KEGG   ENZYME: 4.2.3.140Help
Entry
EC 4.2.3.140                Enzyme                                 

Name
cis-abienol synthase;
Z-abienol synthase;
CAS;
ABS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(13E)-8alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (cis-abienol forming)
Reaction(IUBMB)
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate = cis-abienol + diphosphate [RN:R10276]
Reaction(KEGG)
Substrate
(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate [CPD:C20270]
Product
cis-abienol [CPD:C20481];
diphosphate [CPD:C00013]
Comment
Isolated from the plants Abies balsamea (balsam fir) [1] and Nicotiana tabacum (tobacco) [2].
History
EC 4.2.3.140 created 2012
Reference
1  [PMID:22337889]
  Authors
Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R, Bohlmann J
  Title
Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production.
  Journal
J. Biol. Chem. 287 (2012) 12121-31.
  Organism
Abies balsamea
  Sequence
[up:H8ZM73]
Reference
2  [PMID:22672125]
  Authors
Sallaud C, Giacalone C, Topfer R, Goepfert S, Bakaher N, Rosti S, Tissier A
  Title
Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes.
  Journal
Plant. J. 72 (2012) 1-17.
  Organism
Nicotiana tabacum
  Sequence
[up:G3CCC1]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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