KEGG   ENZYME: 4.2.2.2Help
Entry
EC 4.2.2.2                  Enzyme                                 

Name
pectate lyase;
polygalacturonic transeliminase;
pectic acid transeliminase;
polygalacturonate lyase;
endopectin methyltranseliminase;
pectate transeliminase;
endogalacturonate transeliminase;
pectic acid lyase;
pectic lyase;
alpha-1,4-D-endopolygalacturonic acid lyase;
PGA lyase;
PPase-N;
endo-alpha-1,4-polygalacturonic acid lyase;
polygalacturonic acid lyase;
pectin trans-eliminase;
Polygalacturonic acid trans-eliminase
Class
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
BRITE hierarchy
Sysname
(1->4)-alpha-D-galacturonan lyase
Reaction(IUBMB)
Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends [RN:R08694]
Reaction(KEGG)
Comment
Favours pectate, the anion, over pectin, the methyl ester (which is the preferred substrate of EC 4.2.2.10, pectin lyase).
History
EC 4.2.2.2 created 1965 as EC 4.2.99.3, transferred 1972 to EC 4.2.2.2, modified 2002
Pathway
Pentose and glucuronate interconversions
Orthology
K01728  
pectate lyase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
POPTR_0001s04460g(POPTRDRAFT_750465) POPTR_0001s14240g(POPTRDRAFT_547984) POPTR_0001s35960g(POPTRDRAFT_815540) POPTR_0002s23990g(POPTRDRAFT_409041) POPTR_0003s17450g(POPTRDRAFT_712008) POPTR_0006s12390g POPTR_0006s23090g(POPTRDRAFT_832050) POPTR_0008s04850g(POPTRDRAFT_720641) POPTR_0008s14810g(POPTRDRAFT_421334) POPTR_0008s18250g(POPTRDRAFT_565107) POPTR_0010s23570g(POPTRDRAFT_883326) POPTR_0011s00240g(POPTRDRAFT_1093113) POPTR_0011s09580g(POPTRDRAFT_234938) POPTR_0012s09310g(POPTRDRAFT_570188) POPTR_0015s07590g POPTR_0015s09930g(POPTRDRAFT_575272) POPTR_0016s08140g(POPTRDRAFT_777442) POPTR_0017s11450g(POPTRDRAFT_908365) POPTR_0021s00250g POPTR_282224 POPTR_581348
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0546800-01(Os01g0546800) Os02t0214400-01(Os02g0214400) Os06t0144200-01(Os06g0144200) Os06t0144900-01(Os06g0144900) Os06t0583900-01(Os06g0583900) Os08t0286100-00(Os08g0286100) Os10t0457200-00(Os10g0457200)
BDI: 
SBI: 
SORBI_01g020180(SORBIDRAFT_01g020180) SORBI_03g036930(SORBIDRAFT_03g036930) SORBI_03g039150(SORBIDRAFT_03g039150) SORBI_04g007450(SORBIDRAFT_04g007450) SORBI_06g001410(SORBIDRAFT_06g001410) SORBI_08g004905(SORBIDRAFT_08g004905) SORBI_10g003080(SORBIDRAFT_10g003080) SORBI_10g003090(SORBIDRAFT_10g003090) SORBI_10g022830(SORBIDRAFT_10g022830)
ZMA: 
SITA: 
SMO: 
PPP: 
PAN: 
MTM: 
MGR: 
FGR: 
NHE: 
VAL: 
SSL: 
BFU: 
ANI: 
NFI: 
AFM: 
AOR: 
AOR_1_1156054(AO090011000673) AOR_1_590114(AO090701000321)
ANG: 
ANI_1_102174(An10g00870)
AFV: 
PCS: 
PNO: 
ZTR: 
TML: 
MPR: 
CCI: 
SCM: 
YPE: 
YPO3994(pelY)
YPK: 
YPA: 
YPN: 
YPM: 
YP_3357(pelY)
YPG: 
YPZ: 
YPZ3_2172(pelY)
YPT: 
YPD: 
YPD4_3514(pelY)
YPX: 
YPD8_3520(pelY)
YPH: 
