KEGG   ENZYME: 4.2.1.12Help
Entry
EC 4.2.1.12                 Enzyme                                 
Name phosphogluconate dehydratase;
6-phosphogluconate dehydratase;
6-phosphogluconic dehydrase;
gluconate-6-phosphate dehydratase;
gluconate 6-phosphate dehydratase;
6-phosphogluconate dehydrase;
6-phospho-D-gluconate hydro-lyase
Class Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname 6-phospho-D-gluconate hydro-lyase
(2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)
Reaction(IUBMB) 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate +
H2O [RN:R02036]
Reaction(KEGG) R02036
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Substrate 6-phospho-D-gluconate [CPD:C00345]
Product 2-dehydro-3-deoxy-6-phospho-D-gluconate [CPD:C04442];
H2O [CPD:C00001]
Pathway PATH: ec00030  Pentose phosphate pathway
PATH: ec01100  Metabolic pathways
Orthology KO: K01690  phosphogluconate dehydratase
Genes ECO: b1851(edd)
ECJ: JW1840(edd)
ECD: ECDH10B_1992(edd)
EBW: BWG_1665(edd)
ECE: Z2903(edd)
ECS: ECs2561
ECF: ECH74115_2586(edd)
ETW: ECSP_2425(edd)
ECG: E2348C_1976(edd)
ECC: c2264(edd)
ECI: UTI89_C2054(edd)
ECP: ECP_1795
ECV: APECO1_901(edd)
ECW: EcE24377A_2081(edd)
ECX: EcHS_A1943(edd)
ECM: EcSMS35_1336(edd)
ECY: ECSE_2026
ECL: EcolC_1781
ECK: EC55989_2029(edd)
ECQ: ECED1_2056(edd)
ECR: ECIAI1_1924(edd)
ECT: ECIAI39_1199(edd)
ECZ: ECS88_1907(edd)
EUM: ECUMN_2148(edd)
ELF: LF82_0547(edd)
EBL: B21_01810(edd)
EBD: ECBD_1788
EBR: ECB_01822(edd)
EOH: ECO103_2041(edd)
EOI: ECO111_2359(edd)
EOJ: ECO26_2689(edd)
EFE: EFER_1222(edd)
STY: STY2093(edd)
STT: t0992(edd)
SPT: SPA0984(edd)
SEK: SSPA0918
SPQ: SPAB_01284
SEI: SPC_1831(edd)
SEC: SC1890(edd)
SEH: SeHA_C2099(edd)
SEE: SNSL254_A2044(edd)
SEW: SeSA_A2039(edd)
SEA: SeAg_B1239(edd)
SED: SeD_A1363(edd)
SEG: SG1167(edd)
SET: SEN1118(edd)
SES: SARI_01061
STM: STM1885(edd)
YPE: YPO2533(edd)
YPK: y1654(edd)
YPM: YP_2344(edd)
YPA: YPA_2025
YPN: YPN_2128
YPG: YpAngola_A1791(edd)
YPP: YPDSF_1943
YPS: YPTB2565(edd)
YPI: YpsIP31758_1476(edd)
YPY: YPK_1582
YPB: YPTS_2660
YEN: YE1368(edd)
SFL: SF1861(edd)
SFX: S1927(edd)
SFV: SFV_1853(edd)
SSN: SSON_1297(edd)
SBO: SBO_1159(edd)
SBC: SbBS512_E2126(edd)
SDY: SDY_1137(edd)
ECA: ECA1836(edd)
PWA: Pecwa_2771
ENT: Ent638_2420
ESA: ESA_01390
CTU: Ctu_25330(edd)
KPN: KPN_02366(edd)
KPE: KPK_1923(edd)
