KEGG   ENZYME: 4.2.1.30Help
Entry
EC 4.2.1.30                 Enzyme                                 
Name glycerol dehydratase;
glycerol dehydrase;
glycerol hydro-lyase
Class Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname glycerol hydro-lyase (3-hydroxypropanal-forming)
Reaction(IUBMB) glycerol = 3-hydroxypropanal + H2O [RN:R01047]
Reaction(KEGG) R01047;
(other) R01048
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Substrate glycerol [CPD:C00116]
Product 3-hydroxypropanal [CPD:C00969];
H2O [CPD:C00001]
Cofactor Cobamide [CPD:C00210]
Comment Requires a cobamide coenzyme.
Pathway PATH: ec00561  Glycerolipid metabolism
Orthology KO: K06120  glycerol dehydratase large subunit
KO: K06121  glycerol dehydratase medium subunit
KO: K06122  glycerol dehydratase small subunit
Genes ECG: E2348C_2132(pduC) E2348C_2133(pduD) E2348C_2134(pduE)
ECW: EcE24377A_2281(pduC) EcE24377A_2282(pduD) EcE24377A_2283(pduE)
EUM: ECUMN_2336(pduC) ECUMN_2337(pduD) ECUMN_2338(pduE)
ELF: LF82_p332 LF82_p333 LF82_p334
EFE: EFER_2010(pduC) EFER_2011(pduD) EFER_2012(pduE)
STY: STY2245(pduC) STY2246(pduD) STY2247(pduE)
STT: t0832(pduE) t0833(pduD) t0834(pduC)
SPT: SPA0829(pduE) SPA0830(pduD) SPA0831(pduC)
SEK: SSPA0776 SSPA0777 SSPA0778
SPQ: SPAB_01062 SPAB_01063 SPAB_01064
SEI: SPC_1672(pduE) SPC_1673(pduD) SPC_1674(pduC)
SEC: SC2048(pduC) SC2049(pduD) SC2050(pduE)
SEH: SeHA_C2263(pduC) SeHA_C2264 SeHA_C2265
SEE: SNSL254_A2217(pduC) SNSL254_A2218 SNSL254_A2219
SEW: SeSA_A2210(pduC) SeSA_A2211 SeSA_A2212
SEA: SeAg_B2163(pduC) SeAg_B2164 SeAg_B2165
SED: SeD_A2376(pduC) SeD_A2377 SeD_A2378
SEG: SG2067(pduC) SG2068(pduD) SG2069(pduE)
SET: SEN2038(pduC) SEN2039(pduD) SEN2040(pduE)
SES: SARI_00845 SARI_00846 SARI_00847
STM: STM2040(pduC) STM2041(pduD) STM2042(pduE)
YEN: YE2730(pddA) YE2731(pddB) YE2732(pddC)
SSN: SSON_2060(pduC) SSON_2061(pduD) SSON_2062(pduE)
KPN: KPN_03205(pduC) KPN_03206(pduD) KPN_03207(pduE)
     KPN_03487(dhaB3) KPN_03488(dhaB2) KPN_03489(dhaB1)
KPE: KPK_0626(dhaB) KPK_0627(dhaC) KPK_0628(dhaE) KPK_0908(pduE)
     KPK_0909(pduD) KPK_0910(pduC)
KPU: KP1_4473(pduC) KP1_4474(pduD) KP1_4475(pduE) KP1_4780(dhaB3)
     KP1_4781(dhaB2) KP1_4782(dhaB1)
CKO: CKO_00794 CKO_00795 CKO_00796
TAU: Tola_1686 Tola_1687 Tola_1688
DAL: Dalk_4997 Dalk_4998 Dalk_4999
MLO: mll6721 mll6722
LMO: lmo1153 lmo1154 lmo1155
LMF: LMOf2365_1161(pduC) LMOf2365_1162(pduD) LMOf2365_1163(pduE)
LMH: LMHCC_1496 LMHCC_1497 LMHCC_1498
LMC: Lm4b_01158 Lm4b_01159 Lm4b_01160
LIN: lin1117 lin1118 lin1119
LWE: lwe1111(pduC) lwe1112(pduD) lwe1113(pduE)
SSA: SSA_0533(pduC) SSA_0535 SSA_0536
LBR: LVIS_1613 LVIS_1614 LVIS_1615
LRE: Lreu_1745 Lreu_1746 Lreu_1747
LRF: LAR_1633 LAR_1634 LAR_1635
CPE: CPE0929 CPE0930 CPE0931
CPF: CPF_1173 CPF_1174 CPF_1175
CPR: CPR_1004(dhaB) CPR_1005(dhaC) CPR_1006(dhaE)
CBK: CLL_A2103 CLL_A2104 CLL_A2105
CBT: CLH_1940 CLH_1941 CLH_1942
CKL: CKL_0843(dhaA) CKL_0844(dhaC)
CKR: CKR_0756 CKR_0757
TEX: Teth514_1951 Teth514_1952 Teth514_1953
MSM: MSMEG_0496 MSMEG_0497 MSMEG_1546 MSMEG_1547 MSMEG_1548
     MSMEG_6320 MSMEG_6321
MVA: Mvan_5562 Mvan_5563
MGI: Mflv_1245 Mflv_1246
MMC: Mmcs_4953 Mmcs_4954
MKM: Mkms_5041 Mkms_5042
MJL: Mjls_5334 Mjls_5335
STR: Sterm_1031 Sterm_1032 Sterm_1033
Taxonomy
Structures PDB: 1IWP  1MMF  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:7035429]
Forage RG, Foster MA.
Glycerol fermentation in Klebsiella pneumoniae: functions of the
coenzyme B12-dependent glycerol and diol dehydratases.
J. Bacteriol. 149 (1982) 413-9.
Klebsiella pneumoniae [GN:kpn]
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:4989992]
Schneider Z, Larsen EG, Jacobson G, Johnson BC, Pawelkiewicz J.
Purification and properties of glycerol dehydrase.
J. Biol. Chem. 245 (1970) 3388-96.
Aerobacter aerogenes
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:5962440]
Schneider Z, Pawelkiewicz J.
The properties of glycerol dehydratase isolated from Aerobacter
aerogenes, and the properties of the apoenzyme subunits.
Acta. Biochim. Pol. 13 (1966) 311-28.
Aerobacter aerogenes
Reference
  Authors
  Title

  Journal
  Organism
 4  [PMID:14039344]
SMILEY KL, SOBOLOV M.
A cobamide-requiring glycerol dehydrase from an acrolein-forming
Lactobacillus.
Arch. Biochem. Biophys. 97 (1962) 538-43.
Lactobacillus sp.
Other DBs ExplorEnz - The Enzyme Database: 4.2.1.30
IUBMB Enzyme Nomenclature: 4.2.1.30
ExPASy - ENZYME nomenclature database: 4.2.1.30
BRENDA, the Enzyme Database: 4.2.1.30
CAS: 9077-68-3
DBGET integrated database retrieval system