| Entry |
|
|---|
| Name |
propanediol dehydratase;
meso-2,3-butanediol dehydrase;
diol dehydratase;
DL-1,2-propanediol hydro-lyase;
diol dehydrase;
adenosylcobalamin-dependent diol dehydratase;
propanediol dehydrase;
coenzyme B12-dependent diol dehydrase;
1,2-propanediol dehydratase;
dioldehydratase;
propane-1,2-diol hydro-lyase |
|---|
| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
 |
|---|
| Sysname |
propane-1,2-diol hydro-lyase (propanal-forming) |
|---|
| Reaction(IUBMB) |
propane-1,2-diol = propanal + H2O [RN:R02376] |
|---|
| Reaction(KEGG) |
R02376
 |
|---|
| Substrate |
propane-1,2-diol [CPD:C00583] |
|---|
| Product |
propanal [CPD:C00479];
H2O [CPD:C00001] |
|---|
| Cofactor |
Cobamide [CPD:C00210] |
|---|
| Comment |
Requires a cobamide coenzyme. Also dehydrates ethylene glycol to
acetaldehyde. |
|---|
| Pathway |
PATH: ec00561 Glycerolipid metabolism |
|---|
| Orthology |
KO: K01699 diol dehydratase |
|---|
| Genes |
RET: RHE_CH03790(yhch01100)
BME: BMEI0092
GOX: GOX0183
CGB: cg2830(pduO)
FAL: FRAAL5927
SEN: SACE_6271
FNU: FN1303
 |
|---|
| Structures |
PDB: 1DIO 1EEX 1EGM 1EGV 1IWB 1UC4 1UC5 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13680987]
ABELES RH, LEE HA Jr.
An intramolecular oxidation-reduction requiring a cobamide coenzyme.
J. Biol. Chem. 236 (1961) 2347-50.
Aerobacter aerogenes |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:7035429]
Forage RG, Foster MA.
Glycerol fermentation in Klebsiella pneumoniae: functions of the
coenzyme B12-dependent glycerol and diol dehydratases.
J. Bacteriol. 149 (1982) 413-9.
Klebsiella pneumoniae |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13929077]
LEE HA Jr, ABELES RH.
Purification and properties of dioldehydrase, and enzyme requiring a
cobamide coenzyme.
J. Biol. Chem. 238 (1963) 2367-73.
Aerobacter aerogenes |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.2.1.28
IUBMB Enzyme Nomenclature: 4.2.1.28
ExPASy - ENZYME nomenclature database: 4.2.1.28
BRENDA, the Enzyme Database: 4.2.1.28
CAS: 9026-90-8 |
|---|