KPU: KP1_3495(edd)
CKO: CKO_01115
SPE: Spro_4499
PMR: PMI2760(edd)
EIC: NT01EI_1609
ETR: ETAE_1451
DDA: Dd703_1227
XFA: XF1062
XFT: PD0343(edd)
XFM: Xfasm12_0371
XFN: XfasM23_0335
XCC: XCC2139(edd)
XCB: XC_1974
XCA: xccb100_2039(edd)
XCV: XCV2234(edd)
XAC: XAC2068(edd)
XOO: XOO2317(edd)
XOM: XOO_2194
XOP: PXO_00611(edd)
SML: Smlt1790(edd)
SMT: Smal_1528
VCH: VC0288
VCO: VC0395_A2666(edd)
VCM: VCM66_0273(edd)
VCJ: VCD_001332
VVU: VV1_1099
VVY: VV0059
VPA: VP0062
VHA: VIBHAR_00512
VEX: VEA_001960
VFM: VFMJ11_A1080(edd)
VSA: VSAL_II0667(edd)
PAE: PA3194(edd)
PAU: PA14_22910(edd)
PAP: PSPA7_1934(edd)
PAG: PLES_18741(edd)
PPU: PP_1010(edd)
PPF: Pput_1048
PPG: PputGB1_1009
PPW: PputW619_4214
PST: PSPTO_1288(edd)
PSB: Psyr_1109
PSP: PSPPH_1177(edd)
PFL: PFL_4622(edd)
PFO: Pfl01_4375
PFS: PFLU4964
PEN: PSEEN4417(edd)
PMY: Pmen_1312
PSA: PST_2444 PST_3500
CJA: CJA_1349(edd)
AVN: Avin_15680(edd-1) Avin_27280(edd-2)
ACI: ACIAD0542(edd)
ACB: A1S_0483
ABM: ABSDF3021(edd)
ABY: ABAYE3281(edd)
ABC: ACICU_00494
ABN: AB57_0587(edd)
ABB: ABBFA_003050(edd)
SON: SO_2487(edd)
SDN: Sden_2077
SFR: Sfri_1894
SAZ: Sama_1810
SBL: Sbal_2239 Sbal_4525
SBM: Shew185_2132
SBN: Sbal195_2177
SBP: Sbal223_2252
SLO: Shew_2046
SPC: Sputcn32_1868
SSE: Ssed_2072
SPL: Spea_2333
SHE: Shewmr4_2044
SHM: Shewmr7_1931
SHN: Shewana3_2149
SHW: Sputw3181_2140
SHL: Shal_1951
SWD: Swoo_2537
SWP: swp_2392
CPS: CPS_2283(edd)
PHA: PSHAa1366(edd)
PAT: Patl_0972
SDE: Sde_1381
MAQ: Maqu_1830
AMC: MADE_01246
LPN: lpg0418(edd)
LPF: lpl0461(edd)
LPP: lpp0485(edd)
LPC: LPC_2925(edd)
MCA: MCA0037(edd)
HCH: HCH_00433(edd)
CSA: Csal_0936
MMW: Mmwyl1_1080
AHA: AHA_0288(edd)
ASA: ASA_4109(edd)
TAU: Tola_0777 Tola_1795
NMA: NMA1610(edd)
NME: NMB1393(edd)
NMC: NMC1332(edd)
NMN: NMCC_1308(edd)
NMI: NMO_1235(edd)
NGO: NGO0714
NGK: NGK_1176
CVI: CV_0144(edd)
RSO: RSp1560(edd)
RPI: Rpic_4868
RPF: Rpic12D_3791
REU: Reut_A1081 Reut_B5330
REH: H16_A1178(edd1) H16_B2567(edd2)
RME: Rmet_1045 Rmet_5802
CTI: RALTA_A1158(edd) RALTA_B2297(edd)
BMA: BMA2446(edd)
BMV: BMASAVP1_A0363(edd)
BML: BMA10229_A1221(edd)
BMN: BMA10247_2632(edd)
BPS: BPSL2932(edd)
BPM: BURPS1710b_3442(edd)
BPL: BURPS1106A_3442(edd)
BPD: BURPS668_3407(edd)
BPR: GBP346_A3587(edd)
BTE: BTH_I1217(edd)
BVI: Bcep1808_0628
BUR: Bcep18194_A3746
BCN: Bcen_0177
BCH: Bcen2424_0660
