| Entry |
|
|---|
| Name |
dimethylmaleate hydratase;
(2R,3S)-2,3-dimethylmalate hydro-lyase |
|---|
| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
 |
|---|
| Sysname |
(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming) |
|---|
| Reaction(IUBMB) |
(2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O [RN:R03069] |
|---|
| Reaction(KEGG) |
R03069
 |
|---|
| Substrate |
(2R,3S)-2,3-dimethylmalate [CPD:C03652] |
|---|
| Product |
dimethylmaleate;
H2O [CPD:C00001] |
|---|
| Cofactor |
Iron [CPD:C00023] |
|---|
| Comment |
Requires Fe2+. Inhibited by oxygen. |
|---|
| Pathway |
PATH: ec00760 Nicotinate and nicotinamide metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6489933]
Kollmann-Koch A, Eggerer H.
Nicotinic acid metabolism. Dimethylmaleate hydratase.
Hoppe. Seylers. Z. Physiol. Chem. 365 (1984) 847-57.
Clostridium barkeri |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.2.1.85
IUBMB Enzyme Nomenclature: 4.2.1.85
ExPASy - ENZYME nomenclature database: 4.2.1.85
BRENDA, the Enzyme Database: 4.2.1.85
CAS: 93229-56-2 |
|---|
