| Entry |
|
|---|
| Name |
tagatose-bisphosphate aldolase;
D-tagatose-1,6-bisphosphate triosephosphate lyase |
|---|
| Class |
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
 |
|---|
| Sysname |
D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase
(glycerone-phosphate-forming) |
|---|
| Reaction(IUBMB) |
D-tagatose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde
3-phosphate [RN:R01069] |
|---|
| Reaction(KEGG) |
R01069
 |
|---|
| Substrate |
D-tagatose 1,6-bisphosphate [CPD:C03785] |
|---|
| Product |
glycerone phosphate [CPD:C00111];
D-glyceraldehyde 3-phosphate [CPD:C00118] |
|---|
| Comment |
Enzyme activity is stimulated by certain divalent cations. It is
involved in the tagatose 6-phosphate pathway of lactose catabolism
in bacteria. |
|---|
| Pathway |
PATH: ec00052 Galactose metabolism |
|---|
| Orthology |
KO: K01635 tagatose 1,6-diphosphate aldolase
KO: K08302 tagatose 1,6-diphosphate aldolase |
|---|
| Genes |
ZMA: 100280420
NCR: NCU04401
PAN: PODANSg7446
MGR: MGCH7_ch7g899
FGR: FG08044.1
ANI: AN2334.2
AFM: AFUA_5G10290
AOR: AO090010000514
ANG: An14g04410
AFV: AFLA_119950
PCS: Pc21g09930
NFI: NFIA_076970
CIM: CIMG_05755
SSL: SS1G_06400
BFU: BC1G_12564
ECO: b2096(gatY) b3137(kbaY)
ECJ: JW3106(kbaY) JW5343(gatY)
ECD: ECDH10B_2249(gatY) ECDH10B_3310(kbaY)
EBW: BWG_1882(gatY) BWG_2841(kbaY)
ECE: Z3259(gatY) Z4491(kbaY)
ECS: ECs2899(gatY) ECs4017(kbaY)
ECF: ECH74115_3075(gatY) ECH74115_4454(kbaY)
ETW: ECSP_2891(gatY) ECSP_4111(kbaY)
ECG: E2348C_2241(gatY) E2348C_3423(kbaY)
ECC: c2621(gatY) c3894(kbaY) c4018(gatY)
ECI: UTI89_C2369(gatY) UTI89_C3568(kbaY) UTI89_C3695(gatY)
ECP: ECP_2134(gatY) ECP_3229 ECP_3347(gatY)
ECV: APECO1_3184(gatY) APECO1_3290(kbaY) APECO1_4449(gatY)
ECW: EcE24377A_2384(gatY) EcE24377A_3619(kbaY)
ECX: EcHS_A2232(gatY) EcHS_A3329(kbaY)
ECM: EcSMS35_0968(gatY) EcSMS35_3436(kbaY)
ECY: ECSE_2365(gatY) ECSE_3423(kbaY)
ECL: EcolC_0561(kbaY) EcolC_1551(gatY)
ECK: EC55989_2351(gatY) EC55989_3557(kbaY)
ECQ: ECED1_3801(kbaY) ECED1_3913(gatY)
ECR: ECIAI1_2170(gatY) ECIAI1_3287(kbaY)
ECT: ECIAI39_0921(gatY) ECIAI39_3638(kbaY) ECIAI39_3754(gatY)
ECZ: ECS88_2238(gatY) ECS88_3525(kbaY) ECS88_3638(gatY)
EUM: ECUMN_2428(gatY) ECUMN_3621(kbaY)
ELF: LF82_0813(gatY) LF82_1138(kbaY) LF82_p521
EBL: B21_01988(gatY) B21_02955(kbaY)
EBD: ECBD_0603 ECBD_1561
EBR: ECB_02024(gatY) ECB_03004(agaY)
EOH: ECO103_3884(kbaY)
EOI: ECO111_2812(gatY) ECO111_3961(kbaY) ECO111_4081
EOJ: ECO26_3005(gatY) ECO26_4242(kbaY) ECO26_4360
EFE: EFER_4354(kbaY)
STY: STY3435(gatY)
STT: t3173(gatY)
SPT: SPA3122(gatY)
SEK: SSPA2914(gatY)
SPQ: SPAB_04063(gatY)
SEI: SPC_3327(gatY)
SEC: SC3197(gatY)
