KEGG   ENZYME: 4.2.1.34Help
Entry
EC 4.2.1.34                 Enzyme                                 

Name (S)-2-methylmalate dehydratase;
mesaconate hydratase;
(+)-citramalate hydro-lyase;
L-citramalate hydrolase;
citramalate dehydratase;
(+)-citramalic hydro-lyase;
mesaconate mesaconase;
mesaconase;
(S)-2-methylmalate hydro-lyase
Class Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname (S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)
Reaction(IUBMB) (S)-2-methylmalate = 2-methylfumarate + H2O [RN:R03693]
Reaction(KEGG) R03693
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Substrate (S)-2-methylmalate [CPD:C02614]
Product 2-methylfumarate [CPD:C01732];
H2O [CPD:C00001]
Comment Also hydrates fumarate to (S)-malate.
Pathway PATH: ec00660  C5-Branched dibasic acid metabolism
PATH: ec01100  Metabolic pathways
Reference
  Authors
  Title

  Journal
  Organism
1  [PMID:5903732]
Blair AH, Barker HA.
Assay and purification of (+)-citramalate hydro-lyase components
from Clostridium tetanomorphum.
J. Biol. Chem. 241 (1966) 400-8.
Clostridium tetanomorphum
Reference
  Authors
  Title
  Journal
  Organism
2  [PMID:5769987]
Wang CC, Barker HA.
Purification and properties of L-citramalate hydrolyase.
J. Biol. Chem. 244 (1969) 2516-26.
Clostridium tetanomorphum
Other DBs ExplorEnz - The Enzyme Database: 4.2.1.34
IUBMB Enzyme Nomenclature: 4.2.1.34
ExPASy - ENZYME nomenclature database: 4.2.1.34
BRENDA, the Enzyme Database: 4.2.1.34
CAS: 9027-94-5

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