BCM: Bcenmc03_0627
BCJ: BCAL3367(edd)
BAM: Bamb_0555
BAC: BamMC406_0581
BMU: Bmul_2723
BMJ: BMULJ_00514(edd)
BXE: Bxe_A0589
BPH: Bphy_2580
BPY: Bphyt_3370
BGL: bglu_1g05520
RFR: Rfer_2060
POL: Bpro_3551
PNA: Pnap_2986
AAV: Aave_2793
AJS: Ajs_2049
VEI: Veis_2570
DAC: Daci_3765
DIA: Dtpsy_1872
VAP: Vapar_3708
CTT: CtCNB1_3428
HAR: HEAR1086(edd)
MMS: mma_2311(edd)
LCH: Lcho_2919
MFA: Mfla_0759
MMB: Mmol_1727
MEI: Msip34_1897
HPY: HP1100
HPJ: jhp1026(edd)
HPA: HPAG1_1038
HPS: HPSH_05650
HPG: HPG27_1041
HPP: HPP12_1065(edd)
HPB: HELPY_1069(edd)
HAC: Hac_0442(edd)
CJD: JJD26997_1271(edd)
HOH: Hoch_4430
MLO: mll6512
MES: Meso_0157
SME: SMc03068(edd)
SMD: Smed_0298
ATU: Atu0598(edd)
ATC: AGR_C_1060
ARA: Arad_0942(edd)
AVI: Avi_0796(edd)
RET: RHE_CH00702(edd)
REC: RHECIAT_CH0000783(edd)
RLE: RL0751(edd)
RLT: Rleg2_0361
RLG: Rleg_0393
RHI: NGR_c03170
BME: BMEII0511
BMI: BMEA_B0758(edd)
BMF: BAB2_0458
BMB: BruAb2_0452
BMC: BAbS19_II04330
BOV: BOV_A0730(edd)
BCS: BCAN_B0792(edd)
BMR: BMI_II773
OAN: Oant_3958
BHE: BH03930(edd)
BTR: Btr_0601(edd)
BGR: Bgr_04230(edd)
XAU: Xaut_1018 Xaut_1698
AZC: AZC_2424
MEX: Mext_2007
MEA: Mex_1p1986(edd)
MDI: METDI2774(edd)
MRD: Mrad2831_3428
MET: M446_3524
MPO: Mpop_1963
MCH: Mchl_2284
BID: Bind_2868
MSL: Msil_1124
CCR: CC_2055
CCS: CCNA_02134(edd)
CAK: Caul_1440
PZU: PHZ_c3252(edd)
SIL: SPO3032(edd)
SIT: TM1040_0376
RSH: Rsph17029_1303
RSQ: Rsph17025_1181
RSK: RSKD131_0957
JAN: Jann_1953
RDE: RD1_2879(edd)
PDE: Pden_1955
DSH: Dshi_1769(edd)
MMR: Mmar10_2640
HNE: HNE_1740(edd)
HBA: Hbal_1546
ZMO: ZMO0368
ZMN: Za10_0872
NAR: Saro_1895
SAL: Sala_0191
SWI: Swit_1624 Swit_1727
ELI: ELI_00540
GOX: GOX0431
GBE: GbCGDNIH1_2043
ACR: Acry_0466
MSM: MSMEG_0313(edd)
RHA: RHA1_ro02368(edd)
ROP: ROP_20820(edd)
TCU: Tcur_1742
SRO: Sros_3373
FRE: Franean1_7021 Franean1_7067
SEN: SACE_1740(edd)
SVI: Svir_27780
AMI: Amir_1423
Taxonomy
Structures PDB: 2GP4  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:14245409]
MELOCHE HP, WOOD WA.
THE MECHANISM OF 6-PHOSPHOGLUCONIC DEHYDRASE.
J. Biol. Chem. 239 (1964) 3505-10.
Pseudomonas fluorescens
Other DBs ExplorEnz - The Enzyme Database: 4.2.1.12
IUBMB Enzyme Nomenclature: 4.2.1.12
ExPASy - ENZYME nomenclature database: 4.2.1.12
BRENDA, the Enzyme Database: 4.2.1.12
CAS: 9024-33-3
DBGET integrated database retrieval system