SEH: SeHA_C3551(gatY)
SEE: SNSL254_A3514(gatY)
SEW: SeSA_A3445(gatY)
SEA: SeAg_B3443(gatY)
SED: SeD_A3611(gatY)
SEG: SG3147(gatY)
SET: SEN3091(gatY)
SES: SARI_04361(kbaY)
STM: STM3253(gatY)
YPE: YPO0844(gatY)
YPK: y3229(gatY)
YPM: YP_3540(gatY)
YPA: YPA_0426(gatY)
YPN: YPN_3046(gatY)
YPG: YpAngola_A3364(gatY)
YPP: YPDSF_0670(gatY)
YPS: YPTB3088(gatY)
YPI: YpsIP31758_0929(gatY)
YPY: YPK_0982(gatY)
YPB: YPTS_3210(gatY)
SFL: SF2158(gatY)
SFX: S2284(gatY)
SFV: SFV_2151(gatY)
SSN: SSON_2144(gatY)
SBO: SBO_0917(gatY) SBO_3248(gatY)
SBC: SbBS512_E1142(gatY) SbBS512_E3636(gatY)
SDY: SDY_2269(gatY)
ECA: ECA2358
PCT: PC1_1950
PWA: Pecwa_2246 Pecwa_2393
PLU: plu0839(gatY)
PAY: PAU_00779(gatY)
ENT: Ent638_3578(kbaY)
CTU: Ctu_04400(gatY)
KPN: KPN_03543(gatY)
KPU: KP1_4847(gatY)
CKO: CKO_04537(kbaY)
SPE: Spro_2579(gatY)
PMR: PMI2145(gatY)
EIC: NT01EI_2805
ETR: ETAE_2526(gatY)
HAP: HAPS_0188(lacD)
HSO: HS_1146(lacD)
HSM: HSM_1030
AAT: D11S_1282 D11S_1283
VVU: VV2_1017(gatY)
VVY: VVA1509(gatY)
VFI: VF_A0989(gatY)
VFM: VFMJ11_A1108(gatY)
PPR: PBPRB0157(gatY) PBPRB1043(gatY)
AHA: AHA_0805
VEI: Veis_0798 Veis_2597
MLO: mlr3411
ARA: Arad_9621
AVI: Avi_5337
BJA: bll6350
BCA: BCE_1906(gatY)
BCZ: BCZK1641(gatY)
BCR: BCAH187_A2111(lacD)
BCQ: BCQ_1995
BLI: BL01900(gatY)
BLD: BLi03552(gatY)
BCL: ABC3568
BPU: BPUM_1767
SAU: SA1994(lacD)
SAV: SAV2192(lacD)
SAW: SAHV_2176(lacD)
SAM: MW2118(lacD)
SAR: SAR2283(lacD)
SAS: SAS2093
SAC: SACOL2183(lacD)
SAB: SAB2073c(lacD)
SAA: SAUSA300_2152(lacD)
SAX: USA300HOU_2185(lacD)
SAO: SAOUHSC_02452
SAJ: SaurJH9_2223
SAH: SaurJH1_2262
SAE: NWMN_2096(lacD)
SAD: SAAV_2253(lacD)
SEP: SE1784
SER: SERP1792(lacD)
SHA: SH0845(lacD)
SCA: Sca_0672(lacD)
LMO: lmo0539
LMF: LMOf2365_0568
LMH: LMHCC_2092
LMC: Lm4b_00565
LIN: lin0543
LWE: lwe0500(lacD) lwe0801(lacD)
EAT: EAT1b_1046
BBE: BBR47_58120
LLC: LACR_D03
SPY: SPy_1704(lacD.1) SPy_1919(lacD.2)
SPZ: M5005_Spy_1395(lacD.1) M5005_Spy_1635(lacD.2)
SPM: spyM18_1714 spyM18_1987
SPG: SpyM3_1482(lacD.1) SpyM3_1656(lacD.2)
SPS: SPs0385 SPs1654
SPH: MGAS10270_Spy1516(lacD1) MGAS10270_Spy1704(lacD2)
SPI: MGAS10750_Spy1508(lacD1) MGAS10750_Spy1732(lacD2)
SPJ: MGAS2096_Spy1420(lacD1) MGAS2096_Spy1660(lacD2)
SPK: MGAS9429_Spy1397(lacD1) MGAS9429_Spy1638(lacD2)
SPF: SpyM50395(lacD1) SpyM51610(lacD2)
SPA: M6_Spy1444 M6_Spy1644
SPB: M28_Spy1438(lacD.1) M28_Spy1625(lacD.2)
SOZ: Spy49_1322c(lacD1) Spy49_1587c(lacD2)
SPN: SP_1190
SPD: SPD_1050(lacD)
SPR: spr1073(lacD)
SPW: SPCG_1108(lacD)
SPX: SPG_1085(lacD)
SNE: SPN23F_10890(lacD2)
SPV: SPH_1308(lacD)
SNM: SP70585_1240(lacD)
SJJ: SPJ_1106(lacD)
SPP: SPP_1231(lacD)
SNT: SPT_1036(lacD)
SAG: SAG1928(lacD)
