| Entry |
|
|---|
| Name |
(+)-delta-cadinene synthase |
|---|
| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
 |
|---|
| Sysname |
2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing,
(+)-delta-cadinene-forming) |
|---|
| Reaction(IUBMB) |
2-trans,6-trans-farnesyl diphosphate = (+)-delta-cadinene +
diphosphate [RN:R02311] |
|---|
| Reaction(KEGG) |
R02311
 |
|---|
| Substrate |
2-trans,6-trans-farnesyl diphosphate [CPD:C00448] |
|---|
| Product |
(+)-delta-cadinene [CPD:C06394];
diphosphate [CPD:C00013] |
|---|
| Cofactor |
Magnesium [CPD:C00305] |
|---|
| Comment |
The sesquiterpenoid (+)-delta-cadinene is an intermediate in
phytoalexin biosynthesis. Mg2+ is required for activity. |
|---|
| Pathway |
PATH: ec00909 Sesquiterpenoid biosynthesis
PATH: ec01062 Biosynthesis of terpenoids and steroids
PATH: ec01100 Metabolic pathways |
|---|
| Structures |
PDB: 3G4D 3G4F |
|---|
Reference
Authors
Title
Journal
Organism
Sequence
|
1 [PMID:8554317]
Chen XY, Chen Y, Heinstein P, Davisson VJ.
Cloning, expression, and characterization of (+)-delta-cadinene
synthase: a catalyst for cotton phytoalexin biosynthesis.
Arch. Biochem. Biophys. 324 (1995) 255-66.
Gossypium arboreum
NCBI-GI: 1045314 1045312 |
|---|
Reference
Authors
Title
Journal
Organism
Sequence
|
2 [PMID:8728715]
Davis EM, Tsuji J, Davis GD, Pierce ML, Essenberg M.
Purification of (+)-delta-cadinene synthase, a sesquiterpene cyclase
from bacteria-inoculated cotton foliar tissue.
Phytochemistry. 41 (1996) 1047-55.
Gossypium hirsutum
NCBI-GI: 3287832 |
|---|
Reference
Authors
Title
Journal
|
3
Davis, G.D., Essenberg, M.
(+)-delta-Cadinene is a product of sesquiterpene cyclase activity in
cotton.
Phytochemistry 39 (1995) 553-567. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.2.3.13
IUBMB Enzyme Nomenclature: 4.2.3.13
ExPASy - ENZYME nomenclature database: 4.2.3.13
BRENDA, the Enzyme Database: 4.2.3.13
CAS: 166800-09-5 |
|---|
