| Entry |
|
|---|
| Name |
2-methylisocitrate dehydratase;
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase |
|---|
| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
 |
|---|
| Sysname |
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase
[(Z)-but-2-ene-1,2,3-tricarboxylate-forming] |
|---|
| Reaction(IUBMB) |
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate =
(Z)-but-2-ene-1,2,3-tricarboxylate + H2O [RN:R04425] |
|---|
| Reaction(KEGG) |
R04425
 |
|---|
| Substrate |
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate [CPD:C04593] |
|---|
| Product |
(Z)-but-2-ene-1,2,3-tricarboxylate [CPD:C04225];
H2O [CPD:C00001] |
|---|
| Comment |
The enzyme from the fungus Yarrowia lipolytica (Saccharomycopsis)
does not act on isocitrate. |
|---|
| Pathway |
PATH: ec00640 Propanoate metabolism |
|---|
| Orthology |
KO: K05608 2-methylisocitrate dehydratase |
|---|
| Genes |
BTE: BTH_II2187(acnD)
 |
|---|
Reference
Authors
Title
Journal
|
1
Aoki, H., Uchiyama, H., Umetsu, H., Tabuchi, T.
Isolation of 2-methylisocitrate dehydratase, a new enzyme serving in
the methylcitric acid cycle for propionate metabolism, from Yarrowia
lipolytica.
Biosci. Biotechnol. Biochem. 59 (1995) 1825-1828. |
|---|
Reference
Authors
Title
Journal
|
2
Tabuchi, T., Umetsu, H., Aoki, H., Uchiyama, H.
Characteristics of 2-methylisocitrate dehydratase, isolated from
Yarrowia lipolytica, in comparison to aconitase.
Biosci. Biotechnol. Biochem. 59 (1995) 2013-2017. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.2.1.99
IUBMB Enzyme Nomenclature: 4.2.1.99
ExPASy - ENZYME nomenclature database: 4.2.1.99
BRENDA, the Enzyme Database: 4.2.1.99
CAS: 170780-51-5 |
|---|
|
