| Entry |
|
|---|
| Name |
citramalate lyase;
citramalate pyruvate-lyase;
citramalate synthase;
citramalic-condensing enzyme;
citramalate synthetase;
citramalic synthase;
(S)-citramalate lyase;
(+)-citramalate pyruvate-lyase;
citramalate pyruvate lyase;
(3S)-citramalate pyruvate-lyase;
(2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase |
|---|
| Class |
Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
 |
|---|
| Sysname |
(2S)-2-hydroxy-2-methylbutanedioate pyruvate-lyase (acetate-forming) |
|---|
| Reaction(IUBMB) |
(2S)-2-hydroxy-2-methylbutanedioate = acetate + pyruvate [RN:R00325] |
|---|
| Reaction(KEGG) |
R00325
 |
|---|
| Substrate |
(2S)-2-hydroxy-2-methylbutanedioate [CPD:C02614] |
|---|
| Product |
acetate [CPD:C00033];
pyruvate [CPD:C00022] |
|---|
| Comment |
The enzyme can be dissociated into components, two of which are
identical with EC 2.8.3.11 (citramalate CoA-transferase) and EC
4.1.3.25 (citramalyl-CoA lyase). |
|---|
| Pathway |
PATH: ec00660 C5-Branched dibasic acid metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4301387]
Barker HA.
Citramalate lyase of Clostridium tetanomorphum.
Arch. Mikrobiol. 59 (1967) 4-12.
Clostridium tetanomorphum |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:923590]
Dimroth P, Buckel W, Loyal R, Eggerer H.
Isolation and function of the subunits of citramalate lyase and
formation of hybrids with the subunits of citrate lyase.
Eur. J. Biochem. 80 (1977) 469-77.
Clostridium tetanomorphum |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.1.3.22
IUBMB Enzyme Nomenclature: 4.1.3.22
ExPASy - ENZYME nomenclature database: 4.1.3.22
BRENDA, the Enzyme Database: 4.1.3.22
CAS: 9027-93-4 |
|---|
