| Entry |
|
|---|
| Name |
phenylalanine decarboxylase;
L-phenylalanine decarboxylase;
aromatic L-amino acid decarboxylase;
L-phenylalanine carboxy-lyase |
|---|
| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
 |
|---|
| Sysname |
L-phenylalanine carboxy-lyase (phenylethylamine-forming) |
|---|
| Reaction(IUBMB) |
L-phenylalanine = phenylethylamine + CO2 [RN:R00699] |
|---|
| Reaction(KEGG) |
R00699
 |
|---|
| Substrate |
L-phenylalanine [CPD:C00079] |
|---|
| Product |
phenylethylamine [CPD:C05332];
CO2 [CPD:C00011] |
|---|
| Cofactor |
Pyridoxal phosphate [CPD:C00018] |
|---|
| Comment |
A pyridoxal-phosphate protein. Also acts on tyrosine and other
aromatic amino acids. |
|---|
| Pathway |
PATH: ec00360 Phenylalanine metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14466899]
LOVENBERG W, WEISSBACH H, UDENFRIEND S.
Aromatic L-amino acid decarboxylase.
J. Biol. Chem. 237 (1962) 89-93.
Rattus norvegicus [GN:rno], Canis familiaris [GN:cfa], Cavia
porcellus |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6034195]
Schulz AR, Oliner L.
The possible role of thyroid aromatic amino acid decarboxylase in
thyroxine biosynthesis.
Life. Sci. 6 (1967) 873-80.
Bos taurus [GN:bta] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.1.1.53
IUBMB Enzyme Nomenclature: 4.1.1.53
ExPASy - ENZYME nomenclature database: 4.1.1.53
BRENDA, the Enzyme Database: 4.1.1.53
CAS: 9075-72-3 |
|---|