YPC_4503(pelY)
YPS: 
YPTB3834(pelY)
YPI: 
YPY: 
YPB: 
YEN: 
YE4069(pelY)
YEP: 
YEY: 
ECA: 
PCT: 
PCC: 
PWA: 
PEC: 
ENT: 
ENR: 
KOX: 
KOE: 
SERR: 
SFO: 
DDA: 
DDC: 
DDD: 
DZE: 
XCC: 
XCC0644(pel) XCC0645(pel) XCC2815(pelB)
XCB: 
XCA: 
XCV: 
XCP: 
XAC: 
XAC2373(pel) XAC2986(pelB) XAC3562(pel)
XAO: 
XOO: 
XOM: 
XOP: 
XOR: 
XCI: 
PFS: 
CJA: 
CJA_0533(pel1B) CJA_1277(pelC)
SDE: 
Sde_3448(pel1D)
HCH: 
MMW: 
MPC: 
SAGA: 
BPH: 
BGE: 
BPX: 
BUO: 
BPT: 
AXY: 
AXO: 
AXN: 
AAV: 
AAA: 
CCO: 
SCU: 
SME: 
SMD: 
BSU: 
BSR: 
BSL: 
BSH: 
BSY: 
BSS: 
BST: 
BSO: 
BSN: 
BSQ: 
BSUB: 
BSX: 
BSP: 
BLI: 
BL03760(pel)
BLD: 
BLH: 
BAO: 
BAY: 
BAQ: 
BYA: 
BAMP: 
BAML: 
BAMA: 
BAMN: 
BAMB: 
BAZ: 
BQL: 
BXH: 
BQY: 
BAMI: 
BAMC: 
BAMF: 
BAE: 
BHA: 
BCL: 
BPU: 
BPUM_3515(pelB)
BJS: 
GYM: 
PPY: 
PPM: 
PPO: 
PPM_3731(pel1)
PPOL: 
PMS: 
PMQ: 
PMW: 
PTA: 
MPS: 
LCI: 
LKI: 
LEC: 
CCE: 
CCB: 
CSB: 
BPB: 
bpr_I2372(pel1A)
SCO: 
SCO1880(SCI39.27c)
SMA: 
SGR: 
SCB: 
SSX: 
SVL: 
SFA: 
SBH: 
SVE: 
SDV: 
STRP: 
SFI: 
SRC: 
CMC: 
AAU: 
ACH: 
APN: 
ARR: 
IVA: 
TFU: 
NDA: 
TCU: 
SRO: 
TBI: 
AMD: 
AMN: 
AMM: 
AMZ: 
AMI: 
MAU: 
MIL: 
VMA: 
AMS: 
ASE: 
ACTN: 
AFS: 
TBE: 
SCD: 
FSU: 
FSC: 
RBA: 
NKO: 
FJO: 
FBA: 
TMA: 
TMM: 
TMI: 
TLE: 
TRQ: 
DTH: 
DTU: 
 » show all
Taxonomy
Reference
1  [PMID:13860094]
  Authors
ALBERSHEIM P, KILLIAS U.
  Title
Studies relating to the purification and properties of pectin transeliminase.
  Journal
Arch. Biochem. Biophys. 97 (1962) 107-15.
  Organism
Pisum sativum
Reference
2  [PMID:14235514]
  Authors
EDSTROM RD, PHAFF HJ.
  Title
PURIFICATION AND CERTAIN PROPERTIES OF PECTIN TRANS-ELIMINASE FROM ASPERGILLUS FONSECAEUS.
  Journal
J. Biol. Chem. 239 (1964) 2403-8.
  Organism
Aspergillus fonsecaeus
Reference
3  [PMID:14235515]
  Authors
EDSTROM RD, PHAFF HJ.
  Title
ELIMINATIVE CLEAVAGE OF PECTIN AND OF OLIGOGALACTURONIDE METHYL ESTERS BY PECTIN TRANS-ELIMINASE.
  Journal
J. Biol. Chem. 239 (1964) 2409-15.
  Organism
Aspergillus fonsecaeus
Reference
4  [PMID:13727438]
  Authors
NAGEL CW, VAUGHN RH.
  Title
The degradation of oligogalacturonides by the polygalacturonase of Bacillus polymyxa.
  Journal
Arch. Biochem. Biophys. 94 (1961) 328-32.
  Organism
Bacillus polymyxa
Reference
5  [PMID:6035509]
  Authors
Nasuno S, Starr MP.
  Title
Polygalacturonic acid trans-eliminase of Xanthomonas campestris.
  Journal
Biochem. J. 104 (1967) 178-85.
  Organism
Xanthomonas campestris
Reference
6  [PMID:9195887]
  Authors
Mayans O, Scott M, Connerton I, Gravesen T, Benen J, Visser J, Pickersgill R, Jenkins J.
  Title
Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases.
  Journal
Structure. 5 (1997) 677-89.
  Organism
Aspergillus niger [GN:ang]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9015-75-2

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