SAN: gbs1333 gbs1915
SAK: SAK_1887(lacD)
SMU: SMU.116(lacD2) SMU.1493(lacD)
SSA: SSA_0061 SSA_1696(lacD)
SSU: SSU05_1040 SSU05_1258
SSV: SSU98_1054 SSU98_1055 SSU98_1273
SSB: SSUBM407_0515(lacD2) SSUBM407_0694(lacD2) SSUBM407_0884(lacD1)
SSI: SSU0895(lacD) SSU1095(lacD2)
SSS: SSUSC84_0940(lacD) SSUSC84_1128(lacD2)
SGO: SGO_1516(lacD-2) SGO_1523(lacD-1)
SEQ: SZO_12150 SZO_15260(lacD)
SEZ: Sez_0456(lacD) Sez_0739
SEU: SEQ_0864
SUB: SUB0796(lacD2) SUB1454(lacD1)
SDS: SDEG_1758(lacD.1)
LJO: LJ0142
LJF: FI9785_209(lacD)
LCA: LSEI_0678 LSEI_2597
LCB: LCABL_07440(lacD2) LCABL_27630(lacD2)
LGA: LGAS_0145
LRH: LGG_00665(lacD) LGG_02575(lacD)
LRL: LC705_00639(lacD) LC705_02583(lacD)
PPE: PEPE_0143
EFA: EF0696(lacD-1) EF1807(lacD-2)
CAC: CAC2952(gatY)
CPE: CPE2626(gatY)
CPF: CPF_2962(gatY)
CPR: CPR_2645(gatY)
CNO: NT01CX_0290
CDF: CD3074(gatY) CD3448(gatY)
CDC: CD196_2866(agaY) CD196_3224(agaY)
CDL: CDR20291_2913(agaY) CDR20291_3270(agaY)
CBO: CBO1993(gatY)
CBA: CLB_1933(gatY)
CBH: CLC_1939(gatY)
CBY: CLM_2210
CBL: CLK_1446(gatY)
CBK: CLL_A3127(gatY)
CBB: CLD_2631(gatY)
CBI: CLJ_B2198
CBT: CLH_2877(gatY)
CBF: CLI_2060(gatY)
APR: Apre_0079
MTA: Moth_0609
HOR: Hore_22740
MMY: MSC_0644(fbaA1)
MCP: MCAP_0616
MSM: MSMEG_0898
ART: Arth_0275
AAU: AAur_0257
BCV: Bcav_3536
NML: Namu_3974
APV: Apar_1070
ABA: Acid345_1612
ACA: ACP_2824(lacD)
SUS: Acid_1436
SRU: SRU_2019(lacD)
DFE: Dfer_1705
LBA: Lebu_0587
STR: Sterm_3383 Sterm_3960
SMF: Smon_0139
CYN: Cyan7425_4035
GVI: glr2533
DET: DET1345
DEH: cbdb_A1295
DEB: DehaBAV1_1156
DEV: DhcVS_1127
RRS: RoseRS_1830
RCA: Rcas_2514
CAU: Caur_1070
CAG: Cagg_3347
CHL: Chy400_1171
KOL: Kole_0737
TTR: Tter_1238
 |
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| Structures |
PDB: 1GVF 3IV3 3JRK 3KAO |
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Reference
Authors
Title
Journal
|
1
Anderson, R.L., Markwell, J.P.
D-Tagatose-1,6-bisphosphate aldolase (Class II) from Klebsiella
pneumoniae.
Methods Enzymol. 90 (1982) 323-324. |
|---|
Reference
Authors
Title
Journal
Organism
Sequence
|
2 [PMID:1901863]
van Rooijen RJ, van Schalkwijk S, de Vos WM.
Molecular cloning, characterization, and nucleotide sequence of the
tagatose 6-phosphate pathway gene cluster of the lactose operon of
Lactococcus lactis.
J. Biol. Chem. 266 (1991) 7176-81.
Lactococcus lactis
NCBI-GI: 149396 |
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| Other DBs |
ExplorEnz - The Enzyme Database: 4.1.2.40
IUBMB Enzyme Nomenclature: 4.1.2.40
ExPASy - ENZYME nomenclature database: 4.1.2.40
BRENDA, the Enzyme Database: 4.1.2.40
CAS: 39433-95-9 |
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