA)
FPH: Fphi_0297
AEH: Mlg_2591
HCH: HCH_00561(pckA)
CSA: Csal_2657
ABO: ABO_0275(pckA)
MMW: Mmwyl1_3504
AHA: AHA_0565(pckA)
ASA: ASA_3771(pckA)
TAU: Tola_0416 Tola_0419
BCI: BCI_0013(pckA)
KKO: Kkor_1676
TDN: Suden_1696
CJE: Cj0932c(pckA)
CJR: CJE1010(pckA)
CJJ: CJJ81176_0939(pckA)
CJU: C8J_0869(pckA)
CJD: JJD26997_0882(pckA)
CFF: CFF8240_1294(pckA)
CCV: CCV52592_0965(pckA)
CHA: CHAB381_1486(pckA)
CCO: CCC13826_1509(pckA)
CLA: Cla_1196(pckA)
ABU: Abu_1227(pckA)
SDL: Sdel_0606
NIS: NIS_0043(pckA)
SUN: SUN_1431(pckA)
NAM: NAMH_0090(pckA)
GME: Gmet_3169
GUR: Gura_0871
GBM: Gbem_0733
GEM: GM21_0748
PPD: Ppro_3603
DMA: DMR_26700
DSA: Desal_0782
DAL: Dalk_2228
HOH: Hoch_2005
SAT: SYN_02086
MLO: mlr5096
MES: Meso_3502
PLA: Plav_0109
SME: SMc02562(pckA)
SMD: Smed_3253
ATU: Atu0035(pckA)
ATC: AGR_C_56
ARA: Arad_0047(pckA)
AVI: Avi_0042(pckA)
RET: RHE_CH00037(pckA)
REC: RHECIAT_CH0000039(pckA)
RLE: RL0037(pckA)
RLT: Rleg2_3970
RLG: Rleg_4297
RHI: NGR_c33940(pckA)
LAS: CLIBASIA_03595(pckA)
BME: BMEI2037
BMC: BAbS19_I19580
BMS: BR2089(pckA)
BCS: BCAN_A2135(pckA)
BMR: BMI_I2111(pckA)
OAN: Oant_0829
BJA: bll8141(pckA)
BRA: BRADO0741(pckA)
BBT: BBta_7365(pckA)
RPA: RPA0360(pckA)
RPB: RPB_0461
RPC: RPC_0599
RPD: RPD_0365
RPE: RPE_0819
RPT: Rpal_0363
NWI: Nwi_0350
NHA: Nham_0445
OCA: OCAR_7573(pckA)
XAU: Xaut_2843
AZC: AZC_4063
MEX: Mext_1639
MEA: Mex_1p1533(pck)
MDI: METDI2307(pck)
MRD: Mrad2831_3144
MET: M446_0223
MPO: Mpop_1593
MCH: Mchl_1921
MNO: Mnod_5431
MSL: Msil_1375
SIL: SPO0709(pckA)
SIT: TM1040_2442
RSP: RSP_1680(pckA)
RSH: Rsph17029_0313
RSQ: Rsph17025_2566
RSK: RSKD131_3080
JAN: Jann_0535
RDE: RD1_1376(pckA)
PDE: Pden_2852
DSH: Dshi_0213(pckA)
MMR: Mmar10_1100
HNE: HNE_2705(pckA)
NAR: Saro_2908
SAL: Sala_2046
SWI: Swit_0403 Swit_5391
ELI: ELI_02140
ACR: Acry_1886
GDI: GDI_0610(pckA)
GDJ: Gdia_1393
RCE: RC1_2822(pckA)
MGM: Mmc1_0369
BSU: BSU30560(pckA)
BHA: BH3302(pckA)
BAN: BA5019(pckA)
BAR: GBAA5019(pckA)
BAA: BA_5438
BAT: BAS4661
BAH: BAMEG_5056(pckA)
BAI: BAA_5034(pckA)
BCE: BC4762
BCA: BCE_4916(pckA)
BCZ: BCZK4518(pckA)
BCR: BCAH187_A4906(pckA)
BCB: BCB4264_A4879(pckA)
BCU: BCAH820_4887(pckA)
BCG: BCG9842_B0361(pckA)
BCQ: BCQ_4583(pckA)
BCX: BCA_4894(pckA)
BCY: Bcer98_3438
BTK: BT9727_4501(pckA)
BTL: BALH_4341(pckA)
BWE: BcerKBAB4_4595
BLI: BL00839(pckA)
BLD: BLi03197(pckA)
BCL: ABC2879(pckA)
BAY: RBAM_027580(pckA)
BPU: BPUM_2687(pckA)
OIH: OB2315(pckA)
GKA: GK2850
GTN: GTNG_2751
GWC: GWCH70_2779
GYC: GYMC61_0658
AFL: Aflv_0413(pckA)
SAU: SA1609(pckA)
SAV: SAV1791(pckA)
SAW: SAHV_1776(pckA)
SAM: MW1729(pckA)
SAR: SAR1871(pckA)
SAS: SAS1712
SAC: SACOL1838(pckA)
SAB: SAB1646(pckA)
SAA: SAUSA300_1731(pckA)
SAX: USA300HOU_1778(pckA)
SAO: SAOUHSC_01910
SAJ: SaurJH9_1842
SAH: SaurJH1_1878
SAE: NWMN_1681(pckA)
SAD: SAAV_1801
SEP: SE1459
