KEGG   ENZYME: 4.2.3.25Help
Entry
EC 4.2.3.25                 Enzyme                                 

Name
S-linalool synthase;
LIS;
Lis;
3S-linalool synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming]
Reaction(IUBMB)
geranyl diphosphate + H2O = (3S)-linalool + diphosphate [RN:R07631]
Reaction(KEGG)
Substrate
geranyl diphosphate [CPD:C00341];
H2O [CPD:C00001]
Product
(3S)-linalool [CPD:C11389];
diphosphate [CPD:C00013]
Comment
Requires Mn2+ or Mg2+ for activity. Neither (S)- nor (R)-linalyl diphosphate can act as substrate for the enzyme from the flower Clarkia breweri [1]. Unlike many other monoterpene synthases, only a single product, (3S)-linalool, is formed.
History
EC 4.2.3.25 created 2006
Pathway
Monoterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K15086  
(3S)-linalool synthase
Genes
ATH: 
AT1G61680(TPS14)
ALY: 
CRB: 
BRP: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0004s02970g(POPTRDRAFT_855580) POPTR_0004s02990g(POPTRDRAFT_856834) POPTR_0011s03490g
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os02t0121700-01(Os02g0121700) Os10t0489500-00(Os10g0489500)
OBR: 
BDI: 
SBI: 
SORBI_04g001760(SORBIDRAFT_04g001760) SORBI_04g001770(SORBIDRAFT_04g001770) SORBI_04g001780(SORBIDRAFT_04g001780) SORBI_04g001800(SORBIDRAFT_04g001800)
ZMA: 
SITA: 
MUS: 
ATR: 
s00003p00254990(AMTR_s00003p00254990) s00043p00175880(AMTR_s00043p00175880) s00043p00177130(AMTR_s00043p00177130) s00043p00183010(AMTR_s00043p00183010) s00043p00183580(AMTR_s00043p00183580) s00066p00144770(AMTR_s00066p00144770)
 » show all
Taxonomy
Reference
1  [PMID:7864636]
  Authors
Pichersky E, Lewinsohn E, Croteau R.
  Title
Purification and characterization of S-linalool synthase, an enzyme involved in the production of floral scent in Clarkia breweri.
  Journal
Arch. Biochem. Biophys. 316 (1995) 803-7.
Reference
2  [PMID:11532177]
  Authors
Lucker J, Bouwmeester HJ, Schwab W, Blaas J, van der Plas LH, Verhoeven HA.
  Title
Expression of Clarkia S-linalool synthase in transgenic petunia plants results in the accumulation of S-linalyl-beta-D-glucopyranoside.
  Journal
Plant. J. 27 (2001) 315-24.
Reference
3  [PMID:8768373]
  Authors
Dudareva N, Cseke L, Blanc VM, Pichersky E.
  Title
Evolution of floral scent in Clarkia: novel patterns of S-linalool synthase gene expression in the C. breweri flower.
  Journal
Plant. Cell. 8 (1996) 1137-48.
  Sequence
[up:Q96376]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
160477-81-6

DBGET integrated database retrieval system