SER: SERP1353(pckA)
SHA: SH1137(pckA)
SSP: SSP0975
SCA: Sca_1390(pckA)
LSP: Bsph_4252
ESI: Exig_2285
EAT: EAT1b_0743
MCL: MCCL_1499(pckA)
BBE: BBR47_48590(ppcK)
SMU: SMU.1389(pckA)
SGO: SGO_1656
SUB: SUB1583
LPL: lp_3418(pck)
LPJ: JDM1_2721(pck)
LJO: LJ0149
LJF: FI9785_216(pckA)
LAC: LBA0466
LSL: LSL_0395(pckA)
LCA: LSEI_1820
LCB: LCABL_20410(pck)
LGA: LGAS_0152
LRH: LGG_01876(pck)
LRL: LC705_01857(pck)
CKL: CKL_2699(pck)
CKR: CKR_2394
CPY: Cphy_3853
AOE: Clos_0884
VPR: Vpar_0207
DSY: DSY4203(pck)
DHD: Dhaf_1134
PTH: PTH_1008(pckA)
DAU: Daud_1563
HMO: HM1_2773(pckA)
EEL: EUBELI_01169
ERE: EUBREC_2002
TTE: TTE1783(pckA)
TEX: Teth514_1285
MTA: Moth_0633 Moth_1893
CPO: COPRO5265_0282(pckA)
NTH: Nther_1874
RXY: Rxyl_0680
SHI: Shel_02560
LIL: LA0251(pckA)
LIC: LIC10216(pckA)
LBJ: LBJ_2789(pckA)
LBL: LBL_0282(pckA)
LBI: LEPBI_I2989(pck)
LBF: LBF_2886(pckA)
ACA: ACP_2868(pckA)
SUS: Acid_1079 Acid_3468
BTH: BT_2790
BFR: BF4446
BFS: BF4244(pckA)
BVU: BVU_0976 BVU_0983
PGI: PG1676(pckA)
PGN: PGN_0434
PDI: BDI_2805
APS: CFPG_593
SRU: SRU_1835(pckA) SRU_2373(pckA)
RMR: Rmar_1197
CPI: Cpin_6930
PHE: Phep_4091
GFO: GFO_0105(pckA)
FJO: Fjoh_1366
FPS: FP2375(pckA)
FBA: FIC_02307
COC: Coch_1952
RBI: RB2501_03670 RB2501_08345
BBL: BLBBGE_077(pckA)
BPI: BPLAN_557(pck)
AAS: Aasi_1049
FNU: FN1120
LBA: Lebu_2281
MIN: Minf_0887(pckA)
GAU: GAU_2166(pckA)
EMI: Emin_0748
MAR: MAE_06160
CYT: cce_0508
CYP: PCC8801_4042
CYC: PCC7424_2776
CYH: Cyan8802_4079
HAU: Haur_4076
STI: Sthe_1319
DRA: DR_0977
DGE: Dgeo_1196
DDR: Deide_12330(pckA)
TTH: TTC1709
TTJ: TTHA0278
TME: Tmel_1237
TAF: THA_1470
FNO: Fnod_1444
KOL: Kole_0847
HLA: Hlac_2236
APE: APE_0033.1(pckA)
NMR: Nmar_0392
KCR: Kcr_0317
Taxonomy
Structures PDB: 1AQ2  1AYL  1K3C  1K3D  1OEN  1OS1  1XKV  1YGG  1YLH  1YTM  
     1YVY  2OLQ  2OLR  2PC9  2PXZ  2PY7  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:5416663]
Cannata JJ.
Phosphoenolpyruvate carboxykinase from bakers' yeast. Isolation of
the enzyme and study of its physical properties.
J. Biol. Chem. 245 (1970) 792-8.
Saccharomyces cerevisiae [GN:sce]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:14018315]
CANNATA JJ, STOPPANI AO.
Phosphopyruvate carboxylase from baker's yeast. I. Isolation,
purification, and characterization.
J. Biol. Chem. 238 (1963) 1196-207.
Saccharomyces cerevisiae [GN:sce]
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:14018316]
CANNATA JJ, STOPPANI AO.
Phosphopyruvate carboxylase from baker's yeast. II. Properties of
enzyme.
J. Biol. Chem. 238 (1963) 1208-12.
Saccharomyces cerevisiae [GN:sce]
Other DBs ExplorEnz - The Enzyme Database: 4.1.1.49
IUBMB Enzyme Nomenclature: 4.1.1.49
ExPASy - ENZYME nomenclature database: 4.1.1.49
BRENDA, the Enzyme Database: 4.1.1.49
CAS: 9073-94-3
DBGET integrated database retrieval system